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Pneumoconiosis

MedGen UID:
19360
•Concept ID:
C0032273
•
Disease or Syndrome
Synonyms: Black lung disease; Coal worker's pneumoconiosis
SNOMED CT: PK - Pneumoconiosis (40122008); Pneumoconiosis (40122008)
 
Monarch Initiative: MONDO:0015926
Orphanet: ORPHA182098

Definition

An occupational lung disorder caused by inhalation of dust particles. It is characterized by bilateral interstitial lung infiltrates. Representative examples include asbestosis, silicosis, anthracosis, and talc pneumoconiosis. [from NCI]

Professional guidelines

PubMed

Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies.
Lurje I, Gaisa NT, Weiskirchen R, Tacke F
Mol Aspects Med 2023 Aug;92:101191. Epub 2023 May 24 doi: 10.1016/j.mam.2023.101191. PMID: 37236017
New Insights into Pathomechanisms and Treatment Possibilities for Lung Silicosis.
Adamcakova J, Mokra D
Int J Mol Sci 2021 Apr 17;22(8) doi: 10.3390/ijms22084162. PMID: 33920534Free PMC Article
Physiopathological considerations in the treatment of coal workers' pneumoconiosis.
Ulmer WT, Baving G, Reichel G
Ann N Y Acad Sci 1972 Dec 29;200:633-42. doi: 10.1111/j.1749-6632.1972.tb40222.x. PMID: 4513333

Recent clinical studies

Etiology

Occupational Lung Diseases: Spectrum of Common Imaging Manifestations.
Matyga AW, Chelala L, Chung JH
Korean J Radiol 2023 Aug;24(8):795-806. doi: 10.3348/kjr.2023.0274. PMID: 37500580Free PMC Article
Inhalational lung diseases.
Prieto Fernandez A, Palomo Antequera B, Del Castillo Arango K, Blanco Guindel M, Nava Tomas ME, Mesa Alvarez AM
Radiologia (Engl Ed) 2022 Dec;64 Suppl 3:290-300. doi: 10.1016/j.rxeng.2022.10.007. PMID: 36737167
Pulmonary talcosis: imaging findings.
Marchiori E, Lourenço S, Gasparetto TD, Zanetti G, Mano CM, Nobre LF
Lung 2010 Apr;188(2):165-71. Epub 2010 Feb 13 doi: 10.1007/s00408-010-9230-y. PMID: 20155272
Miliary lung disease revisited.
Andreu J, Mauleón S, Pallisa E, Majó J, Martinez-Rodriguez M, Cáceres J
Curr Probl Diagn Radiol 2002 Sep-Oct;31(5):189-97. PMID: 12419999
Silica, pneumoconiosis, and carcinoma of the lung.
Heppleston AG
Am J Ind Med 1985;7(4):285-94. doi: 10.1002/ajim.4700070404. PMID: 2986455

Diagnosis

Inhalational lung diseases.
Prieto Fernandez A, Palomo Antequera B, Del Castillo Arango K, Blanco Guindel M, Nava Tomas ME, Mesa Alvarez AM
Radiologia (Engl Ed) 2022 Dec;64 Suppl 3:290-300. doi: 10.1016/j.rxeng.2022.10.007. PMID: 36737167
Pneumoconiosis: current status and future prospects.
Qi XM, Luo Y, Song MY, Liu Y, Shu T, Liu Y, Pang JL, Wang J, Wang C
Chin Med J (Engl) 2021 Apr 13;134(8):898-907. doi: 10.1097/CM9.0000000000001461. PMID: 33879753Free PMC Article
Occupational Lung Disease.
Perlman DM, Maier LA
Med Clin North Am 2019 May;103(3):535-548. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.012. PMID: 30955520
Dental Technicians' Pneumoconiosis.
Okamoto M, Tominaga M, Shimizu S, Yano C, Masuda K, Nakamura M, Zaizen Y, Nouno T, Sakamoto S, Yokoyama M, Kawayama T, Hoshino T
Intern Med 2017 Dec 15;56(24):3323-3326. Epub 2017 Oct 11 doi: 10.2169/internalmedicine.8860-17. PMID: 29021460Free PMC Article
Coal workers' pneumoconiosis.
Lapp NL, Parker JE
Clin Chest Med 1992 Jun;13(2):243-52. PMID: 1511552

Therapy

Occupational Lung Disease.
Perlman DM, Maier LA
Med Clin North Am 2019 May;103(3):535-548. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.012. PMID: 30955520
Dental Technicians' Pneumoconiosis.
Okamoto M, Tominaga M, Shimizu S, Yano C, Masuda K, Nakamura M, Zaizen Y, Nouno T, Sakamoto S, Yokoyama M, Kawayama T, Hoshino T
Intern Med 2017 Dec 15;56(24):3323-3326. Epub 2017 Oct 11 doi: 10.2169/internalmedicine.8860-17. PMID: 29021460Free PMC Article
Occupational lung disease.
Sirajuddin A, Kanne JP
J Thorac Imaging 2009 Nov;24(4):310-20. doi: 10.1097/RTI.0b013e3181c1a9b3. PMID: 19935227
Mica pneumoconiosis.
Davies D, Cotton R
Br J Ind Med 1983 Feb;40(1):22-7. doi: 10.1136/oem.40.1.22. PMID: 6824595Free PMC Article
Pulmonary hypersensitivity reactions.
Ziskind MM, Weill H
Clin Notes Respir Dis 1970 Summer;9(1):3-10. PMID: 4986731

Prognosis

Global incidence, prevalence and disease burden of silicosis: 30 years' overview and forecasted trends.
Liu X, Jiang Q, Wu P, Han L, Zhou P
BMC Public Health 2023 Jul 17;23(1):1366. doi: 10.1186/s12889-023-16295-2. PMID: 37461046Free PMC Article
Pneumoconiosises: modern view.
Babanov SA, Strizhakov LA, Lebedeva MV, Fomin VV, Budash DS, Baikova AG
Ter Arkh 2019 Mar 30;91(3):107-113. doi: 10.26442/00403660.2019.03.000066. PMID: 31094468
Interstitial Lung Diseases in Developing Countries.
Rivera-Ortega P, Molina-Molina M
Ann Glob Health 2019 Jan 22;85(1) doi: 10.5334/aogh.2414. PMID: 30741505Free PMC Article
Respiratory diseases caused by coal mine dust.
Laney AS, Weissman DN
J Occup Environ Med 2014 Oct;56 Suppl 10(0 10):S18-22. doi: 10.1097/JOM.0000000000000260. PMID: 25285970Free PMC Article
Pulmonary talcosis: imaging findings.
Marchiori E, Lourenço S, Gasparetto TD, Zanetti G, Mano CM, Nobre LF
Lung 2010 Apr;188(2):165-71. Epub 2010 Feb 13 doi: 10.1007/s00408-010-9230-y. PMID: 20155272

Clinical prediction guides

Rheumatoid Arthritis in Silica-Exposed Workers.
Min YS, Kim MG, Ahn YS
Int J Environ Res Public Health 2021 Dec 3;18(23) doi: 10.3390/ijerph182312776. PMID: 34886499Free PMC Article
The classic pneumoconioses: new epidemiological and laboratory observations.
Laney AS, Weissman DN
Clin Chest Med 2012 Dec;33(4):745-58. doi: 10.1016/j.ccm.2012.08.005. PMID: 23153613
Pulmonary talcosis: imaging findings.
Marchiori E, Lourenço S, Gasparetto TD, Zanetti G, Mano CM, Nobre LF
Lung 2010 Apr;188(2):165-71. Epub 2010 Feb 13 doi: 10.1007/s00408-010-9230-y. PMID: 20155272
Computed tomography for diagnosis and grading of dust-induced occupational lung disease.
Blum T, Kollmeier J, Ott S, Serke M, Schönfeld N, Bauer T
Curr Opin Pulm Med 2008 Mar;14(2):135-40. doi: 10.1097/MCP.0b013e3282f5248e. PMID: 18303423
Coal workers' pneumoconiosis.
Lapp NL, Parker JE
Clin Chest Med 1992 Jun;13(2):243-52. PMID: 1511552

Recent systematic reviews

The prevalences and levels of occupational exposure to dusts and/or fibres (silica, asbestos and coal): A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury.
Schlünssen V, Mandrioli D, Pega F, Momen NC, Ádám B, Chen W, Cohen RA, Godderis L, Göen T, Hadkhale K, Kunpuek W, Lou J, Mandic-Rajcevic S, Masci F, Nemery B, Popa M, Rajatanavin N, Sgargi D, Siriruttanapruk S, Sun X, Suphanchaimat R, Thammawijaya P, Ujita Y, van der Mierden S, Vangelova K, Ye M, Zungu M, Scheepers PTJ
Environ Int 2023 Aug;178:107980. Epub 2023 May 21 doi: 10.1016/j.envint.2023.107980. PMID: 37487377
Incidence and influencing factors of occupational pneumoconiosis: a systematic review and meta-analysis.
Su X, Kong X, Yu X, Zhang X
BMJ Open 2023 Mar 1;13(3):e065114. doi: 10.1136/bmjopen-2022-065114. PMID: 36858466Free PMC Article
Genetic susceptibility in pneumoconiosis in China: a systematic review.
Chair SY, Chan JYW, Law BMH, Waye MMY, Chien WT
Int Arch Occup Environ Health 2023 Jan;96(1):45-56. Epub 2022 Jul 29 doi: 10.1007/s00420-022-01893-1. PMID: 35906431
Prevalence of coal worker's pneumoconiosis: a systematic review and meta-analysis.
Liu W, Liang R, Zhang R, Wang B, Cao S, Wang X, Ma J, Wang D, Chen W
Environ Sci Pollut Res Int 2022 Dec;29(59):88690-88698. Epub 2022 Jul 14 doi: 10.1007/s11356-022-21966-5. PMID: 35836046
Cancer and mortality in coal mine workers: a systematic review and meta-analysis.
Alif SM, Sim MR, Ho C, Glass DC
Occup Environ Med 2022 May;79(5):347-357. Epub 2021 Nov 15 doi: 10.1136/oemed-2021-107498. PMID: 34782367

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