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Locally Advanced Transitional Cell Carcinoma

MedGen UID:
1781330
•Concept ID:
C5446570
•
Neoplastic Process

Definition

Transitional cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Long-term survival after gemcitabine and cisplatin in patients with locally advanced transitional cell carcinoma of the bladder: focus on supplementary treatment strategies.
Als AB, Sengelov L, von der Maase H
Eur Urol 2007 Aug;52(2):478-86. Epub 2007 Mar 15 doi: 10.1016/j.eururo.2007.03.016. PMID: 17383078
Neoadjuvant intra-arterial doxorubicin chemotherapy in combination with low dose radiotherapy for the treatment of locally advanced transitional cell carcinoma of the bladder.
Sumiyoshi Y, Yokota K, Akiyama M, Inoue Y, Yoneda F, Tsujimura H, Nakajima M, Yokozeki H, Maebayashi K
J Urol 1994 Aug;152(2 Pt 1):362-6. doi: 10.1016/s0022-5347(17)32740-4. PMID: 8015072
Experiences with continuous intraarterial administration of recombinant interferon alpha-2C (rIFN-alpha 2) for treatment of patients with advanced transitional cell bladder cancer.
Scheithauer W, Theyer G, Zechner O, Ludwig H
J Biol Regul Homeost Agents 1988 Apr-Jun;2(2):67-70. PMID: 3188978

Recent clinical studies

Etiology

Adjuvant Chemotherapy With Gemcitabine Plus Cisplatin for Kidney Transplant Patients With Locally Advanced Transitional Cell Carcinoma: A Single-center Experience.
Wang ZP, Wang WY, Zhu YC, Xiao J, Lin J, Guo YW, Tian Y
Transplant Proc 2016 Jul-Aug;48(6):2076-9. doi: 10.1016/j.transproceed.2016.02.075. PMID: 27569947
Efficacy of adjuvant gemcitabine-cisplatin chemotherapy: a comparative study between locally advanced transitional cell carcinoma of the bladder and upper urinary tract.
Song YS, Cho JS, Cho KS, Doo SH, Chung BH, Kim SJ, Yang WJ, Song KH, Kim CI, Hong SJ
Urol Int 2010;85(1):47-51. Epub 2010 Mar 16 doi: 10.1159/000296294. PMID: 20234122
Neoadjuvant and adjuvant chemotherapy in muscle-invasive bladder cancer.
Calabrò F, Sternberg CN
Eur Urol 2009 Feb;55(2):348-58. Epub 2008 Oct 16 doi: 10.1016/j.eururo.2008.10.016. PMID: 18977070
Perioperative chemotherapy for bladder cancer.
Sonpavde G, Petrylak DP
Crit Rev Oncol Hematol 2006 Feb;57(2):133-44. Epub 2005 Jun 28 doi: 10.1016/j.critrevonc.2005.05.004. PMID: 15990329
Results of radical cystectomy for transitional cell carcinoma of the bladder and the effect of chemotherapy.
Soloway MS, Lopez AE, Patel J, Lu Y
Cancer 1994 Apr 1;73(7):1926-31. doi: 10.1002/1097-0142(19940401)73:7<1926::aid-cncr2820730725>3.0.co;2-q. PMID: 8137219

Diagnosis

Adjuvant intraoperative electron radiotherapy and external beam radiotherapy for locally advanced transitional cell carcinoma of the ureter.
Zhang Q, Fu S, Liu T, Peng L, Huang G, Lu JJ
Urol Oncol 2009 Jan-Feb;27(1):14-20. Epub 2008 Jan 14 doi: 10.1016/j.urolonc.2007.07.019. PMID: 18367127
Adjuvant radiotherapy with and without concurrent chemotherapy for locally advanced transitional cell carcinoma of the renal pelvis and ureter.
Czito B, Zietman A, Kaufman D, Skowronski U, Shipley W
J Urol 2004 Oct;172(4 Pt 1):1271-5. doi: 10.1097/01.ju.0000137910.38441.8a. PMID: 15371822
Neoadjuvant chemotherapy for invasive bladder carcinoma: disease outcome and bladder preservation and relationship to local tumor response.
Hatcher PA, Hahn RG, Richardson RL, Zincke H
Eur Urol 1994;25(3):209-15. doi: 10.1159/000475285. PMID: 8200403

Therapy

Adjuvant Chemotherapy With Gemcitabine Plus Cisplatin for Kidney Transplant Patients With Locally Advanced Transitional Cell Carcinoma: A Single-center Experience.
Wang ZP, Wang WY, Zhu YC, Xiao J, Lin J, Guo YW, Tian Y
Transplant Proc 2016 Jul-Aug;48(6):2076-9. doi: 10.1016/j.transproceed.2016.02.075. PMID: 27569947
Efficacy of adjuvant gemcitabine-cisplatin chemotherapy: a comparative study between locally advanced transitional cell carcinoma of the bladder and upper urinary tract.
Song YS, Cho JS, Cho KS, Doo SH, Chung BH, Kim SJ, Yang WJ, Song KH, Kim CI, Hong SJ
Urol Int 2010;85(1):47-51. Epub 2010 Mar 16 doi: 10.1159/000296294. PMID: 20234122
Neoadjuvant and adjuvant chemotherapy in muscle-invasive bladder cancer.
Calabrò F, Sternberg CN
Eur Urol 2009 Feb;55(2):348-58. Epub 2008 Oct 16 doi: 10.1016/j.eururo.2008.10.016. PMID: 18977070
Perioperative chemotherapy for bladder cancer.
Sonpavde G, Petrylak DP
Crit Rev Oncol Hematol 2006 Feb;57(2):133-44. Epub 2005 Jun 28 doi: 10.1016/j.critrevonc.2005.05.004. PMID: 15990329
Results of radical cystectomy for transitional cell carcinoma of the bladder and the effect of chemotherapy.
Soloway MS, Lopez AE, Patel J, Lu Y
Cancer 1994 Apr 1;73(7):1926-31. doi: 10.1002/1097-0142(19940401)73:7<1926::aid-cncr2820730725>3.0.co;2-q. PMID: 8137219

Prognosis

Adjuvant Chemotherapy With Gemcitabine Plus Cisplatin for Kidney Transplant Patients With Locally Advanced Transitional Cell Carcinoma: A Single-center Experience.
Wang ZP, Wang WY, Zhu YC, Xiao J, Lin J, Guo YW, Tian Y
Transplant Proc 2016 Jul-Aug;48(6):2076-9. doi: 10.1016/j.transproceed.2016.02.075. PMID: 27569947
Efficacy of adjuvant gemcitabine-cisplatin chemotherapy: a comparative study between locally advanced transitional cell carcinoma of the bladder and upper urinary tract.
Song YS, Cho JS, Cho KS, Doo SH, Chung BH, Kim SJ, Yang WJ, Song KH, Kim CI, Hong SJ
Urol Int 2010;85(1):47-51. Epub 2010 Mar 16 doi: 10.1159/000296294. PMID: 20234122
Chemotherapy with gemcitabine, paclitaxel, and cisplatin in the treatment of patients with advanced transitional cell carcinoma of the urothelium.
Ecke TH, Bartel P, Koch S, Ruttloff J, Theissig F
Oncol Rep 2006 Dec;16(6):1381-8. PMID: 17089065
Results of radical cystectomy for transitional cell carcinoma of the bladder and the effect of chemotherapy.
Soloway MS, Lopez AE, Patel J, Lu Y
Cancer 1994 Apr 1;73(7):1926-31. doi: 10.1002/1097-0142(19940401)73:7<1926::aid-cncr2820730725>3.0.co;2-q. PMID: 8137219
Neoadjuvant intra-arterial doxorubicin chemotherapy in combination with low dose radiotherapy for the treatment of locally advanced transitional cell carcinoma of the bladder.
Sumiyoshi Y, Yokota K, Akiyama M, Inoue Y, Yoneda F, Tsujimura H, Nakajima M, Yokozeki H, Maebayashi K
J Urol 1994 Aug;152(2 Pt 1):362-6. doi: 10.1016/s0022-5347(17)32740-4. PMID: 8015072

Clinical prediction guides

Adjuvant Chemotherapy With Gemcitabine Plus Cisplatin for Kidney Transplant Patients With Locally Advanced Transitional Cell Carcinoma: A Single-center Experience.
Wang ZP, Wang WY, Zhu YC, Xiao J, Lin J, Guo YW, Tian Y
Transplant Proc 2016 Jul-Aug;48(6):2076-9. doi: 10.1016/j.transproceed.2016.02.075. PMID: 27569947
Chemotherapy with gemcitabine, paclitaxel, and cisplatin in the treatment of patients with advanced transitional cell carcinoma of the urothelium.
Ecke TH, Bartel P, Koch S, Ruttloff J, Theissig F
Oncol Rep 2006 Dec;16(6):1381-8. PMID: 17089065
A phase II study of gemcitabine and docetaxel therapy in patients with advanced urothelial carcinoma.
Gitlitz BJ, Baker C, Chapman Y, Allen HJ, Bosserman LD, Patel R, Sanchez JD, Shapiro RM, Figlin RA
Cancer 2003 Nov 1;98(9):1863-9. doi: 10.1002/cncr.11726. PMID: 14584068
Results of radical cystectomy for transitional cell carcinoma of the bladder and the effect of chemotherapy.
Soloway MS, Lopez AE, Patel J, Lu Y
Cancer 1994 Apr 1;73(7):1926-31. doi: 10.1002/1097-0142(19940401)73:7<1926::aid-cncr2820730725>3.0.co;2-q. PMID: 8137219
Neoadjuvant intra-arterial doxorubicin chemotherapy in combination with low dose radiotherapy for the treatment of locally advanced transitional cell carcinoma of the bladder.
Sumiyoshi Y, Yokota K, Akiyama M, Inoue Y, Yoneda F, Tsujimura H, Nakajima M, Yokozeki H, Maebayashi K
J Urol 1994 Aug;152(2 Pt 1):362-6. doi: 10.1016/s0022-5347(17)32740-4. PMID: 8015072

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