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Grade 2 Small Intestinal Obstruction, CTCAE

MedGen UID:
1638830
•Concept ID:
C4688541
•
Finding

Definition

Symptomatic; altered GI function; limiting instrumental ADL [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 2 Small Intestinal Obstruction, CTCAE

Recent clinical studies

Etiology

SAKK 19/17: safety analysis of first-line durvalumab in patients with PD-L1 positive, advanced nonsmall cell lung cancer and a performance status of 2.
Mark M, Froesch P, Eboulet EI, Addeo A, Pless M, Rothschild SI, Janthur WD, Burmeister H, Friedlaender A, Schneider M, Metaxas Y, Joerger M, Wannesson L, Schwitter M, Baudoux N, Weindler S, Biaggi-Rudolf C, Früh M; Swiss Group for Clinical Cancer Research (SAKK)
Cancer Immunol Immunother 2021 May;70(5):1255-1262. Epub 2020 Nov 1 doi: 10.1007/s00262-020-02757-8. PMID: 33130956Free PMC Article
Induction chemotherapy with cetuximab, vinorelbine-cisplatin followed by thoracic radiotherapy and concurrent cetuximab, vinorelbine-cisplatin in patients with unresectable stage III non-small cell lung cancer.
Liu D, Zheng X, Chen J, Liu G, Xu Y, Shen Y, Xie L, Zhao W, Jiang G, Fan M
Lung Cancer 2015 Sep;89(3):249-54. Epub 2015 Jun 17 doi: 10.1016/j.lungcan.2015.06.004. PMID: 26118463

Therapy

SAKK 19/17: safety analysis of first-line durvalumab in patients with PD-L1 positive, advanced nonsmall cell lung cancer and a performance status of 2.
Mark M, Froesch P, Eboulet EI, Addeo A, Pless M, Rothschild SI, Janthur WD, Burmeister H, Friedlaender A, Schneider M, Metaxas Y, Joerger M, Wannesson L, Schwitter M, Baudoux N, Weindler S, Biaggi-Rudolf C, Früh M; Swiss Group for Clinical Cancer Research (SAKK)
Cancer Immunol Immunother 2021 May;70(5):1255-1262. Epub 2020 Nov 1 doi: 10.1007/s00262-020-02757-8. PMID: 33130956Free PMC Article
A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses.
Matei D, Ghamande S, Roman L, Alvarez Secord A, Nemunaitis J, Markham MJ, Nephew KP, Jueliger S, Oganesian A, Naim S, Su XY, Keer H, Azab M, Fleming GF
Clin Cancer Res 2018 May 15;24(10):2285-2293. Epub 2018 Mar 2 doi: 10.1158/1078-0432.CCR-17-3055. PMID: 29500276Free PMC Article
Induction chemotherapy with cetuximab, vinorelbine-cisplatin followed by thoracic radiotherapy and concurrent cetuximab, vinorelbine-cisplatin in patients with unresectable stage III non-small cell lung cancer.
Liu D, Zheng X, Chen J, Liu G, Xu Y, Shen Y, Xie L, Zhao W, Jiang G, Fan M
Lung Cancer 2015 Sep;89(3):249-54. Epub 2015 Jun 17 doi: 10.1016/j.lungcan.2015.06.004. PMID: 26118463

Clinical prediction guides

SAKK 19/17: safety analysis of first-line durvalumab in patients with PD-L1 positive, advanced nonsmall cell lung cancer and a performance status of 2.
Mark M, Froesch P, Eboulet EI, Addeo A, Pless M, Rothschild SI, Janthur WD, Burmeister H, Friedlaender A, Schneider M, Metaxas Y, Joerger M, Wannesson L, Schwitter M, Baudoux N, Weindler S, Biaggi-Rudolf C, Früh M; Swiss Group for Clinical Cancer Research (SAKK)
Cancer Immunol Immunother 2021 May;70(5):1255-1262. Epub 2020 Nov 1 doi: 10.1007/s00262-020-02757-8. PMID: 33130956Free PMC Article
A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses.
Matei D, Ghamande S, Roman L, Alvarez Secord A, Nemunaitis J, Markham MJ, Nephew KP, Jueliger S, Oganesian A, Naim S, Su XY, Keer H, Azab M, Fleming GF
Clin Cancer Res 2018 May 15;24(10):2285-2293. Epub 2018 Mar 2 doi: 10.1158/1078-0432.CCR-17-3055. PMID: 29500276Free PMC Article

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