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Refractory Acute Graft Versus Host Disease

MedGen UID:
1718903
Concept ID:
C5237289
Disease or Syndrome

Definition

Acute graft versus host disease that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Acute Graft Versus Host Disease

Professional guidelines

PubMed

Cazeau N, Rodriguez SL
Clin J Oncol Nurs 2023 Jul 20;27(4):397-403. doi: 10.1188/23.CJON.397-403. PMID: 37677777
Murata M, Teshima T
Front Immunol 2021;12:724380. Epub 2021 Aug 19 doi: 10.3389/fimmu.2021.724380. PMID: 34489977Free PMC Article
Malard F, Huang XJ, Sim JPY
Leukemia 2020 May;34(5):1229-1240. Epub 2020 Apr 3 doi: 10.1038/s41375-020-0804-2. PMID: 32242050Free PMC Article

Recent clinical studies

Etiology

Liu J, Fan Z, Xu N, Ye J, Chen Y, Shao R, Sun Y, Wu Q, Liu Q, Jin H
Ann Hematol 2023 Oct;102(10):2865-2877. Epub 2023 Jul 20 doi: 10.1007/s00277-023-05361-9. PMID: 37474631
Mo XD, Hong SD, Zhao YL, Jiang EL, Chen J, Xu Y, Sun ZM, Zhang WJ, Liu QF, Liu DH, Wan DM, Mo WJ, Ren HY, Yang T, Huang H, Zhang X, Wang XN, Song XM, Gao SJ, Wang X, Chen Y, Xu B, Jiang M, Huang XB, Li X, Zhang HY, Wang HT, Wang Z, Niu T, Wang JS, Xia LH, Liu XD, Li F, Zhou F, Lang T, Hu J, Wu SJ, Huang XJ
Am J Hematol 2022 Apr;97(4):458-469. Epub 2022 Feb 4 doi: 10.1002/ajh.26475. PMID: 35064928
Hill GR, Koyama M
Blood 2020 Jul 23;136(4):418-428. doi: 10.1182/blood.2019000952. PMID: 32526028Free PMC Article
Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R, Szer J, Wagner EM, Zuckerman T, Mahuzier B, Xu J, Wilke C, Gandhi KK, Socié G; REACH2 Trial Group
N Engl J Med 2020 May 7;382(19):1800-1810. Epub 2020 Apr 22 doi: 10.1056/NEJMoa1917635. PMID: 32320566
Escamilla Gómez V, García-Gutiérrez V, López Corral L, García Cadenas I, Pérez Martínez A, Márquez Malaver FJ, Caballero-Velázquez T, González Sierra PA, Viguria Alegría MC, Parra Salinas IM, Calderón Cabrera C, González Vicent M, Rodríguez Torres N, Parody Porras R, Ferra Coll C, Orti G, Valcárcel Ferreiras D, De la Cámara LLanzá R, Molés P, Velázquez-Kennedy K, João Mende M, Caballero Barrigón D, Pérez E, Martino Bofarull R, Saavedra Gerosa S, Sierra J, Poch M, Zudaire Ripa MT, Díaz Pérez MA, Molina Angulo B, Sánchez Ortega I, Sanz Caballer J, Montoro Gómez J, Espigado Tocino I, Pérez-Simón JA; Grupo Español de Trasplante Hematopoyético (GETH)
Bone Marrow Transplant 2020 Mar;55(3):641-648. Epub 2019 Nov 7 doi: 10.1038/s41409-019-0731-x. PMID: 31700138Free PMC Article

Diagnosis

Cook E, Dong M, Chiang SCC, Luedeke D, Lake KE, Hoerth C, Deavy M, Setchell KDR, Zhao J, Punt N, Galletta T, Teusink-Cross A, Davies SM, Marsh RA, Mehta P, Khandelwal P
Transplant Cell Ther 2024 May;30(5):528.e1-528.e12. Epub 2024 Feb 22 doi: 10.1016/j.jtct.2024.02.018. PMID: 38401793
Leeneman B, Blommestein HM, van Dongen-Leunis A, Algeri M, Fibbe WE, Oosten L, Uyl-de Groot CA, Thielen FW
Eur J Haematol 2023 Aug;111(2):240-246. Epub 2023 May 3 doi: 10.1111/ejh.13987. PMID: 37137484
Verbeek AB, Jansen SA, von Asmuth EGJ, Lankester AC, Bresters D, Bierings M, Mohseny AB, Lindemans CA, Buddingh EP
Transplant Cell Ther 2022 Sep;28(9):600.e1-600.e9. Epub 2022 Jun 16 doi: 10.1016/j.jtct.2022.06.008. PMID: 35717003
Rashidi A, DeFor TE, Holtan SG, Blazar BR, Weisdorf DJ, MacMillan ML
Biol Blood Marrow Transplant 2019 Nov;25(11):2297-2302. Epub 2019 Jul 17 doi: 10.1016/j.bbmt.2019.07.017. PMID: 31325587Free PMC Article
Roddy JV, Haverkos BM, McBride A, Leininger KM, Jaglowski S, Penza S, Klisovic R, Blum W, Vasu S, Hofmeister CC, Benson DM, Andritsos LA, Devine SM, Efebera YA
Leuk Lymphoma 2016;57(1):81-5. Epub 2015 Jul 3 doi: 10.3109/10428194.2015.1045896. PMID: 26140610Free PMC Article

Therapy

Cazeau N, Rodriguez SL
Clin J Oncol Nurs 2023 Jul 20;27(4):397-403. doi: 10.1188/23.CJON.397-403. PMID: 37677777
Liu J, Fan Z, Xu N, Ye J, Chen Y, Shao R, Sun Y, Wu Q, Liu Q, Jin H
Ann Hematol 2023 Oct;102(10):2865-2877. Epub 2023 Jul 20 doi: 10.1007/s00277-023-05361-9. PMID: 37474631
Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R, Szer J, Wagner EM, Zuckerman T, Mahuzier B, Xu J, Wilke C, Gandhi KK, Socié G; REACH2 Trial Group
N Engl J Med 2020 May 7;382(19):1800-1810. Epub 2020 Apr 22 doi: 10.1056/NEJMoa1917635. PMID: 32320566
Malard F, Huang XJ, Sim JPY
Leukemia 2020 May;34(5):1229-1240. Epub 2020 Apr 3 doi: 10.1038/s41375-020-0804-2. PMID: 32242050Free PMC Article
Jagasia M, Perales MA, Schroeder MA, Ali H, Shah NN, Chen YB, Fazal S, Dawkins FW, Arbushites MC, Tian C, Connelly-Smith L, Howell MD, Khoury HJ
Blood 2020 May 14;135(20):1739-1749. doi: 10.1182/blood.2020004823. PMID: 32160294Free PMC Article

Prognosis

Mo XD, Hong SD, Zhao YL, Jiang EL, Chen J, Xu Y, Sun ZM, Zhang WJ, Liu QF, Liu DH, Wan DM, Mo WJ, Ren HY, Yang T, Huang H, Zhang X, Wang XN, Song XM, Gao SJ, Wang X, Chen Y, Xu B, Jiang M, Huang XB, Li X, Zhang HY, Wang HT, Wang Z, Niu T, Wang JS, Xia LH, Liu XD, Li F, Zhou F, Lang T, Hu J, Wu SJ, Huang XJ
Am J Hematol 2022 Apr;97(4):458-469. Epub 2022 Feb 4 doi: 10.1002/ajh.26475. PMID: 35064928
Murata M, Teshima T
Front Immunol 2021;12:724380. Epub 2021 Aug 19 doi: 10.3389/fimmu.2021.724380. PMID: 34489977Free PMC Article
Jagasia M, Perales MA, Schroeder MA, Ali H, Shah NN, Chen YB, Fazal S, Dawkins FW, Arbushites MC, Tian C, Connelly-Smith L, Howell MD, Khoury HJ
Blood 2020 May 14;135(20):1739-1749. doi: 10.1182/blood.2020004823. PMID: 32160294Free PMC Article
Rashidi A, DeFor TE, Holtan SG, Blazar BR, Weisdorf DJ, MacMillan ML
Biol Blood Marrow Transplant 2019 Nov;25(11):2297-2302. Epub 2019 Jul 17 doi: 10.1016/j.bbmt.2019.07.017. PMID: 31325587Free PMC Article
Hashmi S, Ahmed M, Murad MH, Litzow MR, Adams RH, Ball LM, Prasad VK, Kebriaei P, Ringden O
Lancet Haematol 2016 Jan;3(1):e45-52. Epub 2015 Nov 27 doi: 10.1016/S2352-3026(15)00224-0. PMID: 26765648

Clinical prediction guides

Lafarge A, Dupont T, Canet E, Moreau AS, Picard M, Mokart D, Platon L, Mayaux J, Wallet F, Issa N, Raphalen JH, Pène F, Renault A, Peffault de la Tour R, Récher C, Chevallier P, Zafrani L, Darmon M, Bigé N, Azoulay E
Am J Respir Crit Care Med 2024 Oct 15;210(8):1017-1024. doi: 10.1164/rccm.202401-0135OC. PMID: 39018219
Mo XD, Hong SD, Zhao YL, Jiang EL, Chen J, Xu Y, Sun ZM, Zhang WJ, Liu QF, Liu DH, Wan DM, Mo WJ, Ren HY, Yang T, Huang H, Zhang X, Wang XN, Song XM, Gao SJ, Wang X, Chen Y, Xu B, Jiang M, Huang XB, Li X, Zhang HY, Wang HT, Wang Z, Niu T, Wang JS, Xia LH, Liu XD, Li F, Zhou F, Lang T, Hu J, Wu SJ, Huang XJ
Am J Hematol 2022 Apr;97(4):458-469. Epub 2022 Feb 4 doi: 10.1002/ajh.26475. PMID: 35064928
Murata M, Teshima T
Front Immunol 2021;12:724380. Epub 2021 Aug 19 doi: 10.3389/fimmu.2021.724380. PMID: 34489977Free PMC Article
Zeiser R, von Bubnoff N, Butler J, Mohty M, Niederwieser D, Or R, Szer J, Wagner EM, Zuckerman T, Mahuzier B, Xu J, Wilke C, Gandhi KK, Socié G; REACH2 Trial Group
N Engl J Med 2020 May 7;382(19):1800-1810. Epub 2020 Apr 22 doi: 10.1056/NEJMoa1917635. PMID: 32320566
Jagasia M, Perales MA, Schroeder MA, Ali H, Shah NN, Chen YB, Fazal S, Dawkins FW, Arbushites MC, Tian C, Connelly-Smith L, Howell MD, Khoury HJ
Blood 2020 May 14;135(20):1739-1749. doi: 10.1182/blood.2020004823. PMID: 32160294Free PMC Article

Recent systematic reviews

Shen MZ, Li JX, Zhang XH, Xu LP, Wang Y, Liu KY, Huang XJ, Hong SD, Mo XD
Front Immunol 2021;12:749266. Epub 2021 Sep 21 doi: 10.3389/fimmu.2021.749266. PMID: 34621279Free PMC Article
Hashmi S, Ahmed M, Murad MH, Litzow MR, Adams RH, Ball LM, Prasad VK, Kebriaei P, Ringden O
Lancet Haematol 2016 Jan;3(1):e45-52. Epub 2015 Nov 27 doi: 10.1016/S2352-3026(15)00224-0. PMID: 26765648
Chen X, Wang C, Yin J, Xu J, Wei J, Zhang Y
PLoS One 2015;10(8):e0136991. Epub 2015 Aug 31 doi: 10.1371/journal.pone.0136991. PMID: 26323092Free PMC Article

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