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Childhood testicular choriocarcinoma

MedGen UID:
272469
•Concept ID:
C1333006
•
Neoplastic Process
Synonyms: Childhood Choriocarcinoma of Testis; childhood choriocarcinoma of testis; Childhood Choriocarcinoma of the Testis; childhood choriocarcinoma of the testis; Childhood Testicular Choriocarcinoma; childhood testicular choriocarcinoma; choriocarcinoma of testis of childhood; paediatric choriocarcinoma of testis; paediatric choriocarcinoma of the testis; paediatric testicular choriocarcinoma; Pediatric Choriocarcinoma of Testis; pediatric choriocarcinoma of testis; Pediatric Choriocarcinoma of the Testis; pediatric choriocarcinoma of the testis; Pediatric Testicular Choriocarcinoma; pediatric testicular choriocarcinoma
 
Monarch Initiative: MONDO:0003786

Definition

A choriocarcinoma that arises from the testis during childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood testicular choriocarcinoma

Professional guidelines

PubMed

Malignant germ cell tumors: clinical characteristics, treatment, and outcome. A report from the study group for Pediatric Solid Malignant Tumors in the Kyushu Area, Japan.
Suita S, Shono K, Tajiri T, Takamatsu T, Mizote H, Nagasaki A, Inomata Y, Hara T, Okamura J, Miyazaki S, Kawakami K, Eguchi H, Tsuneyoshi M; Committee for Pediatric Solid Malignant Tumors in the Kyushu Area
J Pediatr Surg 2002 Dec;37(12):1703-6. doi: 10.1053/jpsu.2002.36700. PMID: 12483635
Progress in the systemic treatment of cancer. Concepts, trials, drugs, and biologics.
Carbone PP
Cancer 1990 Feb 1;65(3 Suppl):625-33. doi: 10.1002/1097-0142(19900201)65:3+<625::aid-cncr2820651305>3.0.co;2-y. PMID: 2302652

Recent clinical studies

Etiology

Intratubular germ cell neoplasia of the testis: a brief review.
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Clinical observations on chemotherapy curable malignancies: unique genetic events, frozen development and enduring apoptotic potential.
Savage P
BMC Cancer 2015 Jan 21;15:11. doi: 10.1186/s12885-015-1006-6. PMID: 25605631Free PMC Article
Epidemiologic analysis of 1,442 children and adolescents registered in the German germ cell tumor protocols.
Schneider DT, Calaminus G, Koch S, Teske C, Schmidt P, Haas RJ, Harms D, Göbel U
Pediatr Blood Cancer 2004 Feb;42(2):169-75. doi: 10.1002/pbc.10321. PMID: 14752882
Malignant germ cell tumors: clinical characteristics, treatment, and outcome. A report from the study group for Pediatric Solid Malignant Tumors in the Kyushu Area, Japan.
Suita S, Shono K, Tajiri T, Takamatsu T, Mizote H, Nagasaki A, Inomata Y, Hara T, Okamura J, Miyazaki S, Kawakami K, Eguchi H, Tsuneyoshi M; Committee for Pediatric Solid Malignant Tumors in the Kyushu Area
J Pediatr Surg 2002 Dec;37(12):1703-6. doi: 10.1053/jpsu.2002.36700. PMID: 12483635

Diagnosis

Clinical observations on chemotherapy curable malignancies: unique genetic events, frozen development and enduring apoptotic potential.
Savage P
BMC Cancer 2015 Jan 21;15:11. doi: 10.1186/s12885-015-1006-6. PMID: 25605631Free PMC Article
Epidemiologic analysis of 1,442 children and adolescents registered in the German germ cell tumor protocols.
Schneider DT, Calaminus G, Koch S, Teske C, Schmidt P, Haas RJ, Harms D, Göbel U
Pediatr Blood Cancer 2004 Feb;42(2):169-75. doi: 10.1002/pbc.10321. PMID: 14752882
Germinal testicular tumors in childhood. Report of observations and literature review.
Weissbach L, Altwein JE, Stiens R
Eur Urol 1984;10(2):73-85. doi: 10.1159/000463762. PMID: 6368238
Gonadal and extragonadal germ cell neoplasia of childhood.
Dehner LP
Hum Pathol 1983 Jun;14(6):493-511. doi: 10.1016/s0046-8177(83)80004-5. PMID: 6343221
Ectopic hormone syndromes associated with tumors in childhood.
Omenn GS
Pediatrics 1971 Mar;47(3):613-22. PMID: 4323281

Therapy

Clinical observations on chemotherapy curable malignancies: unique genetic events, frozen development and enduring apoptotic potential.
Savage P
BMC Cancer 2015 Jan 21;15:11. doi: 10.1186/s12885-015-1006-6. PMID: 25605631Free PMC Article
Malignant germ cell tumors: clinical characteristics, treatment, and outcome. A report from the study group for Pediatric Solid Malignant Tumors in the Kyushu Area, Japan.
Suita S, Shono K, Tajiri T, Takamatsu T, Mizote H, Nagasaki A, Inomata Y, Hara T, Okamura J, Miyazaki S, Kawakami K, Eguchi H, Tsuneyoshi M; Committee for Pediatric Solid Malignant Tumors in the Kyushu Area
J Pediatr Surg 2002 Dec;37(12):1703-6. doi: 10.1053/jpsu.2002.36700. PMID: 12483635
Progress in the systemic treatment of cancer. Concepts, trials, drugs, and biologics.
Carbone PP
Cancer 1990 Feb 1;65(3 Suppl):625-33. doi: 10.1002/1097-0142(19900201)65:3+<625::aid-cncr2820651305>3.0.co;2-y. PMID: 2302652

Prognosis

Malignant germ cell tumors: clinical characteristics, treatment, and outcome. A report from the study group for Pediatric Solid Malignant Tumors in the Kyushu Area, Japan.
Suita S, Shono K, Tajiri T, Takamatsu T, Mizote H, Nagasaki A, Inomata Y, Hara T, Okamura J, Miyazaki S, Kawakami K, Eguchi H, Tsuneyoshi M; Committee for Pediatric Solid Malignant Tumors in the Kyushu Area
J Pediatr Surg 2002 Dec;37(12):1703-6. doi: 10.1053/jpsu.2002.36700. PMID: 12483635
Germinal testicular tumors in childhood. Report of observations and literature review.
Weissbach L, Altwein JE, Stiens R
Eur Urol 1984;10(2):73-85. doi: 10.1159/000463762. PMID: 6368238
Gonadal and extragonadal germ cell neoplasia of childhood.
Dehner LP
Hum Pathol 1983 Jun;14(6):493-511. doi: 10.1016/s0046-8177(83)80004-5. PMID: 6343221

Clinical prediction guides

Clinical observations on chemotherapy curable malignancies: unique genetic events, frozen development and enduring apoptotic potential.
Savage P
BMC Cancer 2015 Jan 21;15:11. doi: 10.1186/s12885-015-1006-6. PMID: 25605631Free PMC Article
Activation of Wnt/beta-catenin signaling in distinct histologic subtypes of human germ cell tumors.
Fritsch MK, Schneider DT, Schuster AE, Murdoch FE, Perlman EJ
Pediatr Dev Pathol 2006 Mar-Apr;9(2):115-31. Epub 2006 Jun 16 doi: 10.2350/08-05-0097.1. PMID: 16822086
Epidemiologic analysis of 1,442 children and adolescents registered in the German germ cell tumor protocols.
Schneider DT, Calaminus G, Koch S, Teske C, Schmidt P, Haas RJ, Harms D, Göbel U
Pediatr Blood Cancer 2004 Feb;42(2):169-75. doi: 10.1002/pbc.10321. PMID: 14752882
Germinal testicular tumors in childhood. Report of observations and literature review.
Weissbach L, Altwein JE, Stiens R
Eur Urol 1984;10(2):73-85. doi: 10.1159/000463762. PMID: 6368238

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