Fungal infection of central nervous system

MedGen UID:: 152666
•Concept ID:: C0729544
•: Disease or Syndrome

Synonyms:	Central Nervous System Fungal Infections; Central Nervous System Mycoses; CNS Fungal Infection; CNS Fungal Infections; Fungal Infection, CNS; Fungal Infections, Central Nervous System; Fungal Infections, CNS; Infection, CNS Fungal; Infections, CNS Fungal; Infections, Fungal, Central Nervous System; Mycoses, Central Nervous System
SNOMED CT:	Fungal central nervous system infection (128120005); Fungal infection of central nervous system (128120005)

Definition

MYCOSES of the brain, spinal cord, and meninges which may result in ENCEPHALITIS; MENINGITIS, FUNGAL; MYELITIS; BRAIN ABSCESS; and EPIDURAL ABSCESS. Certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME). [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVFungal infection of central nervous system

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Cause
    - Infection
      - Bacterial Infections and Mycoses
        Fungal infectious disease
        Fungal infection of central nervous system
        Fungal meningitis
        Coccidioidal meningitis
        Cryptococcal meningitis
        Neuroaspergillosis

Professional guidelines

PubMed

Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.

Chang CC, Harrison TS, Bicanic TA, Chayakulkeeree M, Sorrell TC, Warris A, Hagen F, Spec A, Oladele R, Govender NP, Chen SC, Mody CH, Groll AH, Chen YC, Lionakis MS, Alanio A, Castañeda E, Lizarazo J, Vidal JE, Takazono T, Hoenigl M, Alffenaar JW, Gangneux JP, Soman R, Zhu LP, Bonifaz A, Jarvis JN, Day JN, Klimko N, Salmanton-García J, Jouvion G, Meya DB, Lawrence D, Rahn S, Bongomin F, McMullan BJ, Sprute R, Nyazika TK, Beardsley J, Carlesse F, Heath CH, Ayanlowo OO, Mashedi OM, Queiroz-Telles Filho F, Hosseinipour MC, Patel AK, Temfack E, Singh N, Cornely OA, Boulware DR, Lortholary O, Pappas PG, Perfect JR
Lancet Infect Dis 2024 Aug;24(8):e495-e512. Epub 2024 Feb 9 doi: 10.1016/S1473-3099(23)00731-4. PMID: 38346436 Free PMC Article

Diagnosis and management of cryptococcal meningitis in HIV-infected adults.

McHale TC, Boulware DR, Kasibante J, Ssebambulidde K, Skipper CP, Abassi M
Clin Microbiol Rev 2023 Dec 20;36(4):e0015622. Epub 2023 Nov 28 doi: 10.1128/cmr.00156-22. PMID: 38014977 Free PMC Article

Clinical management of infectious cerebral vasculitides.

Carod Artal FJ
Expert Rev Neurother 2016;16(2):205-21. Epub 2016 Jan 19 doi: 10.1586/14737175.2015.1134321. PMID: 26689107

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