U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Locally Advanced Biliary Tract Carcinoma

MedGen UID:
1719433
Concept ID:
C5239287
Neoplastic Process

Definition

Carcinoma that arises from the intrahepatic, hilar, extrahepatic bile ducts, cystic duct, or gallbladder and has spread to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Roth GS, Verlingue L, Sarabi M, Blanc JF, Boleslawski E, Boudjema K, Bretagne-Bignon AL, Camus-Duboc M, Coriat R, Créhange G, De Baere T, de la Fouchardière C, Dromain C, Edeline J, Gelli M, Guiu B, Horn S, Laurent-Croise V, Lepage C, Lièvre A, Lopez A, Manfredi S, Meilleroux J, Neuzillet C, Paradis V, Prat F, Ronot M, Rosmorduc O, Cunha AS, Soubrane O, Turpin A, Louvet C, Bouché O, Malka D
Eur J Cancer 2024 May;202:114000. Epub 2024 Mar 13 doi: 10.1016/j.ejca.2024.114000. PMID: 38493667
Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Masood A, Moravek C, Nakakura EK, Narang AK, Nardo L, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Truty MJ, Vollmer C, Wolff RA, Wolpin BM, Rn BM, Lubin S, Darlow SD
J Natl Compr Canc Netw 2023 Jul;21(7):753-782. doi: 10.6004/jnccn.2023.0034. PMID: 37433437
Moris D, Palta M, Kim C, Allen PJ, Morse MA, Lidsky ME
CA Cancer J Clin 2023 Mar;73(2):198-222. Epub 2022 Oct 19 doi: 10.3322/caac.21759. PMID: 36260350

Recent clinical studies

Etiology

Huang G, Song W, Zhang Y, Yu J, Lv Y, Liu K
Sci Rep 2023 Jun 30;13(1):10630. doi: 10.1038/s41598-023-37896-2. PMID: 37391482Free PMC Article
Soares KC, Jolissaint JS, McIntyre SM, Seier KP, Gönen M, Sigel C, Nasar N, Cercek A, Harding JJ, Kemeny NE, Connell LC, Koerkamp BG, Balachandran VP, D'Angelica MI, Drebin JA, Kingham TP, Wei AC, Jarnagin WR
Cancer Med 2023 Jun;12(11):12272-12284. Epub 2023 Apr 16 doi: 10.1002/cam4.5925. PMID: 37062071Free PMC Article
Lamarca A, Palmer DH, Wasan HS, Ross PJ, Ma YT, Arora A, Falk S, Gillmore R, Wadsley J, Patel K, Anthoney A, Maraveyas A, Iveson T, Waters JS, Hobbs C, Barber S, Ryder WD, Ramage J, Davies LM, Bridgewater JA, Valle JW; Advanced Biliary Cancer Working Group
Lancet Oncol 2021 May;22(5):690-701. Epub 2021 Mar 30 doi: 10.1016/S1470-2045(21)00027-9. PMID: 33798493Free PMC Article
Ashai N, Prasad P, Rajdev L
Curr Treat Options Oncol 2019 May 29;20(7):58. doi: 10.1007/s11864-019-0655-0. PMID: 31144050
Jonas S, Benckert C, Thelen A, Lopez-Hänninen E, Rösch T, Neuhaus P
Eur J Surg Oncol 2008 Mar;34(3):263-71. Epub 2007 Nov 26 doi: 10.1016/j.ejso.2007.09.024. PMID: 18042497

Diagnosis

Dai YS, Gao W, Hu HJ, Jin YW, Li FY
Ann Surg Oncol 2024 May;31(5):3059-3061. Epub 2024 Jan 27 doi: 10.1245/s10434-024-14905-w. PMID: 38280962
Dhote A, Tzedakis S, Shapira OI, Nassar A, Boudjema K, Fuks D
J Visc Surg 2023 Oct;160(5):346-355. Epub 2023 Aug 8 doi: 10.1016/j.jviscsurg.2023.07.007. PMID: 37563006
Lamarca A, Edeline J, Goyal L
ESMO Open 2022 Feb;7(1):100378. Epub 2022 Jan 13 doi: 10.1016/j.esmoop.2021.100378. PMID: 35032765Free PMC Article
Uson Junior PLS, Borad MJ
Expert Opin Investig Drugs 2022 Jan;31(1):125-131. Epub 2022 Jan 7 doi: 10.1080/13543784.2022.2017882. PMID: 34904492
Hashimoto K, Miller CM
J Hepatobiliary Pancreat Sci 2015 Feb;22(2):138-43. Epub 2014 Sep 12 doi: 10.1002/jhbp.159. PMID: 25214036

Therapy

Meric-Bernstam F, Makker V, Oaknin A, Oh DY, Banerjee S, González-Martín A, Jung KH, Ługowska I, Manso L, Manzano A, Melichar B, Siena S, Stroyakovskiy D, Fielding A, Ma Y, Puvvada S, Shire N, Lee JY
J Clin Oncol 2024 Jan 1;42(1):47-58. Epub 2023 Oct 23 doi: 10.1200/JCO.23.02005. PMID: 37870536Free PMC Article
Moris D, Palta M, Kim C, Allen PJ, Morse MA, Lidsky ME
CA Cancer J Clin 2023 Mar;73(2):198-222. Epub 2022 Oct 19 doi: 10.3322/caac.21759. PMID: 36260350
Sadeghi S
Drugs Today (Barc) 2022 Jul;58(7):327-334. doi: 10.1358/dot.2022.58.7.3408813. PMID: 35851868
Ashai N, Prasad P, Rajdev L
Curr Treat Options Oncol 2019 May 29;20(7):58. doi: 10.1007/s11864-019-0655-0. PMID: 31144050
Kuhlmann JB, Blum HE
Curr Opin Gastroenterol 2013 May;29(3):324-8. doi: 10.1097/MOG.0b013e32835d9dea. PMID: 23337933

Prognosis

Kodali S, Connor AA, Thabet S, Brombosz EW, Ghobrial RM
Hepatobiliary Pancreat Dis Int 2024 Apr;23(2):129-138. Epub 2023 Jul 23 doi: 10.1016/j.hbpd.2023.07.007. PMID: 37517983
Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Masood A, Moravek C, Nakakura EK, Narang AK, Nardo L, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Truty MJ, Vollmer C, Wolff RA, Wolpin BM, Rn BM, Lubin S, Darlow SD
J Natl Compr Canc Netw 2023 Jul;21(7):753-782. doi: 10.6004/jnccn.2023.0034. PMID: 37433437
Gupta P, Marodia Y, Bansal A, Kalra N, Kumar-M P, Sharma V, Dutta U, Sandhu MS
World J Gastroenterol 2020 Oct 28;26(40):6163-6181. doi: 10.3748/wjg.v26.i40.6163. PMID: 33177791Free PMC Article
Hashimoto K, Miller CM
J Hepatobiliary Pancreat Sci 2015 Feb;22(2):138-43. Epub 2014 Sep 12 doi: 10.1002/jhbp.159. PMID: 25214036
Kuhlmann JB, Blum HE
Curr Opin Gastroenterol 2013 May;29(3):324-8. doi: 10.1097/MOG.0b013e32835d9dea. PMID: 23337933

Clinical prediction guides

Meric-Bernstam F, Makker V, Oaknin A, Oh DY, Banerjee S, González-Martín A, Jung KH, Ługowska I, Manso L, Manzano A, Melichar B, Siena S, Stroyakovskiy D, Fielding A, Ma Y, Puvvada S, Shire N, Lee JY
J Clin Oncol 2024 Jan 1;42(1):47-58. Epub 2023 Oct 23 doi: 10.1200/JCO.23.02005. PMID: 37870536Free PMC Article
Kodali S, Connor AA, Thabet S, Brombosz EW, Ghobrial RM
Hepatobiliary Pancreat Dis Int 2024 Apr;23(2):129-138. Epub 2023 Jul 23 doi: 10.1016/j.hbpd.2023.07.007. PMID: 37517983
Soares KC, Jolissaint JS, McIntyre SM, Seier KP, Gönen M, Sigel C, Nasar N, Cercek A, Harding JJ, Kemeny NE, Connell LC, Koerkamp BG, Balachandran VP, D'Angelica MI, Drebin JA, Kingham TP, Wei AC, Jarnagin WR
Cancer Med 2023 Jun;12(11):12272-12284. Epub 2023 Apr 16 doi: 10.1002/cam4.5925. PMID: 37062071Free PMC Article
Gupta P, Marodia Y, Bansal A, Kalra N, Kumar-M P, Sharma V, Dutta U, Sandhu MS
World J Gastroenterol 2020 Oct 28;26(40):6163-6181. doi: 10.3748/wjg.v26.i40.6163. PMID: 33177791Free PMC Article
Mohr R, Özdirik B, Knorr J, Wree A, Demir M, Tacke F, Roderburg C
Int J Mol Sci 2020 Jul 15;21(14) doi: 10.3390/ijms21144993. PMID: 32679791Free PMC Article

Recent systematic reviews

Ziogas IA, Rallis KS, Tasoudis PT, Moris D, Schulick RD, Del Chiaro M
Eur J Surg Oncol 2023 Apr;49(4):682-687. Epub 2023 Jan 9 doi: 10.1016/j.ejso.2023.01.005. PMID: 36646615
Abdel-Rahman O, Elsayed Z, Elhalawani H
Cochrane Database Syst Rev 2018 Apr 6;4(4):CD011746. doi: 10.1002/14651858.CD011746.pub2. PMID: 29624208Free PMC Article
Dhir M, Malhotra GK, Sohal DPS, Hein NA, Smith LM, O'Reilly EM, Bahary N, Are C
World J Surg Oncol 2017 Oct 10;15(1):183. doi: 10.1186/s12957-017-1240-2. PMID: 29017581Free PMC Article
Al-Adra DP, Gill RS, Axford SJ, Shi X, Kneteman N, Liau SS
Eur J Surg Oncol 2015 Jan;41(1):120-7. Epub 2014 Oct 7 doi: 10.1016/j.ejso.2014.09.007. PMID: 25449754Free PMC Article
Grendar J, Grendarova P, Sinha R, Dixon E
HPB (Oxford) 2014 Apr;16(4):297-303. Epub 2013 Aug 26 doi: 10.1111/hpb.12150. PMID: 23981000Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...