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Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm

MedGen UID:
1654847
Concept ID:
C4744570
Neoplastic Process

Definition

Blastic plasmacytoid dendritic cell neoplasm that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Blastic Plasmacytoid Dendritic Cell Neoplasm

Professional guidelines

PubMed

Hu X, Ediriwickrema A, Saleem A, Tan B, Pemmaraju N, Mannis GN
Leuk Res 2024 Apr;139:107479. Epub 2024 Mar 11 doi: 10.1016/j.leukres.2024.107479. PMID: 38492495

Recent clinical studies

Etiology

Cuglievan B, Connors J, He J, Khazal S, Yedururi S, Dai J, Garces S, Quesada AE, Roth M, Garcia M, McCall D, Gibson A, Ragoonanan D, Petropoulos D, Tewari P, Nunez C, Mahadeo KM, Tasian SK, Lamble AJ, Pawlowska A, Hammond D, Maiti A, Haddad FG, Senapati J, Daver N, Gangat N, Konopleva M, Meshinchi S, Pemmaraju N
Leukemia 2023 Sep;37(9):1767-1778. Epub 2023 Jul 14 doi: 10.1038/s41375-023-01968-z. PMID: 37452102Free PMC Article
Pemmaraju N, Kantarjian H, Sweet K, Wang E, Senapati J, Wilson NR, Konopleva M, Frankel AE, Gupta V, Mesa R, Ulrickson M, Gorak E, Bhatia S, Budak-Alpdogan T, Mason J, Garcia-Romero MT, Lopez-Santiago N, Cesarman-Maus G, Vachhani P, Lee S, Bhatt VR, Blum W, Walter RB, Bixby D, Gojo I, Duvic M, Rampal RK, de Lima M, Foran J, Fathi AT, Hall AC, Jacoby MA, Lancet J, Mannis G, Stein AS, Mims A, Rizzieri D, Olin R, Perl A, Schiller G, Shami P, Stone RM, Strickland S, Wieduwilt MJ, Daver N, Ravandi F, Vasu S, Guzman M, Roboz GJ, Khoury J, Qazilbash M, Aung PP, Cuglievan B, Madanat Y, Kharfan-Dabaja MA, Pawlowska A, Taylor J, Tallman M, Dhakal P, Lane AA
Blood 2023 Feb 9;141(6):567-578. doi: 10.1182/blood.2022017865. PMID: 36399715
Pemmaraju N, Sweet KL, Stein AS, Wang ES, Rizzieri DA, Vasu S, Rosenblat TL, Brooks CL, Habboubi N, Mughal TI, Kantarjian H, Konopleva M, Lane AA
J Clin Oncol 2022 Sep 10;40(26):3032-3036. Epub 2022 Jul 12 doi: 10.1200/JCO.22.00034. PMID: 35820082Free PMC Article
Li Y, Sun V, Sun W, Pawlowska A
Hematol Oncol Clin North Am 2020 Jun;34(3):601-612. Epub 2020 Mar 9 doi: 10.1016/j.hoc.2020.01.008. PMID: 32336423
DiNardo CD, Rausch CR, Benton C, Kadia T, Jain N, Pemmaraju N, Daver N, Covert W, Marx KR, Mace M, Jabbour E, Cortes J, Garcia-Manero G, Ravandi F, Bhalla KN, Kantarjian H, Konopleva M
Am J Hematol 2018 Mar;93(3):401-407. Epub 2017 Dec 23 doi: 10.1002/ajh.25000. PMID: 29218851

Diagnosis

Pemmaraju N, Deconinck E, Mehta P, Walker I, Herling M, Garnache-Ottou F, Gabarin N, Campbell CJV, Duell J, Moshe Y, Mughal T, Mohty M, Angelucci E
Clin Lymphoma Myeloma Leuk 2024 Apr;24(4):e130-e137. Epub 2023 Dec 20 doi: 10.1016/j.clml.2023.12.010. PMID: 38267355
Cuglievan B, Connors J, He J, Khazal S, Yedururi S, Dai J, Garces S, Quesada AE, Roth M, Garcia M, McCall D, Gibson A, Ragoonanan D, Petropoulos D, Tewari P, Nunez C, Mahadeo KM, Tasian SK, Lamble AJ, Pawlowska A, Hammond D, Maiti A, Haddad FG, Senapati J, Daver N, Gangat N, Konopleva M, Meshinchi S, Pemmaraju N
Leukemia 2023 Sep;37(9):1767-1778. Epub 2023 Jul 14 doi: 10.1038/s41375-023-01968-z. PMID: 37452102Free PMC Article
Wang Y, Xiao L, Yin L, Zhou L, Deng Y, Deng H
Medicine (Baltimore) 2023 Feb 17;102(7):e32904. doi: 10.1097/MD.0000000000032904. PMID: 36800625Free PMC Article
Wilson NR, Konopleva M, Khoury JD, Pemmaraju N
Clin Lymphoma Myeloma Leuk 2021 Nov;21(11):734-740. Epub 2021 Jun 10 doi: 10.1016/j.clml.2021.05.018. PMID: 34226167
Li Y, Sun V, Sun W, Pawlowska A
Hematol Oncol Clin North Am 2020 Jun;34(3):601-612. Epub 2020 Mar 9 doi: 10.1016/j.hoc.2020.01.008. PMID: 32336423

Therapy

Pemmaraju N, Deconinck E, Mehta P, Walker I, Herling M, Garnache-Ottou F, Gabarin N, Campbell CJV, Duell J, Moshe Y, Mughal T, Mohty M, Angelucci E
Clin Lymphoma Myeloma Leuk 2024 Apr;24(4):e130-e137. Epub 2023 Dec 20 doi: 10.1016/j.clml.2023.12.010. PMID: 38267355
Pemmaraju N, Sweet KL, Stein AS, Wang ES, Rizzieri DA, Vasu S, Rosenblat TL, Brooks CL, Habboubi N, Mughal TI, Kantarjian H, Konopleva M, Lane AA
J Clin Oncol 2022 Sep 10;40(26):3032-3036. Epub 2022 Jul 12 doi: 10.1200/JCO.22.00034. PMID: 35820082Free PMC Article
Adimora IJ, Wilson NR, Pemmaraju N
Cancer 2022 Aug 15;128(16):3019-3026. Epub 2022 Jun 21 doi: 10.1002/cncr.34345. PMID: 35726525
DiNardo CD, Rausch CR, Benton C, Kadia T, Jain N, Pemmaraju N, Daver N, Covert W, Marx KR, Mace M, Jabbour E, Cortes J, Garcia-Manero G, Ravandi F, Bhalla KN, Kantarjian H, Konopleva M
Am J Hematol 2018 Mar;93(3):401-407. Epub 2017 Dec 23 doi: 10.1002/ajh.25000. PMID: 29218851
Sullivan JM, Rizzieri DA
Hematology Am Soc Hematol Educ Program 2016 Dec 2;2016(1):16-23. doi: 10.1182/asheducation-2016.1.16. PMID: 27913457Free PMC Article

Prognosis

Pemmaraju N, Deconinck E, Mehta P, Walker I, Herling M, Garnache-Ottou F, Gabarin N, Campbell CJV, Duell J, Moshe Y, Mughal T, Mohty M, Angelucci E
Clin Lymphoma Myeloma Leuk 2024 Apr;24(4):e130-e137. Epub 2023 Dec 20 doi: 10.1016/j.clml.2023.12.010. PMID: 38267355
Wang Y, Xiao L, Yin L, Zhou L, Deng Y, Deng H
Medicine (Baltimore) 2023 Feb 17;102(7):e32904. doi: 10.1097/MD.0000000000032904. PMID: 36800625Free PMC Article
Pemmaraju N, Sweet KL, Stein AS, Wang ES, Rizzieri DA, Vasu S, Rosenblat TL, Brooks CL, Habboubi N, Mughal TI, Kantarjian H, Konopleva M, Lane AA
J Clin Oncol 2022 Sep 10;40(26):3032-3036. Epub 2022 Jul 12 doi: 10.1200/JCO.22.00034. PMID: 35820082Free PMC Article
Adimora IJ, Wilson NR, Pemmaraju N
Cancer 2022 Aug 15;128(16):3019-3026. Epub 2022 Jun 21 doi: 10.1002/cncr.34345. PMID: 35726525
Wilson NR, Konopleva M, Khoury JD, Pemmaraju N
Clin Lymphoma Myeloma Leuk 2021 Nov;21(11):734-740. Epub 2021 Jun 10 doi: 10.1016/j.clml.2021.05.018. PMID: 34226167

Clinical prediction guides

Pemmaraju N, Sweet KL, Stein AS, Wang ES, Rizzieri DA, Vasu S, Rosenblat TL, Brooks CL, Habboubi N, Mughal TI, Kantarjian H, Konopleva M, Lane AA
J Clin Oncol 2022 Sep 10;40(26):3032-3036. Epub 2022 Jul 12 doi: 10.1200/JCO.22.00034. PMID: 35820082Free PMC Article
Pemmaraju N, Konopleva M
Blood Adv 2020 Aug 25;4(16):4020-4027. doi: 10.1182/bloodadvances.2019000173. PMID: 32841341Free PMC Article
Cernan M, Szotkowski T, Hisemova M, Cetkovsky P, Sramkova L, Stary J, Racil Z, Mayer J, Sramek J, Jindra P, Visek B, Zak P, Novak J, Kozak T, Furst T, Papajik T
Neoplasma 2020 May;67(3):650-659. Epub 2020 Feb 17 doi: 10.4149/neo_2020_190507N407. PMID: 32064883
DiNardo CD, Rausch CR, Benton C, Kadia T, Jain N, Pemmaraju N, Daver N, Covert W, Marx KR, Mace M, Jabbour E, Cortes J, Garcia-Manero G, Ravandi F, Bhalla KN, Kantarjian H, Konopleva M
Am J Hematol 2018 Mar;93(3):401-407. Epub 2017 Dec 23 doi: 10.1002/ajh.25000. PMID: 29218851
Montero J, Stephansky J, Cai T, Griffin GK, Cabal-Hierro L, Togami K, Hogdal LJ, Galinsky I, Morgan EA, Aster JC, Davids MS, LeBoeuf NR, Stone RM, Konopleva M, Pemmaraju N, Letai A, Lane AA
Cancer Discov 2017 Feb;7(2):156-164. Epub 2016 Dec 16 doi: 10.1158/2159-8290.CD-16-0999. PMID: 27986708Free PMC Article

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