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COVID-19-Associated Nervous System Disorder

MedGen UID:: 1776032
•Concept ID:: C5419165
•: Disease or Syndrome

Synonym:

SARS-CoV-2 -Associated Nervous System Disorder

Definition

A central or peripheral nervous system disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVCOVID-19-Associated Nervous System Disorder

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease Attributes
    - Infectious disease
      - Infectious Disorder by Site
        Infectious disease of the nervous system
        COVID-19-Associated Nervous System Disorder
        COVID-19-Associated Ataxia
        COVID-19-Associated Encephalitis
        COVID-19-Associated Acute Hemorrhagic Necrotizing Encephalitis
        COVID-19-Associated Stroke
        COVID-19-Associated Trigeminal Neuralgia

Professional guidelines

PubMed

Treatment of COVID-19 Associated Olfactory Dysfunction: A Systematic Review.

Bischoff S, Moyaert M, Clijsters M, Vanderbroek A, Van Gerven L
Curr Allergy Asthma Rep 2024 Oct 31;25(1):2. doi: 10.1007/s11882-024-01182-6. PMID: 39477832 Free PMC Article

Headache associated with COVID-19: Epidemiology, characteristics, pathophysiology, and management.

Sampaio Rocha-Filho PA
Headache 2022 Jun;62(6):650-656. Epub 2022 May 11 doi: 10.1111/head.14319. PMID: 35545780 Free PMC Article

Mucormycosis in COVID-19 patients: predisposing factors, prevention and management.

Rudrabhatla PK, Reghukumar A, Thomas SV
Acta Neurol Belg 2022 Apr;122(2):273-280. Epub 2021 Nov 24 doi: 10.1007/s13760-021-01840-w. PMID: 34820787 Free PMC Article

See all (16)

Recent clinical studies

Etiology

COVID-19 and Cerebrovascular Disease.

Catherine C, Veitinger J, Chou SH
Semin Neurol 2023 Apr;43(2):219-228. Epub 2023 May 22 doi: 10.1055/s-0043-1768475. PMID: 37216977

Malnutrition and Sarcopenia in COVID-19 Survivors.

Grund S, Bauer JM
Clin Geriatr Med 2022 Aug;38(3):559-564. Epub 2022 Apr 21 doi: 10.1016/j.cger.2022.04.001. PMID: 35868673 Free PMC Article

Neurological Sequelae of COVID-19.

Ahmad SJ, Feigen CM, Vazquez JP, Kobets AJ, Altschul DJ
J Integr Neurosci 2022 Apr 6;21(3):77. doi: 10.31083/j.jin2103077. PMID: 35633158

COVID-19 associated cognitive impairment: A systematic review.

Tavares-Júnior JWL, de Souza ACC, Borges JWP, Oliveira DN, Siqueira-Neto JI, Sobreira-Neto MA, Braga-Neto P
Cortex 2022 Jul;152:77-97. Epub 2022 Apr 18 doi: 10.1016/j.cortex.2022.04.006. PMID: 35537236 Free PMC Article

Stroke in COVID-19: A systematic review and meta-analysis.

Nannoni S, de Groot R, Bell S, Markus HS
Int J Stroke 2021 Feb;16(2):137-149. Epub 2020 Nov 11 doi: 10.1177/1747493020972922. PMID: 33103610 Free PMC Article

See all (171)

Diagnosis

Atypical COVID-19-associated Non-convulsive Status Epilepticus case.

Ioshpa M
Isr Med Assoc J 2023 Oct;25(10):662-663. PMID: 37846992

COVID-19-Associated Chemosensory Loss Continues to Decline.

Reiter ER, Coelho DH, French E, Costanzo RM; N3C Consortium
Otolaryngol Head Neck Surg 2023 Nov;169(5):1386-1389. Epub 2023 May 26 doi: 10.1002/ohn.384. PMID: 37232470 Free PMC Article

COVID-19 associated myopathy.

Aschman T, Stenzel W
Curr Opin Neurol 2022 Oct 1;35(5):622-628. Epub 2022 Aug 11 doi: 10.1097/WCO.0000000000001101. PMID: 35950722

Malnutrition and Sarcopenia in COVID-19 Survivors.

Grund S, Bauer JM
Clin Geriatr Med 2022 Aug;38(3):559-564. Epub 2022 Apr 21 doi: 10.1016/j.cger.2022.04.001. PMID: 35868673 Free PMC Article

Cardiovascular complications of COVID-19.

Farshidfar F, Koleini N, Ardehali H
JCI Insight 2021 Jul 8;6(13) doi: 10.1172/jci.insight.148980. PMID: 34061779 Free PMC Article

See all (196)

Therapy

Atypical COVID-19-associated Non-convulsive Status Epilepticus case.

Ioshpa M
Isr Med Assoc J 2023 Oct;25(10):662-663. PMID: 37846992

COVID-19-Associated Benzodiazepine-Resistant Catatonia Responds to Amantadine.

Oh J, Amber-Monta K, Sahota PC, Pradhan BK, Koola MM
Prim Care Companion CNS Disord 2022 Nov 17;24(6) doi: 10.4088/PCC.22cr03394. PMID: 36399386

COVID-19 and the peripheral nervous system. A 2-year review from the pandemic to the vaccine era.

Taga A, Lauria G
J Peripher Nerv Syst 2022 Mar;27(1):4-30. Epub 2022 Mar 14 doi: 10.1111/jns.12482. PMID: 35137496 Free PMC Article

Cerebral venous thrombosis in COVID-19.

Ghosh R, Roy D, Mandal A, Pal SK, Chandra Swaika B, Naga D, Pandit A, Ray BK, Benito-León J
Diabetes Metab Syndr 2021 May-Jun;15(3):1039-1045. Epub 2021 May 18 doi: 10.1016/j.dsx.2021.04.026. PMID: 34015627 Free PMC Article

Stroke in COVID-19: A systematic review and meta-analysis.

Nannoni S, de Groot R, Bell S, Markus HS
Int J Stroke 2021 Feb;16(2):137-149. Epub 2020 Nov 11 doi: 10.1177/1747493020972922. PMID: 33103610 Free PMC Article

See all (81)

Prognosis

COVID-19-Associated Chemosensory Loss Continues to Decline.

Reiter ER, Coelho DH, French E, Costanzo RM; N3C Consortium
Otolaryngol Head Neck Surg 2023 Nov;169(5):1386-1389. Epub 2023 May 26 doi: 10.1002/ohn.384. PMID: 37232470 Free PMC Article

COVID-19 and Cerebrovascular Disease.

Catherine C, Veitinger J, Chou SH
Semin Neurol 2023 Apr;43(2):219-228. Epub 2023 May 22 doi: 10.1055/s-0043-1768475. PMID: 37216977

Proteomic and phosphoproteomic characteristics of the cortex, hippocampus, thalamus, lung, and kidney in COVID-19-infected female K18-hACE2 mice.

Liu JF, Peng WJ, Wu Y, Yang YH, Wu SF, Liu DP, Liu JN, Yang JT
EBioMedicine 2023 Apr;90:104518. Epub 2023 Mar 16 doi: 10.1016/j.ebiom.2023.104518. PMID: 36933413 Free PMC Article

Neurological manifestations of COVID-19: available evidences and a new paradigm.

Khatoon F, Prasad K, Kumar V
J Neurovirol 2020 Oct;26(5):619-630. Epub 2020 Aug 24 doi: 10.1007/s13365-020-00895-4. PMID: 32839951 Free PMC Article

COVID-19-associated Guillain-Barré syndrome: The early pandemic experience.

Caress JB, Castoro RJ, Simmons Z, Scelsa SN, Lewis RA, Ahlawat A, Narayanaswami P
Muscle Nerve 2020 Oct;62(4):485-491. Epub 2020 Aug 11 doi: 10.1002/mus.27024. PMID: 32678460 Free PMC Article

See all (109)

Clinical prediction guides

COVID-19-Associated Chemosensory Loss Continues to Decline.

Reiter ER, Coelho DH, French E, Costanzo RM; N3C Consortium
Otolaryngol Head Neck Surg 2023 Nov;169(5):1386-1389. Epub 2023 May 26 doi: 10.1002/ohn.384. PMID: 37232470 Free PMC Article

Proteomic and phosphoproteomic characteristics of the cortex, hippocampus, thalamus, lung, and kidney in COVID-19-infected female K18-hACE2 mice.

Liu JF, Peng WJ, Wu Y, Yang YH, Wu SF, Liu DP, Liu JN, Yang JT
EBioMedicine 2023 Apr;90:104518. Epub 2023 Mar 16 doi: 10.1016/j.ebiom.2023.104518. PMID: 36933413 Free PMC Article

COVID-19 associated cognitive impairment: A systematic review.

COVID-19 associated nervous system manifestations.

Khatoon F, Prasad K, Kumar V
Sleep Med 2022 Mar;91:231-236. Epub 2021 Jul 9 doi: 10.1016/j.sleep.2021.07.005. PMID: 34321155 Free PMC Article

Cardiovascular complications of COVID-19.

Farshidfar F, Koleini N, Ardehali H
JCI Insight 2021 Jul 8;6(13) doi: 10.1172/jci.insight.148980. PMID: 34061779 Free PMC Article

See all (119)

Recent systematic reviews

COVID-19 associated cognitive impairment: A systematic review.

COVID-19 associated cranial nerve neuropathy: A systematic review.

Finsterer J, Scorza FA, Scorza C, Fiorini A
Bosn J Basic Med Sci 2022 Feb 1;22(1):39-45. doi: 10.17305/bjbms.2021.6341. PMID: 34392827 Free PMC Article

Rhino-orbital-cerebral-mucormycosis in COVID-19: A systematic review.

Bhattacharyya A, Sarma P, Sharma DJ, Das KK, Kaur H, Prajapat M, Kumar S, Bansal S, Prakash A, Avti P, Thota P, Reddy DH, Gautam BS, Medhi B
Indian J Pharmacol 2021 Jul-Aug;53(4):317-327. doi: 10.4103/ijp.ijp_419_21. PMID: 34414911 Free PMC Article

Status epilepticus and COVID-19: A systematic review.

Dono F, Nucera B, Lanzone J, Evangelista G, Rinaldi F, Speranza R, Troisi S, Tinti L, Russo M, Di Pietro M, Onofrj M, Bonanni L, Assenza G, Vollono C, Anzellotti F, Brigo F
Epilepsy Behav 2021 May;118:107887. Epub 2021 Mar 17 doi: 10.1016/j.yebeh.2021.107887. PMID: 33743344 Free PMC Article

Stroke in COVID-19: A systematic review and meta-analysis.

Nannoni S, de Groot R, Bell S, Markus HS
Int J Stroke 2021 Feb;16(2):137-149. Epub 2020 Nov 11 doi: 10.1177/1747493020972922. PMID: 33103610 Free PMC Article

See all (28)

MedGen

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COVID-19-Associated Nervous System Disorder

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity