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Infantile constant esotropia

MedGen UID:
1640706
Concept ID:
C4703529
Finding
Synonym: Infantile (constant) esotropia
 
HPO: HP:0031761

Definition

Constant esotropia occurring before 6 months of age. It is typically associated with a large angle of deviation, alternating fixation (therefore low risk of amblyopia) and poor potential for binocular single vision. Other features that might be present in individuals with infantile (constant) esotropia include latent nystagmus or manifest latent nystagmus, dissociated vertical divergence, cyclotropia, abnormal head posture, limited abduction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfantile constant esotropia

Recent clinical studies

Etiology

Mohan K, Sharma SK
J Pediatr Ophthalmol Strabismus 2024 Mar-Apr;61(2):106-113. Epub 2023 Aug 24 doi: 10.3928/01913913-20230721-01. PMID: 37615418
Rajavi Z, Sabbaghi H, Behradfar N, Abdi S, Bahraini R, Kheiri B, Sheibani K
Korean J Ophthalmol 2020 Apr;34(2):143-149. doi: 10.3341/kjo.2019.0090. PMID: 32233148Free PMC Article
Voide N, Robert MP
Eye (Lond) 2018 Jul;32(7):1197-1200. Epub 2018 Mar 2 doi: 10.1038/s41433-018-0060-0. PMID: 29497134Free PMC Article
Kelly KR, Felius J, Ramachandran S, John BA, Jost RM, Birch EE
Invest Ophthalmol Vis Sci 2016 May 1;57(6):2545-51. doi: 10.1167/iovs.15-18606. PMID: 27159445Free PMC Article
Shauly Y, Miller B, Meyer E
J Pediatr Ophthalmol Strabismus 1997 Nov-Dec;34(6):357-64. doi: 10.3928/0191-3913-19971101-07. PMID: 9430062

Diagnosis

Yeo DCM, Davies R, Watkins WJ, Watts P
Eye (Lond) 2024 Mar;38(4):680-686. Epub 2024 Feb 2 doi: 10.1038/s41433-023-02901-5. PMID: 38302533Free PMC Article
Bagheri M, Farvardin M
J AAPOS 2018 Jun;22(3):167-169.e1. Epub 2018 Mar 8 doi: 10.1016/j.jaapos.2017.12.004. PMID: 29526714
Kelly KR, Felius J, Ramachandran S, John BA, Jost RM, Birch EE
Invest Ophthalmol Vis Sci 2016 May 1;57(6):2545-51. doi: 10.1167/iovs.15-18606. PMID: 27159445Free PMC Article
Hunter DG, Ellis FJ
Ophthalmology 1999 Oct;106(10):1951-6. doi: 10.1016/S0161-6420(99)90407-4. PMID: 10519591
Biglan AW, Davis JS, Cheng KP, Pettapiece MC
J Pediatr Ophthalmol Strabismus 1996 Mar-Apr;33(2):79-84. doi: 10.3928/0191-3913-19960301-04. PMID: 8965243

Therapy

Yeo DCM, Davies R, Watkins WJ, Watts P
Eye (Lond) 2024 Mar;38(4):680-686. Epub 2024 Feb 2 doi: 10.1038/s41433-023-02901-5. PMID: 38302533Free PMC Article
Hunter DG, Ellis FJ
Ophthalmology 1999 Oct;106(10):1951-6. doi: 10.1016/S0161-6420(99)90407-4. PMID: 10519591
Birch E, Stager D, Wright K, Beck R
J AAPOS 1998 Dec;2(6):325-8; discussion 329. doi: 10.1016/s1091-8531(98)90026-x. PMID: 10532717

Prognosis

Yeo DCM, Davies R, Watkins WJ, Watts P
Eye (Lond) 2024 Mar;38(4):680-686. Epub 2024 Feb 2 doi: 10.1038/s41433-023-02901-5. PMID: 38302533Free PMC Article
Mohan K, Sharma SK
J Pediatr Ophthalmol Strabismus 2024 Mar-Apr;61(2):106-113. Epub 2023 Aug 24 doi: 10.3928/01913913-20230721-01. PMID: 37615418
Rajavi Z, Sabbaghi H, Behradfar N, Abdi S, Bahraini R, Kheiri B, Sheibani K
Korean J Ophthalmol 2020 Apr;34(2):143-149. doi: 10.3341/kjo.2019.0090. PMID: 32233148Free PMC Article
Shauly Y, Miller B, Meyer E
J Pediatr Ophthalmol Strabismus 1997 Nov-Dec;34(6):357-64. doi: 10.3928/0191-3913-19971101-07. PMID: 9430062
Foster RS, Paul TO, Jampolsky A
Am J Ophthalmol 1976 Aug;82(2):291-9. doi: 10.1016/0002-9394(76)90436-0. PMID: 949082

Clinical prediction guides

Yeo DCM, Davies R, Watkins WJ, Watts P
Eye (Lond) 2024 Mar;38(4):680-686. Epub 2024 Feb 2 doi: 10.1038/s41433-023-02901-5. PMID: 38302533Free PMC Article
Mohan K, Sharma SK
J Pediatr Ophthalmol Strabismus 2024 Mar-Apr;61(2):106-113. Epub 2023 Aug 24 doi: 10.3928/01913913-20230721-01. PMID: 37615418
Rajavi Z, Sabbaghi H, Behradfar N, Abdi S, Bahraini R, Kheiri B, Sheibani K
Korean J Ophthalmol 2020 Apr;34(2):143-149. doi: 10.3341/kjo.2019.0090. PMID: 32233148Free PMC Article
Wong AM
Can J Ophthalmol 2008 Dec;43(6):643-51. doi: 10.3129/i08-115. PMID: 19020629Free PMC Article
Hunter DG, Ellis FJ
Ophthalmology 1999 Oct;106(10):1951-6. doi: 10.1016/S0161-6420(99)90407-4. PMID: 10519591

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