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Increased circulating IgG4 level

MedGen UID:
1707521
Concept ID:
C5139257
Finding
HPO: HP:0032300

Definition

An abnormally increased concentration of the IgG4 subtype in the blood circulation. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Sloan EE, Kmetova K, NaveenKumar SK, Kluge L, Chong E, Hoy CK, Yalavarthi S, Sarosh C, Baisch J, Walters L, Nassi L, Fuller J, Turnier JL, Pascual V, Wright TB, Madison JA, Knight JS, Zia A, Zuo Y
Clin Immunol 2024 Apr;261:109926. Epub 2024 Feb 13 doi: 10.1016/j.clim.2024.109926. PMID: 38355030Free PMC Article
Fedele G, Schiavoni I, Trentini F, Leone P, Olivetta E, Fallucca A, Fiore S, Di Martino A, Abrignani S, Baldo V, Baldovin T, Bandera A, Clerici P, De Paschale M, Diaco F, Domnich A, Fortunato F, Giberti I, Gori A, Grifantini R, Lazzarotto T, Lodi V, Mastroianni CM, Prato R, Restivo V, Vitale F, Brusaferro S, Merler S, Palamara AT, Stefanelli P; Study Group for the Immunological Monitoring post Covid19 vaccination
Front Immunol 2023;14:1272119. Epub 2023 Nov 20 doi: 10.3389/fimmu.2023.1272119. PMID: 38077369Free PMC Article
Handler MZ, Schwartz RA
J Eur Acad Dermatol Venereol 2014 Nov;28(11):1418-23. Epub 2014 May 20 doi: 10.1111/jdv.12541. PMID: 24841497

Recent clinical studies

Etiology

Bradford HF, Haljasmägi L, Menon M, McDonnell TCR, Särekannu K, Vanker M, Peterson P, Wincup C, Abida R, Gonzalez RF, Bondet V, Duffy D, Isenberg DA, Kisand K, Mauri C
Cell Rep Med 2023 Jan 17;4(1):100894. doi: 10.1016/j.xcrm.2022.100894. PMID: 36652906Free PMC Article
Bertin D, Brodovitch A, Lopez A, Arcani R, Thomas GM, Beziane A, Weber S, Babacci B, Heim X, Rey L, Leone M, Mege JL, Bardin N
Sci Rep 2022 Jul 22;12(1):12523. doi: 10.1038/s41598-022-15969-y. PMID: 35869087Free PMC Article
Tao J, Song D, Liu XL, Yu F, Zhao MH
Clin Immunol 2020 Aug;217:108514. Epub 2020 Jun 18 doi: 10.1016/j.clim.2020.108514. PMID: 32565324
Kennerknecht N, Riffelmann M, Voelker U, Wirsing von König CH
Epidemiol Infect 2018 Oct;146(14):1807-1810. Epub 2018 Jul 10 doi: 10.1017/S0950268818001851. PMID: 29986784Free PMC Article
Brettler DB
Baillieres Clin Haematol 1996 Jun;9(2):319-29. doi: 10.1016/s0950-3536(96)80066-7. PMID: 8800508

Diagnosis

Aranda CJ, Gonzalez-Kozlova E, Saunders SP, Fernandes-Braga W, Ota M, Narayanan S, He JS, Del Duca E, Swaroop B, Gnjatic S, Shattner G, Reibman J, Soter NA, Guttman-Yassky E, Curotto de Lafaille MA
Allergy 2023 Mar;78(3):752-766. Epub 2022 Dec 19 doi: 10.1111/all.15601. PMID: 36445014Free PMC Article
Krátká Z, Fejt V, Kučera R, Fürst T, Zelená H
Cas Lek Cesk 2021 Fall;160(5):167-175. PMID: 34674530
Okada S, Hasegawa S, Suzuki Y, Ichimura T, Kaneyasu H, Shimomura M, Wakabayashi-Takahara M, Nakamura K, Kobayashi M, Ohga S
Pediatr Int 2015 Oct;57(5):1012-4. Epub 2015 Sep 10 doi: 10.1111/ped.12701. PMID: 26508185
Handler MZ, Schwartz RA
J Eur Acad Dermatol Venereol 2014 Nov;28(11):1418-23. Epub 2014 May 20 doi: 10.1111/jdv.12541. PMID: 24841497
Berlacher MD, Vieth JA, Heflin BC, Gay SR, Antczak AJ, Tasma BE, Boardman HJ, Singh N, Montel AH, Kahaleh MB, Worth RG
Am J Pathol 2013 Jan;182(1):244-54. Epub 2012 Nov 7 doi: 10.1016/j.ajpath.2012.09.005. PMID: 23141924

Therapy

Neuhann JM, Stemler J, Carcas AJ, Frías-Iniesta J, Akova M, Bethe U, Heringer S, Salmanton-García J, Tischmann L, Zarrouk M, Cüppers A, Grothe J, Leon AG, Mallon P, Negi R, Gaillard C, Saini G, Lammens C, Hotterbeekx A, Loens K, Malhotra-Kumar S, Goossens H, Kumar-Singh S, König F, Yeghiazaryan L, Posch M, Koehler P, Cornely OA
Vaccine 2023 Nov 22;41(48):7166-7175. Epub 2023 Oct 31 doi: 10.1016/j.vaccine.2023.10.029. PMID: 37919141
Bradford HF, Haljasmägi L, Menon M, McDonnell TCR, Särekannu K, Vanker M, Peterson P, Wincup C, Abida R, Gonzalez RF, Bondet V, Duffy D, Isenberg DA, Kisand K, Mauri C
Cell Rep Med 2023 Jan 17;4(1):100894. doi: 10.1016/j.xcrm.2022.100894. PMID: 36652906Free PMC Article
Charlton CL, Lai FY, Dover DC
Hum Vaccin Immunother 2016 Apr 2;12(4):903-6. doi: 10.1080/21645515.2015.1128600. PMID: 26811063Free PMC Article
Wang Y, Tian Z, Thirumalai D, Zhang X
J Drug Target 2014 May;22(4):269-78. Epub 2014 Jan 9 doi: 10.3109/1061186X.2013.875030. PMID: 24404896
Saegeman V, Wynendaele W, Kerre S, Dedeurwaerdere F, Van den Driessche M, Moerman J
Transfusion 2009 Feb;49(2):372-45. Epub 2008 Oct 28 doi: 10.1111/j.1537-2995.2008.01956.x. PMID: 18980620

Prognosis

Krátká Z, Fejt V, Kučera R, Fürst T, Zelená H
Cas Lek Cesk 2021 Fall;160(5):167-175. PMID: 34674530
Kennerknecht N, Riffelmann M, Voelker U, Wirsing von König CH
Epidemiol Infect 2018 Oct;146(14):1807-1810. Epub 2018 Jul 10 doi: 10.1017/S0950268818001851. PMID: 29986784Free PMC Article
Okada S, Hasegawa S, Suzuki Y, Ichimura T, Kaneyasu H, Shimomura M, Wakabayashi-Takahara M, Nakamura K, Kobayashi M, Ohga S
Pediatr Int 2015 Oct;57(5):1012-4. Epub 2015 Sep 10 doi: 10.1111/ped.12701. PMID: 26508185
Handler MZ, Schwartz RA
J Eur Acad Dermatol Venereol 2014 Nov;28(11):1418-23. Epub 2014 May 20 doi: 10.1111/jdv.12541. PMID: 24841497
Berthoux F, Suzuki H, Thibaudin L, Yanagawa H, Maillard N, Mariat C, Tomino Y, Julian BA, Novak J
J Am Soc Nephrol 2012 Sep;23(9):1579-87. Epub 2012 Aug 16 doi: 10.1681/ASN.2012010053. PMID: 22904352Free PMC Article

Clinical prediction guides

Turmukhambetova A, Yegorov S, Korshukov I, Barkhanskaya V, Kolesnichenko S, Klyuyev D, Zhumadilova Z, Pralieva A, Absaghit L, Belyaev R, Babenko D, Hortelano GH, Miller MS, Vazenmiller D, Kadyrova I
PLoS One 2023;18(10):e0293074. Epub 2023 Oct 18 doi: 10.1371/journal.pone.0293074. PMID: 37851684Free PMC Article
Bradford HF, Haljasmägi L, Menon M, McDonnell TCR, Särekannu K, Vanker M, Peterson P, Wincup C, Abida R, Gonzalez RF, Bondet V, Duffy D, Isenberg DA, Kisand K, Mauri C
Cell Rep Med 2023 Jan 17;4(1):100894. doi: 10.1016/j.xcrm.2022.100894. PMID: 36652906Free PMC Article
Vicente MM, Alves I, Gaifem J, Rodrigues CS, Fernandes Â, Dias AM, Štambuk J, Petrović T, Oliveira P, Ferreira-da-Silva F, Soares A, Seixas N, Teixeira T, Malheiro L, Abreu MM, Lauc G, Sarmento E Castro R, Pinho SS
Eur J Immunol 2022 Jun;52(6):946-957. Epub 2022 Apr 4 doi: 10.1002/eji.202149491. PMID: 35307819Free PMC Article
Borodina E, Katz I, Antonelli A, Gzgzyan AM, Dzhemlikhanova LK, Ostrinski Y, Niauri D, Khizroeva J, Bitsadze V, Makatsariya A, Tincani A, Nalli C, Churilov LP, Shovman O, Halpert G, Blank M, Shoenfeld Y, Amital H
Am J Reprod Immunol 2021 Jan;85(1):e13331. Epub 2020 Sep 20 doi: 10.1111/aji.13331. PMID: 32893404
Kennerknecht N, Riffelmann M, Voelker U, Wirsing von König CH
Epidemiol Infect 2018 Oct;146(14):1807-1810. Epub 2018 Jul 10 doi: 10.1017/S0950268818001851. PMID: 29986784Free PMC Article

Recent systematic reviews

Zhou Y, Shao L, Ruan W, Jin J, Xu H, Ying K, Wu X
Medicine (Baltimore) 2019 Feb;98(6):e14437. doi: 10.1097/MD.0000000000014437. PMID: 30732204Free PMC Article

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