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Refractory Peripheral Primitive Neuroectodermal Tumor

MedGen UID:
1639124
Concept ID:
C4684863
Neoplastic Process

Definition

Peripheral primitive neuroectodermal tumor that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Peripheral Primitive Neuroectodermal Tumor

Professional guidelines

PubMed

Chou SW, Chang HH
Cancer Lett 2024 Apr 28;588:216617. Epub 2024 Feb 2 doi: 10.1016/j.canlet.2024.216617. PMID: 38311055
Nysom K, Morad AG, Rafael MS, Zier J, Marachelian A, Watt T, Morgenstern DA
Pediatr Blood Cancer 2023 May;70(5):e30217. Epub 2023 Feb 11 doi: 10.1002/pbc.30217. PMID: 36772891
Heaton TE, Davidoff AM
Semin Pediatr Surg 2016 Oct;25(5):311-317. Epub 2016 Sep 3 doi: 10.1053/j.sempedsurg.2016.09.001. PMID: 27955735Free PMC Article

Recent clinical studies

Etiology

Qiu B, Matthay KK
Nat Rev Clin Oncol 2022 Aug;19(8):515-533. Epub 2022 May 25 doi: 10.1038/s41571-022-00643-z. PMID: 35614230
DuBois SG, Macy ME, Henderson TO
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-13. doi: 10.1200/EDBK_349783. PMID: 35522915
Rafael MS, Cohen-Gogo S, Irwin MS, Vali R, Shammas A, Morgenstern DA
PET Clin 2021 Jul;16(3):419-427. doi: 10.1016/j.cpet.2021.03.006. PMID: 34053585
Markham A
Drugs 2021 Feb;81(2):291-296. doi: 10.1007/s40265-021-01467-4. PMID: 33616889
Schengrund CL
Int J Mol Sci 2020 Jul 27;21(15) doi: 10.3390/ijms21155313. PMID: 32726962Free PMC Article

Diagnosis

Borankova K, Krchniakova M, Leck LYW, Kubistova A, Neradil J, Jansson PJ, Hogarty MD, Skoda J
Cell Death Dis 2023 Nov 16;14(11):747. doi: 10.1038/s41419-023-06278-x. PMID: 37973789Free PMC Article
DuBois SG, Macy ME, Henderson TO
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-13. doi: 10.1200/EDBK_349783. PMID: 35522915
Rafael MS, Cohen-Gogo S, Irwin MS, Vali R, Shammas A, Morgenstern DA
PET Clin 2021 Jul;16(3):419-427. doi: 10.1016/j.cpet.2021.03.006. PMID: 34053585
Schengrund CL
Int J Mol Sci 2020 Jul 27;21(15) doi: 10.3390/ijms21155313. PMID: 32726962Free PMC Article
Jubierre L, Jiménez C, Rovira E, Soriano A, Sábado C, Gros L, Llort A, Hladun R, Roma J, Toledo JS, Gallego S, Segura MF
Exp Mol Med 2018 Apr 27;50(4):1-12. doi: 10.1038/s12276-018-0077-2. PMID: 29700278Free PMC Article

Therapy

Nysom K, Morad AG, Rafael MS, Zier J, Marachelian A, Watt T, Morgenstern DA
Pediatr Blood Cancer 2023 May;70(5):e30217. Epub 2023 Feb 11 doi: 10.1002/pbc.30217. PMID: 36772891
Qiu B, Matthay KK
Nat Rev Clin Oncol 2022 Aug;19(8):515-533. Epub 2022 May 25 doi: 10.1038/s41571-022-00643-z. PMID: 35614230
DuBois SG, Macy ME, Henderson TO
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-13. doi: 10.1200/EDBK_349783. PMID: 35522915
Markham A
Drugs 2021 Feb;81(2):291-296. doi: 10.1007/s40265-021-01467-4. PMID: 33616889
Rodríguez-Nogales C, Noguera R, Couvreur P, Blanco-Prieto MJ
J Pharmacol Exp Ther 2019 Sep;370(3):625-635. Epub 2019 Jan 11 doi: 10.1124/jpet.118.255067. PMID: 30635473

Prognosis

Qiu B, Matthay KK
Nat Rev Clin Oncol 2022 Aug;19(8):515-533. Epub 2022 May 25 doi: 10.1038/s41571-022-00643-z. PMID: 35614230
DuBois SG, Macy ME, Henderson TO
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-13. doi: 10.1200/EDBK_349783. PMID: 35522915
Schengrund CL
Int J Mol Sci 2020 Jul 27;21(15) doi: 10.3390/ijms21155313. PMID: 32726962Free PMC Article
Lange I, Koster J, Koomoa DT
Cell Calcium 2019 Sep;82:102052. Epub 2019 Jun 17 doi: 10.1016/j.ceca.2019.06.006. PMID: 31306997
Smith NM, Carli MM, Hanieh A, Clark B, Bourne AJ, Byard RW
Childs Nerv Syst 1992 Aug;8(5):258-62. doi: 10.1007/BF00300792. PMID: 1394264

Clinical prediction guides

De Ioris MA, Fabozzi F, Del Bufalo F, Del Baldo G, Villani MF, Cefalo MG, Garganese MC, Stracuzzi A, Tangari F, Greco AM, Giovannoni I, Carta R, D'Andrea ML, Mastronuzzi A, Locatelli F
Sci Rep 2023 Nov 7;13(1):19295. doi: 10.1038/s41598-023-44993-9. PMID: 37935707Free PMC Article
Guo X, Chang M, Wang Y, Xing B, Ma W
Int J Biol Sci 2023;19(12):3762-3780. Epub 2023 Jul 24 doi: 10.7150/ijbs.85813. PMID: 37564196Free PMC Article
Del Bufalo F, De Angelis B, Caruana I, Del Baldo G, De Ioris MA, Serra A, Mastronuzzi A, Cefalo MG, Pagliara D, Amicucci M, Li Pira G, Leone G, Bertaina V, Sinibaldi M, Di Cecca S, Guercio M, Abbaszadeh Z, Iaffaldano L, Gunetti M, Iacovelli S, Bugianesi R, Macchia S, Algeri M, Merli P, Galaverna F, Abbas R, Garganese MC, Villani MF, Colafati GS, Bonetti F, Rabusin M, Perruccio K, Folsi V, Quintarelli C, Locatelli F; Precision Medicine Team–IRCCS Ospedale Pediatrico Bambino Gesù
N Engl J Med 2023 Apr 6;388(14):1284-1295. doi: 10.1056/NEJMoa2210859. PMID: 37018492
Schengrund CL
Int J Mol Sci 2020 Jul 27;21(15) doi: 10.3390/ijms21155313. PMID: 32726962Free PMC Article
Morgenstern DA, Baruchel S, Irwin MS
J Pediatr Hematol Oncol 2013 Jul;35(5):337-47. doi: 10.1097/MPH.0b013e318299d637. PMID: 23703550

Recent systematic reviews

Herd F, Basta NO, McNally RJQ, Tweddle DA
Eur J Cancer 2019 Apr;111:50-58. Epub 2019 Feb 26 doi: 10.1016/j.ejca.2018.12.032. PMID: 30822684Free PMC Article
Wilson JS, Gains JE, Moroz V, Wheatley K, Gaze MN
Eur J Cancer 2014 Mar;50(4):801-15. Epub 2013 Dec 12 doi: 10.1016/j.ejca.2013.11.016. PMID: 24333097

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