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Large cell acanthoma

MedGen UID:
235249
•Concept ID:
C1334362
•
Neoplastic Process
Synonyms: Large Cell Acanthoma; large cell acanthoma
SNOMED CT: Large cell acanthoma (733894009); Large cell acanthoma (1295377001)
 
Monarch Initiative: MONDO:0002961

Definition

A benign, well-circumscribed squamous lesion characterized by the presence of enlarged keratinocytes with nuclei twice the normal size. (WHO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLarge cell acanthoma

Recent clinical studies

Therapy

Large-cell acanthoma.
Weinstock MA
Am J Dermatopathol 1992 Apr;14(2):133-4; discussion 135. doi: 10.1097/00000372-199204000-00007. PMID: 1566973
Large-cell acanthoma is a solar lentigo.
Roewert HJ, Ackerman AB
Am J Dermatopathol 1992 Apr;14(2):122-32. doi: 10.1097/00000372-199204000-00006. PMID: 1533104
Large-cell acanthoma. A distinctive keratosis.
Rabinowitz AD, Inghirami G
Am J Dermatopathol 1992 Apr;14(2):136-8; discussion 139. PMID: 1348913
Multiple large cell acanthomas.
Rabinowitz AD
J Am Acad Dermatol 1983 Jun;8(6):840-5. doi: 10.1016/s0190-9622(83)80014-0. PMID: 6863647

Clinical prediction guides

Large-cell acanthoma of the skin. A study by image analysis cytometry and immunohistochemistry.
Argenyi ZB, Huston BM, Argenyi EE, Maillet MW, Hurt MA
Am J Dermatopathol 1994 Apr;16(2):140-4. doi: 10.1097/00000372-199404000-00006. PMID: 8030765
Achromic verrucous large cell acanthoma.
Ambrojo P, Aguilar A, Requena L, Sánchez Yus E
J Cutan Pathol 1990 Jun;17(3):182-4. doi: 10.1111/j.1600-0560.1990.tb00079.x. PMID: 2373780

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