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Adult type testicular granulosa cell tumor

MedGen UID:
272840
Concept ID:
C1515284
Neoplastic Process
Synonyms: Adult Testicular Granulosa Cell Tumor; adult testicular granulosa cell tumor; adult testicular granulosa cell tumour; Adult Type Testicular Granulosa Cell Tumor; adult type testicular granulosa cell tumor
 
Monarch Initiative: MONDO:0004548

Definition

A rare, low-grade malignant sex cord-stromal tumor that arises from the testis in adults. It is composed of granulosa cells in an often fibrothecomatous stroma. Several morphologic patterns have been identified and include insular, gyriform, trabecular, pseudosarcomatous, and solid. Gynecomastia is present in approximately a quarter of the patients. Metastases have been reported in a minority of patients. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult type testicular granulosa cell tumor

Professional guidelines

PubMed

Schultz KAP, Harris AK, Finch M, Dehner LP, Brown JB, Gershenson DM, Young RH, Field A, Yu W, Turner J, Cost NG, Schneider DT, Stewart DR, Frazier AL, Messinger Y, Hill DA
Gynecol Oncol 2017 Dec;147(3):521-527. Epub 2017 Oct 14 doi: 10.1016/j.ygyno.2017.09.034. PMID: 29037807Free PMC Article

Recent clinical studies

Diagnosis

Arzola J, Hutton RL, Baughman SM, Mora RV
Urology 2006 Nov;68(5):1121.e13-6. Epub 2006 Nov 7 doi: 10.1016/j.urology.2006.06.029. PMID: 17095056

Therapy

Harrison MR, Huang W, Liu G, Gee J
Oncology (Williston Park) 2009 Aug;23(9):792-5. PMID: 19777766Free PMC Article

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