U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Acute Monoblastic and Monocytic Leukemia

MedGen UID:
1719565
•Concept ID:
C2861618
•
Neoplastic Process
Synonym: Relapsed Acute Monoblastic and Monocytic Leukemia

Definition

The reemergence of acute monoblastic and monocytic leukemia after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Acute Monoblastic and Monocytic Leukemia

Recent clinical studies

Etiology

Subtype-specific patterns of molecular mutations in acute myeloid leukemia.
Rose D, Haferlach T, Schnittger S, Perglerová K, Kern W, Haferlach C
Leukemia 2017 Jan;31(1):11-17. Epub 2016 Jun 10 doi: 10.1038/leu.2016.163. PMID: 27285584
CYP2B6 gene single nucleotide polymorphisms and leukemia susceptibility.
Yuan ZH, Liu Q, Zhang Y, Liu HX, Zhao J, Zhu P
Ann Hematol 2011 Mar;90(3):293-9. Epub 2010 Sep 28 doi: 10.1007/s00277-010-1085-z. PMID: 20878158
Acute monoblastic leukemia: a unique subtype--a review from the Childrens Cancer Study Group.
Odom LF, Lampkin BC, Tannous R, Buckley JD, Hammond GD
Leuk Res 1990;14(1):1-10. doi: 10.1016/0145-2126(90)90140-5. PMID: 2406511
TdT+/nonlymphoid antigen+ acute leukemias: immunologic and karyotypic monitoring during therapy and at relapse suggests the transformation of a bipotential stem cell.
Paietta E, Gucalp R, Papenhausen P, Dutcher JP, Wiernik PH
Leukemia 1989 Jul;3(7):485-91. PMID: 2733453
Therapy of acute monoblastic leukemia.
Weil M, Jacquillat C, Tobelem G
Haematol Blood Transfus 1981;27:189-194. doi: 10.1007/978-3-642-81696-3_21. PMID: 6948758

Diagnosis

Acute myeloid leukemia with t(10;11): a pathological entity with distinct clinical presentation.
DiNardo CD, Tang G, Pemmaraju N, Wang SA, Pike A, Garcia-Manero G, Cortes J, Bueso-Ramos C, Kantarjian HM
Clin Lymphoma Myeloma Leuk 2015 Jan;15(1):47-51. Epub 2014 Jun 21 doi: 10.1016/j.clml.2014.06.022. PMID: 25081372Free PMC Article
Cardiac tamponade as the initial manifestation of acute leukemia: report of a case and review of the literature.
Batlle M, Ribera JM, Larrousse E, Abella E, Las Heras G, Milla F, Junca J
Haematologica 1991 Nov-Dec;76(6):505-7. PMID: 1820988
Acute monoblastic leukemia: a unique subtype--a review from the Childrens Cancer Study Group.
Odom LF, Lampkin BC, Tannous R, Buckley JD, Hammond GD
Leuk Res 1990;14(1):1-10. doi: 10.1016/0145-2126(90)90140-5. PMID: 2406511
Leukemia cutis treated with total skin irradiation.
Rubin CM, Arthur DC, Meyers G, McClain KL, Kim TH, Woods WG
Cancer 1985 Jun 1;55(11):2649-52. doi: 10.1002/1097-0142(19850601)55:11<2649::aid-cncr2820551120>3.0.co;2-x. PMID: 3888368

Therapy

Acute myeloid leukemia with t(10;11): a pathological entity with distinct clinical presentation.
DiNardo CD, Tang G, Pemmaraju N, Wang SA, Pike A, Garcia-Manero G, Cortes J, Bueso-Ramos C, Kantarjian HM
Clin Lymphoma Myeloma Leuk 2015 Jan;15(1):47-51. Epub 2014 Jun 21 doi: 10.1016/j.clml.2014.06.022. PMID: 25081372Free PMC Article
Cutaneous monoblastic leukemia as a first sign of relapse six years after autologous bone marrow transplantation for acute leukemia.
Weide R, Wacker HH, Köppler H, Görg C, Pflüger KH, Havemann K
Leuk Lymphoma 1996 Aug;22(5-6):527-9. doi: 10.3109/10428199609054794. PMID: 8882969
Cardiac tamponade as the initial manifestation of acute leukemia: report of a case and review of the literature.
Batlle M, Ribera JM, Larrousse E, Abella E, Las Heras G, Milla F, Junca J
Haematologica 1991 Nov-Dec;76(6):505-7. PMID: 1820988
Acute monoblastic leukemia: a unique subtype--a review from the Childrens Cancer Study Group.
Odom LF, Lampkin BC, Tannous R, Buckley JD, Hammond GD
Leuk Res 1990;14(1):1-10. doi: 10.1016/0145-2126(90)90140-5. PMID: 2406511
Therapy of acute monoblastic leukemia.
Weil M, Jacquillat C, Tobelem G
Haematol Blood Transfus 1981;27:189-194. doi: 10.1007/978-3-642-81696-3_21. PMID: 6948758

Prognosis

Clonal dynamics in a case of acute monoblastic leukemia that later developed myeloproliferative neoplasm.
Sato S, Itonaga H, Taguchi M, Sawayama Y, Imanishi D, Tsushima H, Hata T, Moriuchi Y, Mishima H, Kinoshita A, Yoshiura KI, Miyazaki Y
Int J Hematol 2018 Aug;108(2):213-217. Epub 2018 Feb 7 doi: 10.1007/s12185-018-2419-1. PMID: 29417354
Lineage switch with t(6;11)(q27;q23) from T-cell lymphoblastic lymphoma to acute monoblastic leukemia at relapse.
Higuchi Y, Tokunaga K, Watanabe Y, Kawakita T, Harada N, Yamaguchi S, Nosaka K, Mitsuya H, Asou N
Cancer Genet 2016 Jun;209(6):267-71. Epub 2016 May 18 doi: 10.1016/j.cancergen.2016.05.070. PMID: 27268298
Cutaneous monoblastic leukemia as a first sign of relapse six years after autologous bone marrow transplantation for acute leukemia.
Weide R, Wacker HH, Köppler H, Görg C, Pflüger KH, Havemann K
Leuk Lymphoma 1996 Aug;22(5-6):527-9. doi: 10.3109/10428199609054794. PMID: 8882969
Acute monoblastic leukemia: a unique subtype--a review from the Childrens Cancer Study Group.
Odom LF, Lampkin BC, Tannous R, Buckley JD, Hammond GD
Leuk Res 1990;14(1):1-10. doi: 10.1016/0145-2126(90)90140-5. PMID: 2406511
TdT+/nonlymphoid antigen+ acute leukemias: immunologic and karyotypic monitoring during therapy and at relapse suggests the transformation of a bipotential stem cell.
Paietta E, Gucalp R, Papenhausen P, Dutcher JP, Wiernik PH
Leukemia 1989 Jul;3(7):485-91. PMID: 2733453

Clinical prediction guides

Clonal dynamics in a case of acute monoblastic leukemia that later developed myeloproliferative neoplasm.
Sato S, Itonaga H, Taguchi M, Sawayama Y, Imanishi D, Tsushima H, Hata T, Moriuchi Y, Mishima H, Kinoshita A, Yoshiura KI, Miyazaki Y
Int J Hematol 2018 Aug;108(2):213-217. Epub 2018 Feb 7 doi: 10.1007/s12185-018-2419-1. PMID: 29417354
Gain of an isochromosome 5p: a new recurrent chromosome abnormality in acute monoblastic leukemia.
Schoch C, Bursch S, Kern W, Schnittger S, Hiddemann W, Haferlach T
Cancer Genet Cytogenet 2001 May;127(1):85-8. doi: 10.1016/s0165-4608(00)00424-6. PMID: 11408074
Cardiac tamponade as the initial manifestation of acute leukemia: report of a case and review of the literature.
Batlle M, Ribera JM, Larrousse E, Abella E, Las Heras G, Milla F, Junca J
Haematologica 1991 Nov-Dec;76(6):505-7. PMID: 1820988
TdT+/nonlymphoid antigen+ acute leukemias: immunologic and karyotypic monitoring during therapy and at relapse suggests the transformation of a bipotential stem cell.
Paietta E, Gucalp R, Papenhausen P, Dutcher JP, Wiernik PH
Leukemia 1989 Jul;3(7):485-91. PMID: 2733453

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...