U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cutaneous Indeterminate Dendritic Cell Histiocytosis

MedGen UID:
1709305
•Concept ID:
C5239288
•
Neoplastic Process
Synonyms: Cutaneous Indeterminate Cell Histiocytosis; Cutaneous Indeterminate Dendritic Cell Tumor

Definition

A very rare dendritic cell tumor affecting the skin. It is composed of spindle to ovoid cells with a phenotype that is similar to the Langerhans cells. It manifests with cutaneous papules, nodules, and plaques. The clinical course is variable. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous Indeterminate Dendritic Cell Histiocytosis

Recent clinical studies

Therapy

Indeterminate cell histiocytosis in a patient with systemic lupus erythematosus and antiphospholipid antibody syndrome: an unusual association.
Akdogan N, Demircan C, Bolek EC, Gokoz O, Karaduman A
Lupus 2020 Jan;29(1):74-78. Epub 2019 Dec 1 doi: 10.1177/0961203319890675. PMID: 31789127
Cutaneous Indeterminate Cell Histiocytosis of Donor Origin After Allogeneic Hematopoietic Stem-Cell Transplantation.
Santos-Briz A, Román C, Corral R, de Dios A, Vázquez L, Ludeña MD
Am J Dermatopathol 2017 Sep;39(9):696-699. doi: 10.1097/DAD.0000000000000935. PMID: 28825606

Prognosis

Indeterminate Dendritic Cell Tumor: A Report of Two New Cases Lacking the ETV3-NCOA2 Translocation and a Literature Review.
Davick JJ, Kim J, Wick MR, Gru AA
Am J Dermatopathol 2018 Oct;40(10):736-748. doi: 10.1097/DAD.0000000000001191. PMID: 29877893

Clinical prediction guides

Indeterminate Dendritic Cell Tumor: A Report of Two New Cases Lacking the ETV3-NCOA2 Translocation and a Literature Review.
Davick JJ, Kim J, Wick MR, Gru AA
Am J Dermatopathol 2018 Oct;40(10):736-748. doi: 10.1097/DAD.0000000000001191. PMID: 29877893
Self-regressing S100-negative CD1a-positive cutaneous histiocytosis.
Tardío JC, Aguado M, Borbujo J
Am J Dermatopathol 2013 Jun;35(4):e57-9. doi: 10.1097/DAD.0b013e31827adc72. PMID: 23334517
Indeterminate cell histiocytosis. Clinical and pathologic study in a pediatric patient.
Rodríguez-Jurado R, Vidaurri-de la Cruz H, Durán-Mckinster C, Ruíz-Maldonado R
Arch Pathol Lab Med 2003 Jun;127(6):748-51. doi: 10.5858/2003-127-748-ICH. PMID: 12741905

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...