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Metastatic Gastrointestinal Stromal Tumor

MedGen UID:
1659379
Concept ID:
C4725951
Neoplastic Process

Definition

Gastrointestinal stromal tumor which has spread from its original site of growth to another anatomic site. [from NCI]

Professional guidelines

PubMed

Liu H, Liao G, Yan Z
BMC Gastroenterol 2011 Nov 2;11:116. doi: 10.1186/1471-230X-11-116. PMID: 22047550Free PMC Article
Cirocchi R, Farinella E, La Mura F, Cavaliere D, Avenia N, Verdecchia GM, Giustozzi G, Noya G, Sciannameo F
Tumori 2010 May-Jun;96(3):392-9. doi: 10.1177/030089161009600303. PMID: 20845798
Gronchi A, Blay JY, Trent JC
Cancer 2010 Apr 15;116(8):1847-58. doi: 10.1002/cncr.24944. PMID: 20166214

Recent clinical studies

Etiology

Raghavan K, Flavell RR, Westphalen AC, Behr SC
Clin Nucl Med 2021 Apr 1;46(4):345-347. doi: 10.1097/RLU.0000000000003426. PMID: 33234933
Fu J, Fang MJ, Dong D, Li J, Sun YS, Tian J, Tang L
Eur J Radiol 2020 Apr;125:108825. Epub 2020 Jan 30 doi: 10.1016/j.ejrad.2020.108825. PMID: 32035324
Serrano C, García-Del-Muro X, Valverde C, Sebio A, Durán J, Manzano A, Pajares I, Hindi N, Landolfi S, Jiménez L, Rubió-Casadevall J, Estival A, Lavernia J, Safont MJ, Pericay C, Díaz-Beveridge R, Martínez-Marín V, Vicente-Baz D, Vivancos A, Hernández-Losa J, Arribas J, Carles J
Oncologist 2019 May;24(5):680-687. Epub 2018 Aug 20 doi: 10.1634/theoncologist.2018-0032. PMID: 30126859Free PMC Article
Pessetto ZY, Weir SJ, Sethi G, Broward MA, Godwin AK
Mol Cancer Ther 2013 Jul;12(7):1299-309. Epub 2013 May 8 doi: 10.1158/1535-7163.MCT-12-0968. PMID: 23657945Free PMC Article
Stauffer JA, Steers JL, Bonatti H, Dougherty MK, Aranda-Michel J, Dickson RC, Harnois DM, Nguyen JH
Liver Transpl 2009 Dec;15(12):1728-37. doi: 10.1002/lt.21932. PMID: 19938125

Diagnosis

Serrano C, Bauer S, Gómez-Peregrina D, Kang YK, Jones RL, Rutkowski P, Mir O, Heinrich MC, Tap WD, Newberry K, Grassian A, Shi H, Bialick S, Schöffski P, Pantaleo MA, von Mehren M, Trent JC, George S
Ann Oncol 2023 Jul;34(7):615-625. Epub 2023 Apr 25 doi: 10.1016/j.annonc.2023.04.006. PMID: 37105265Free PMC Article
Bharath BG, Rastogi S, Ahmed S, Barwad A
J Med Case Rep 2022 May 1;16(1):174. doi: 10.1186/s13256-022-03382-y. PMID: 35490251Free PMC Article
Hong AR, Yoon JH, Kim HK, Kang HC
Front Endocrinol (Lausanne) 2020;11:451. Epub 2020 Jul 14 doi: 10.3389/fendo.2020.00451. PMID: 32760348Free PMC Article
Serrano C, García-Del-Muro X, Valverde C, Sebio A, Durán J, Manzano A, Pajares I, Hindi N, Landolfi S, Jiménez L, Rubió-Casadevall J, Estival A, Lavernia J, Safont MJ, Pericay C, Díaz-Beveridge R, Martínez-Marín V, Vicente-Baz D, Vivancos A, Hernández-Losa J, Arribas J, Carles J
Oncologist 2019 May;24(5):680-687. Epub 2018 Aug 20 doi: 10.1634/theoncologist.2018-0032. PMID: 30126859Free PMC Article
Sandrasegaran K, Rajesh A, Rushing DA, Rydberg J, Akisik FM, Henley JD
Eur Radiol 2005 Jul;15(7):1407-14. Epub 2005 Mar 11 doi: 10.1007/s00330-005-2647-7. PMID: 15761716

Therapy

Gómez-Peregrina D, Cicala CM, Serrano C
Curr Opin Oncol 2024 Jul 1;36(4):282-290. Epub 2024 Apr 19 doi: 10.1097/CCO.0000000000001040. PMID: 38726808
Serrano C, Bauer S, Gómez-Peregrina D, Kang YK, Jones RL, Rutkowski P, Mir O, Heinrich MC, Tap WD, Newberry K, Grassian A, Shi H, Bialick S, Schöffski P, Pantaleo MA, von Mehren M, Trent JC, George S
Ann Oncol 2023 Jul;34(7):615-625. Epub 2023 Apr 25 doi: 10.1016/j.annonc.2023.04.006. PMID: 37105265Free PMC Article
Serrano C, García-Del-Muro X, Valverde C, Sebio A, Durán J, Manzano A, Pajares I, Hindi N, Landolfi S, Jiménez L, Rubió-Casadevall J, Estival A, Lavernia J, Safont MJ, Pericay C, Díaz-Beveridge R, Martínez-Marín V, Vicente-Baz D, Vivancos A, Hernández-Losa J, Arribas J, Carles J
Oncologist 2019 May;24(5):680-687. Epub 2018 Aug 20 doi: 10.1634/theoncologist.2018-0032. PMID: 30126859Free PMC Article
Dizdar O, Yalcin S
Hepatogastroenterology 2011 Nov-Dec;58(112):2012-4. doi: 10.5754/hge11274. PMID: 22024073
Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, Heinrich MC, Tuveson DA, Singer S, Janicek M, Fletcher JA, Silverman SG, Silberman SL, Capdeville R, Kiese B, Peng B, Dimitrijevic S, Druker BJ, Corless C, Fletcher CD, Joensuu H
N Engl J Med 2002 Aug 15;347(7):472-80. doi: 10.1056/NEJMoa020461. PMID: 12181401

Prognosis

Gómez-Peregrina D, Cicala CM, Serrano C
Curr Opin Oncol 2024 Jul 1;36(4):282-290. Epub 2024 Apr 19 doi: 10.1097/CCO.0000000000001040. PMID: 38726808
Serrano C, Bauer S, Gómez-Peregrina D, Kang YK, Jones RL, Rutkowski P, Mir O, Heinrich MC, Tap WD, Newberry K, Grassian A, Shi H, Bialick S, Schöffski P, Pantaleo MA, von Mehren M, Trent JC, George S
Ann Oncol 2023 Jul;34(7):615-625. Epub 2023 Apr 25 doi: 10.1016/j.annonc.2023.04.006. PMID: 37105265Free PMC Article
Fu J, Fang MJ, Dong D, Li J, Sun YS, Tian J, Tang L
Eur J Radiol 2020 Apr;125:108825. Epub 2020 Jan 30 doi: 10.1016/j.ejrad.2020.108825. PMID: 32035324
Serrano C, García-Del-Muro X, Valverde C, Sebio A, Durán J, Manzano A, Pajares I, Hindi N, Landolfi S, Jiménez L, Rubió-Casadevall J, Estival A, Lavernia J, Safont MJ, Pericay C, Díaz-Beveridge R, Martínez-Marín V, Vicente-Baz D, Vivancos A, Hernández-Losa J, Arribas J, Carles J
Oncologist 2019 May;24(5):680-687. Epub 2018 Aug 20 doi: 10.1634/theoncologist.2018-0032. PMID: 30126859Free PMC Article
Raut CP, Wang Q, Manola J, Morgan JA, George S, Wagner AJ, Butrynski JE, Fletcher CD, Demetri GD, Bertagnolli MM
Ann Surg Oncol 2010 Feb;17(2):407-15. Epub 2009 Nov 7 doi: 10.1245/s10434-009-0784-y. PMID: 19898902

Clinical prediction guides

Gómez-Peregrina D, Cicala CM, Serrano C
Curr Opin Oncol 2024 Jul 1;36(4):282-290. Epub 2024 Apr 19 doi: 10.1097/CCO.0000000000001040. PMID: 38726808
Raghavan K, Flavell RR, Westphalen AC, Behr SC
Clin Nucl Med 2021 Apr 1;46(4):345-347. doi: 10.1097/RLU.0000000000003426. PMID: 33234933
Fu J, Fang MJ, Dong D, Li J, Sun YS, Tian J, Tang L
Eur J Radiol 2020 Apr;125:108825. Epub 2020 Jan 30 doi: 10.1016/j.ejrad.2020.108825. PMID: 32035324
Serrano C, García-Del-Muro X, Valverde C, Sebio A, Durán J, Manzano A, Pajares I, Hindi N, Landolfi S, Jiménez L, Rubió-Casadevall J, Estival A, Lavernia J, Safont MJ, Pericay C, Díaz-Beveridge R, Martínez-Marín V, Vicente-Baz D, Vivancos A, Hernández-Losa J, Arribas J, Carles J
Oncologist 2019 May;24(5):680-687. Epub 2018 Aug 20 doi: 10.1634/theoncologist.2018-0032. PMID: 30126859Free PMC Article
Dizdar O, Yalcin S
Hepatogastroenterology 2011 Nov-Dec;58(112):2012-4. doi: 10.5754/hge11274. PMID: 22024073

Recent systematic reviews

Lebellec L, Defachelles AS, Cren PY, Penel N
Acta Oncol 2020 Sep;59(9):1084-1090. Epub 2020 May 13 doi: 10.1080/0284186X.2020.1759825. PMID: 32400254
Cirocchi R, Farinella E, La Mura F, Cavaliere D, Avenia N, Verdecchia GM, Giustozzi G, Noya G, Sciannameo F
Tumori 2010 May-Jun;96(3):392-9. doi: 10.1177/030089161009600303. PMID: 20845798

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