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Refractory Vaginal Carcinoma

MedGen UID:
1741029
•Concept ID:
C5420822
•
Neoplastic Process

Definition

Vaginal carcinoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Vaginal Carcinoma

Professional guidelines

PubMed

SOGC clinical guidelines. Hysterectomy.
Lefebvre G, Allaire C, Jeffrey J, Vilos G, Arneja J, Birch C, Fortier M; Clinical Practice Gynaecology Committee and Executive Committeee and Council, Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2002 Jan;24(1):37-61; quiz 74-6. PMID: 12196887
Recurrent stage I endometrial carcinoma: results of treatment and prognostic factors.
Mandell LR, Nori D, Hilaris B
Int J Radiat Oncol Biol Phys 1985 Jun;11(6):1103-9. doi: 10.1016/0360-3016(85)90056-2. PMID: 3997592

Recent clinical studies

Etiology

Intracardiac metastasis of gestational choriocarcinoma: a case report and literature review.
Gu Y, Zheng H, Xue X, Wang D, Cheng H, Zong L, Xiang Y
BMC Pregnancy Childbirth 2024 Jan 2;24(1):19. doi: 10.1186/s12884-023-06144-w. PMID: 38166849Free PMC Article
Human papillomavirus-related genital disease in the immunocompromised host: Part II.
Gormley RH, Kovarik CL
J Am Acad Dermatol 2012 Jun;66(6):883.e1-17; quiz 899-900. doi: 10.1016/j.jaad.2010.12.049. PMID: 22583721
SOGC clinical guidelines. Hysterectomy.
Lefebvre G, Allaire C, Jeffrey J, Vilos G, Arneja J, Birch C, Fortier M; Clinical Practice Gynaecology Committee and Executive Committeee and Council, Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2002 Jan;24(1):37-61; quiz 74-6. PMID: 12196887
Local radiation therapy for localized relapsed or refractory ovarian cancer patients with or without symptoms after chemotherapy.
Fujiwara K, Suzuki S, Yoden E, Ishikawa H, Imajo Y, Kohno I
Int J Gynecol Cancer 2002 May-Jun;12(3):250-6. doi: 10.1046/j.1525-1438.2002.01096.x. PMID: 12060445
Polymyositis and vaginal carcinoma.
Cormio G, Di Vagno G, Loverro G, Selvaggi L
Arch Gynecol Obstet 1993;253(3):145-7. doi: 10.1007/BF02767332. PMID: 8250602

Diagnosis

Intracardiac metastasis of gestational choriocarcinoma: a case report and literature review.
Gu Y, Zheng H, Xue X, Wang D, Cheng H, Zong L, Xiang Y
BMC Pregnancy Childbirth 2024 Jan 2;24(1):19. doi: 10.1186/s12884-023-06144-w. PMID: 38166849Free PMC Article
Immune Checkpoint Blockade in PD-L1-Positive Platinum-Refractory Cervical Carcinoma.
Tewari KS
J Clin Oncol 2019 Jun 10;37(17):1449-1454. Epub 2019 Apr 26 doi: 10.1200/JCO.19.00119. PMID: 31026210
Uterine serous carcinoma: Reassessing effectiveness of platinum-based adjuvant therapy.
Tortorella L, Langstraat CL, Weaver AL, McGree ME, Bakkum-Gamez JN, Dowdy SC, Cliby WA, Keeney GL, Sherman ME, Weroha SJ, Mariani A, Podratz KC
Gynecol Oncol 2018 May;149(2):291-296. Epub 2018 Mar 14 doi: 10.1016/j.ygyno.2018.02.022. PMID: 29550183
Idiopathic CD4 lymphocytopenia manifesting as refractory genital dysplasia.
Allard JE, Lee RU
Obstet Gynecol 2013 Aug;122(2 Pt 2):455-458. doi: 10.1097/AOG.0b013e3182835850. PMID: 23884258
Human immunodeficiency virus and AIDS. 1993 update.
Cohn JA
J Nurse Midwifery 1993 Mar-Apr;38(2):65-85. doi: 10.1016/0091-2182(93)90140-c. PMID: 8388055

Therapy

Immune Checkpoint Blockade in PD-L1-Positive Platinum-Refractory Cervical Carcinoma.
Tewari KS
J Clin Oncol 2019 Jun 10;37(17):1449-1454. Epub 2019 Apr 26 doi: 10.1200/JCO.19.00119. PMID: 31026210
Human papillomavirus-related genital disease in the immunocompromised host: Part II.
Gormley RH, Kovarik CL
J Am Acad Dermatol 2012 Jun;66(6):883.e1-17; quiz 899-900. doi: 10.1016/j.jaad.2010.12.049. PMID: 22583721
Vaginal intraepithelial neoplasia (VAIN) after radiation therapy for gynecologic malignancies: a clinically recalcitrant entity.
Liao JB, Jean S, Wilkinson-Ryan I, Ford AE, Tanyi JL, Hagemann AR, Lin LL, McGrath CM, Rubin SC
Gynecol Oncol 2011 Jan;120(1):108-12. doi: 10.1016/j.ygyno.2010.09.005. PMID: 20937524
SOGC clinical guidelines. Hysterectomy.
Lefebvre G, Allaire C, Jeffrey J, Vilos G, Arneja J, Birch C, Fortier M; Clinical Practice Gynaecology Committee and Executive Committeee and Council, Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2002 Jan;24(1):37-61; quiz 74-6. PMID: 12196887
Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7.
Steller MA, Gurski KJ, Murakami M, Daniel RW, Shah KV, Celis E, Sette A, Trimble EL, Park RC, Marincola FM
Clin Cancer Res 1998 Sep;4(9):2103-9. PMID: 9748126

Prognosis

Intracardiac metastasis of gestational choriocarcinoma: a case report and literature review.
Gu Y, Zheng H, Xue X, Wang D, Cheng H, Zong L, Xiang Y
BMC Pregnancy Childbirth 2024 Jan 2;24(1):19. doi: 10.1186/s12884-023-06144-w. PMID: 38166849Free PMC Article
SOGC clinical guidelines. Hysterectomy.
Lefebvre G, Allaire C, Jeffrey J, Vilos G, Arneja J, Birch C, Fortier M; Clinical Practice Gynaecology Committee and Executive Committeee and Council, Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2002 Jan;24(1):37-61; quiz 74-6. PMID: 12196887
Local radiation therapy for localized relapsed or refractory ovarian cancer patients with or without symptoms after chemotherapy.
Fujiwara K, Suzuki S, Yoden E, Ishikawa H, Imajo Y, Kohno I
Int J Gynecol Cancer 2002 May-Jun;12(3):250-6. doi: 10.1046/j.1525-1438.2002.01096.x. PMID: 12060445
Polymyositis and vaginal carcinoma.
Cormio G, Di Vagno G, Loverro G, Selvaggi L
Arch Gynecol Obstet 1993;253(3):145-7. doi: 10.1007/BF02767332. PMID: 8250602
Recurrent stage I endometrial carcinoma: results of treatment and prognostic factors.
Mandell LR, Nori D, Hilaris B
Int J Radiat Oncol Biol Phys 1985 Jun;11(6):1103-9. doi: 10.1016/0360-3016(85)90056-2. PMID: 3997592

Clinical prediction guides

Intracardiac metastasis of gestational choriocarcinoma: a case report and literature review.
Gu Y, Zheng H, Xue X, Wang D, Cheng H, Zong L, Xiang Y
BMC Pregnancy Childbirth 2024 Jan 2;24(1):19. doi: 10.1186/s12884-023-06144-w. PMID: 38166849Free PMC Article
New concept in urologic surgery: The total extended genital sparing radical cystectomy in women.
Cisternino A, Capone L, Rosati A, Latiano C, Sebastio N, Colella A, Cretì G
Arch Ital Urol Androl 2023 May 22;95(2):11058. doi: 10.4081/aiua.2023.11058. PMID: 37212881
Uterine serous carcinoma: Reassessing effectiveness of platinum-based adjuvant therapy.
Tortorella L, Langstraat CL, Weaver AL, McGree ME, Bakkum-Gamez JN, Dowdy SC, Cliby WA, Keeney GL, Sherman ME, Weroha SJ, Mariani A, Podratz KC
Gynecol Oncol 2018 May;149(2):291-296. Epub 2018 Mar 14 doi: 10.1016/j.ygyno.2018.02.022. PMID: 29550183
SOGC clinical guidelines. Hysterectomy.
Lefebvre G, Allaire C, Jeffrey J, Vilos G, Arneja J, Birch C, Fortier M; Clinical Practice Gynaecology Committee and Executive Committeee and Council, Society of Obstetricians and Gynaecologists of Canada
J Obstet Gynaecol Can 2002 Jan;24(1):37-61; quiz 74-6. PMID: 12196887
Local radiation therapy for localized relapsed or refractory ovarian cancer patients with or without symptoms after chemotherapy.
Fujiwara K, Suzuki S, Yoden E, Ishikawa H, Imajo Y, Kohno I
Int J Gynecol Cancer 2002 May-Jun;12(3):250-6. doi: 10.1046/j.1525-1438.2002.01096.x. PMID: 12060445

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    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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