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Advanced Lung Adenosquamous Carcinoma

MedGen UID:
1793835
•Concept ID:
C5557394
•
Neoplastic Process

Definition

Lung adenosquamous carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Lung Adenosquamous Carcinoma

Professional guidelines

PubMed

Efficacy, safety, and prognostic factors of anlotinib treatment in advanced non-small cell lung cancer patients.
Huang A, Wang W, Qin R, Chen G, Gu A, Han B
J Cancer Res Ther 2022 Sep;18(5):1299-1305. doi: 10.4103/jcrt.jcrt_835_21. PMID: 36204876
Primary lung carcinoma in children and adolescents: An analysis of the European Cooperative Study Group on Paediatric Rare Tumours (EXPeRT).
Abele M, Bajčiová V, Wright F, Behjati S, Voggel S, Schneider DT, Mallebranche C, Česen Mazič M, Guillén G, Krawczyk M, Bień E, Roganovic J, Bisogno G, Chiaravalli S, Ferrari A, Brecht IB, Orbach D, Reguerre Y, Virgone C
Eur J Cancer 2022 Nov;175:19-30. Epub 2022 Sep 7 doi: 10.1016/j.ejca.2022.08.007. PMID: 36087394
Newly Diagnosed Lung Cancer: Which Molecular Tests Are Needed for Optimal Treatment Decision Making?
Ganti AK
Oncology (Williston Park) 2018 Jun;32(6):276-80. PMID: 29940057

Recent clinical studies

Etiology

Genomic landscape of non-small-cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency.
Ashok Kumar P, Graziano SL, Danziger N, Pavlick D, Severson EA, Ramkissoon SH, Huang RSP, Decker B, Ross JS
Cancer Med 2023 Jan;12(2):1157-1166. Epub 2022 Jun 23 doi: 10.1002/cam4.4971. PMID: 35747993Free PMC Article
Efficacy, safety, and prognostic factors of anlotinib treatment in advanced non-small cell lung cancer patients.
Huang A, Wang W, Qin R, Chen G, Gu A, Han B
J Cancer Res Ther 2022 Sep;18(5):1299-1305. doi: 10.4103/jcrt.jcrt_835_21. PMID: 36204876
Primary lung carcinoma in children and adolescents: An analysis of the European Cooperative Study Group on Paediatric Rare Tumours (EXPeRT).
Abele M, Bajčiová V, Wright F, Behjati S, Voggel S, Schneider DT, Mallebranche C, Česen Mazič M, Guillén G, Krawczyk M, Bień E, Roganovic J, Bisogno G, Chiaravalli S, Ferrari A, Brecht IB, Orbach D, Reguerre Y, Virgone C
Eur J Cancer 2022 Nov;175:19-30. Epub 2022 Sep 7 doi: 10.1016/j.ejca.2022.08.007. PMID: 36087394
Immune-Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer With Uncommon Histology.
Manglaviti S, Brambilla M, Signorelli D, Ferrara R, Lo Russo G, Proto C, Galli G, De Toma A, Occhipinti M, Viscardi G, Beninato T, Zattarin E, Bini M, Lobefaro R, Massa G, Bottiglieri A, Apollonio G, Sottotetti E, Di Mauro RM, Trevisan B, Ganzinelli M, Fabbri A, de Braud FGM, Garassino MC, Prelaj A
Clin Lung Cancer 2022 Jan;23(1):e17-e28. Epub 2021 Jul 5 doi: 10.1016/j.cllc.2021.06.013. PMID: 34334296
Neoadjuvant PD-1 Inhibitors and Chemotherapy for Locally Advanced NSCLC: A Retrospective Study.
Chen T, Ning J, Campisi A, Dell'Amore A, Ciarrocchi AP, Li Z, Song L, Huang J, Yang Y, Stella F, Luo Q
Ann Thorac Surg 2022 Mar;113(3):993-999. Epub 2021 Mar 26 doi: 10.1016/j.athoracsur.2021.03.041. PMID: 33781737

Diagnosis

Primary lung carcinoma in children and adolescents: An analysis of the European Cooperative Study Group on Paediatric Rare Tumours (EXPeRT).
Abele M, Bajčiová V, Wright F, Behjati S, Voggel S, Schneider DT, Mallebranche C, Česen Mazič M, Guillén G, Krawczyk M, Bień E, Roganovic J, Bisogno G, Chiaravalli S, Ferrari A, Brecht IB, Orbach D, Reguerre Y, Virgone C
Eur J Cancer 2022 Nov;175:19-30. Epub 2022 Sep 7 doi: 10.1016/j.ejca.2022.08.007. PMID: 36087394
Neoadjuvant ceritinib treatment in ALK-rearranged locally advanced adenosquamous carcinoma: A case report.
Mai S, Wang Y, Wang X, Yang W, Gao H, Xu Z, Xu L, Xu L, Ou Q, Chen H, Wang Z
Thorac Cancer 2022 Aug;13(15):2275-2278. Epub 2022 Jul 12 doi: 10.1111/1759-7714.14558. PMID: 35818908Free PMC Article
Hypercalcemia-Leukocytosis syndrome and adenosquamous lung carcinoma: An overlooked conjugation.
Oliveira Pereira J, Gama J, Ferreira D, Santos A
Oncol Res 2021;29(2):81-85. Epub 2022 Jul 13 doi: 10.32604/or.2022.023450. PMID: 37305400Free PMC Article
Lung Cancer in the Young.
Galvez-Nino M, Ruiz R, Pinto JA, Roque K, Mantilla R, Raez LE, Mas L
Lung 2020 Feb;198(1):195-200. Epub 2019 Nov 26 doi: 10.1007/s00408-019-00294-5. PMID: 31773258
Pathology of lung cancer.
Travis WD
Clin Chest Med 2011 Dec;32(4):669-92. doi: 10.1016/j.ccm.2011.08.005. PMID: 22054879

Therapy

Subtyping of advanced lung cancer based on PD-L1 expression, tumor histopathology and mutation burden (EGFR and KRAS): a study from North India.
Kulshrestha R, Saxena H, Kumar R, Spalgais S, Mrigpuri P, Goel N, Menon B, Rani M, Mahor P, Bhutani I
Monaldi Arch Chest Dis 2023 Feb 1;93(4) doi: 10.4081/monaldi.2023.2449. PMID: 36723380
Efficacy, safety, and prognostic factors of anlotinib treatment in advanced non-small cell lung cancer patients.
Huang A, Wang W, Qin R, Chen G, Gu A, Han B
J Cancer Res Ther 2022 Sep;18(5):1299-1305. doi: 10.4103/jcrt.jcrt_835_21. PMID: 36204876
Neoadjuvant ceritinib treatment in ALK-rearranged locally advanced adenosquamous carcinoma: A case report.
Mai S, Wang Y, Wang X, Yang W, Gao H, Xu Z, Xu L, Xu L, Ou Q, Chen H, Wang Z
Thorac Cancer 2022 Aug;13(15):2275-2278. Epub 2022 Jul 12 doi: 10.1111/1759-7714.14558. PMID: 35818908Free PMC Article
Neoadjuvant PD-1 Inhibitors and Chemotherapy for Locally Advanced NSCLC: A Retrospective Study.
Chen T, Ning J, Campisi A, Dell'Amore A, Ciarrocchi AP, Li Z, Song L, Huang J, Yang Y, Stella F, Luo Q
Ann Thorac Surg 2022 Mar;113(3):993-999. Epub 2021 Mar 26 doi: 10.1016/j.athoracsur.2021.03.041. PMID: 33781737
Therapeutic efficacy of gefitinib and erlotinib in patients with advanced lung adenosquamous carcinoma.
Song Z, Lin B, Shao L, Zhang Y
J Chin Med Assoc 2013 Sep;76(9):481-5. Epub 2013 Jun 13 doi: 10.1016/j.jcma.2013.05.007. PMID: 23769878

Prognosis

Genomic landscape of non-small-cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency.
Ashok Kumar P, Graziano SL, Danziger N, Pavlick D, Severson EA, Ramkissoon SH, Huang RSP, Decker B, Ross JS
Cancer Med 2023 Jan;12(2):1157-1166. Epub 2022 Jun 23 doi: 10.1002/cam4.4971. PMID: 35747993Free PMC Article
Efficacy, safety, and prognostic factors of anlotinib treatment in advanced non-small cell lung cancer patients.
Huang A, Wang W, Qin R, Chen G, Gu A, Han B
J Cancer Res Ther 2022 Sep;18(5):1299-1305. doi: 10.4103/jcrt.jcrt_835_21. PMID: 36204876
Primary lung carcinoma in children and adolescents: An analysis of the European Cooperative Study Group on Paediatric Rare Tumours (EXPeRT).
Abele M, Bajčiová V, Wright F, Behjati S, Voggel S, Schneider DT, Mallebranche C, Česen Mazič M, Guillén G, Krawczyk M, Bień E, Roganovic J, Bisogno G, Chiaravalli S, Ferrari A, Brecht IB, Orbach D, Reguerre Y, Virgone C
Eur J Cancer 2022 Nov;175:19-30. Epub 2022 Sep 7 doi: 10.1016/j.ejca.2022.08.007. PMID: 36087394
Hypercalcemia-Leukocytosis syndrome and adenosquamous lung carcinoma: An overlooked conjugation.
Oliveira Pereira J, Gama J, Ferreira D, Santos A
Oncol Res 2021;29(2):81-85. Epub 2022 Jul 13 doi: 10.32604/or.2022.023450. PMID: 37305400Free PMC Article
Lung Cancer in the Young.
Galvez-Nino M, Ruiz R, Pinto JA, Roque K, Mantilla R, Raez LE, Mas L
Lung 2020 Feb;198(1):195-200. Epub 2019 Nov 26 doi: 10.1007/s00408-019-00294-5. PMID: 31773258

Clinical prediction guides

Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation.
Fang Z, Han X, Chen Y, Tong X, Xue Y, Yao S, Tang S, Pan Y, Sun Y, Wang X, Jin Y, Chen H, Hu L, Hui L, Li L, Chen L, Ji H
Signal Transduct Target Ther 2023 Jan 11;8(1):16. doi: 10.1038/s41392-022-01227-0. PMID: 36627278Free PMC Article
Genomic landscape of non-small-cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency.
Ashok Kumar P, Graziano SL, Danziger N, Pavlick D, Severson EA, Ramkissoon SH, Huang RSP, Decker B, Ross JS
Cancer Med 2023 Jan;12(2):1157-1166. Epub 2022 Jun 23 doi: 10.1002/cam4.4971. PMID: 35747993Free PMC Article
Efficacy, safety, and prognostic factors of anlotinib treatment in advanced non-small cell lung cancer patients.
Huang A, Wang W, Qin R, Chen G, Gu A, Han B
J Cancer Res Ther 2022 Sep;18(5):1299-1305. doi: 10.4103/jcrt.jcrt_835_21. PMID: 36204876
Molecular and expressional characterization of tumor heterogeneity in pulmonary carcinosarcoma.
Ohtaki Y, Kawabata-Iwakawa R, Nobusawa S, Goto Y, Shimizu K, Yajima T, Nakazawa S, Kawatani N, Yoshida Y, Sano T, Shirabe K
Mol Carcinog 2022 Oct;61(10):924-932. Epub 2022 Jul 18 doi: 10.1002/mc.23448. PMID: 35848137
Incidence and risk factors for the development of cerebral metastasis in cervical cancer patients.
Rangel JB, Giglio AG, Cardozo CL, Bergmann A, Thuler LCS
J Gynecol Oncol 2022 Sep;33(5):e58. Epub 2022 Jun 8 doi: 10.3802/jgo.2022.33.e58. PMID: 35712971Free PMC Article

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