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Scrotum squamous cell carcinoma

MedGen UID:
138101
Concept ID:
C0349551
Neoplastic Process
Synonyms: Scrotal Squamous Cell Carcinoma; scrotal squamous cell carcinoma; scrotum squamous cell carcinoma; Squamous cell carcinoma of scrotum; Squamous Cell Carcinoma of Scrotum; squamous cell carcinoma of scrotum; Squamous Cell Carcinoma of the Scrotum; squamous cell carcinoma of the scrotum
SNOMED CT: Squamous cell carcinoma of scrotum (276860003)
 
Monarch Initiative: MONDO:0001651

Definition

A rare squamous cell carcinoma that arises from the scrotum. It has been associated with exposure to environmental and industrial carcinogens. The prognosis depends on the extent of lymph node involvement. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVScrotum squamous cell carcinoma

Professional guidelines

PubMed

Huang JH, Broggi M, Osunkoya AO, Master VA
Urol Clin North Am 2016 Nov;43(4):531-544. Epub 2016 Sep 3 doi: 10.1016/j.ucl.2016.06.014. PMID: 27717439
Zhu Y, Ye DW
Urol Clin North Am 2016 Nov;43(4):523-530. doi: 10.1016/j.ucl.2016.06.013. PMID: 27717438
Ichikawa T, Nakano I, Hirokawa I
J Urol 1969 Dec;102(6):699-707. doi: 10.1016/s0022-5347(17)62235-3. PMID: 5392743

Recent clinical studies

Etiology

Pang KH, Fallara G, Tang S, Haider A, Freeman A, Hadway P, Nigam R, Rees R, Mitra A, Alifrangis C, Bunker C, Alnajjar HM, Muneer A
Urol Oncol 2023 Dec;41(12):488.e11-488.e18. Epub 2023 Oct 29 doi: 10.1016/j.urolonc.2023.08.006. PMID: 37903660
Menon S, Moch H, Berney DM, Cree IA, Srigley JR, Tsuzuki T, Compérat E, Hartmann A, Netto G, Rubin MA, Gill AJ, Turajlic S, Tan PH, Raspollini MR, Tickoo SK, Amin MB
Histopathology 2023 Mar;82(4):508-520. Epub 2022 Nov 9 doi: 10.1111/his.14824. PMID: 36221864
Michalová K, Beniač P, Kacerovská D
Cesk Patol 2022 Fall;67(4):192-197. PMID: 36513504
Moch H, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Netto GJ
Eur Urol 2022 Nov;82(5):458-468. Epub 2022 Jul 16 doi: 10.1016/j.eururo.2022.06.016. PMID: 35853783
Huang JH, Broggi M, Osunkoya AO, Master VA
Urol Clin North Am 2016 Nov;43(4):531-544. Epub 2016 Sep 3 doi: 10.1016/j.ucl.2016.06.014. PMID: 27717439

Diagnosis

Pang KH, Fallara G, Tang S, Haider A, Freeman A, Hadway P, Nigam R, Rees R, Mitra A, Alifrangis C, Bunker C, Alnajjar HM, Muneer A
Urol Oncol 2023 Dec;41(12):488.e11-488.e18. Epub 2023 Oct 29 doi: 10.1016/j.urolonc.2023.08.006. PMID: 37903660
Moch H, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Netto GJ
Eur Urol 2022 Nov;82(5):458-468. Epub 2022 Jul 16 doi: 10.1016/j.eururo.2022.06.016. PMID: 35853783
Hartman R, Chu J, Patel R, Meehan S, Stein JA
Dermatol Online J 2011 Oct 15;17(10):4. PMID: 22031630
Lowe FC
J Urol 1983 Sep;130(3):423-7. doi: 10.1016/s0022-5347(17)51233-1. PMID: 6350613
McDonald MW
Urology 1982 Mar;19(3):269-74. doi: 10.1016/0090-4295(82)90497-6. PMID: 7064253

Therapy

Abate D, Giusti G, Caria N, De Vita G, Lucci Chiarissi M, De Lisa A
Arch Ital Urol Androl 2018 Jun 30;90(2):141-142. doi: 10.4081/aiua.2018.2.141. PMID: 29974731
Narang T, Manhas A, Kumar B
Skinmed 2017;15(1):73-75. Epub 2017 Feb 1 PMID: 28270316
Arora AK, Kumaran MS, Narang T, Saikia UN, Handa S
Int J STD AIDS 2017 Mar;28(4):411-414. Epub 2016 Aug 20 doi: 10.1177/0956462416665996. PMID: 27535727
Kutlubay Z, Engin B, Zara T, Tüzün Y
Clin Dermatol 2013 Jul-Aug;31(4):362-373. doi: 10.1016/j.clindermatol.2013.01.003. PMID: 23806153
Hartman R, Chu J, Patel R, Meehan S, Stein JA
Dermatol Online J 2011 Oct 15;17(10):4. PMID: 22031630

Prognosis

Sun Y, Miao X, Wang L, Zhang Y, Shen Z
Medicine (Baltimore) 2023 Feb 22;102(8):e32994. doi: 10.1097/MD.0000000000032994. PMID: 36827046Free PMC Article
Menon S, Moch H, Berney DM, Cree IA, Srigley JR, Tsuzuki T, Compérat E, Hartmann A, Netto G, Rubin MA, Gill AJ, Turajlic S, Tan PH, Raspollini MR, Tickoo SK, Amin MB
Histopathology 2023 Mar;82(4):508-520. Epub 2022 Nov 9 doi: 10.1111/his.14824. PMID: 36221864
Huang JH, Broggi M, Osunkoya AO, Master VA
Urol Clin North Am 2016 Nov;43(4):531-544. Epub 2016 Sep 3 doi: 10.1016/j.ucl.2016.06.014. PMID: 27717439
Kutlubay Z, Engin B, Zara T, Tüzün Y
Clin Dermatol 2013 Jul-Aug;31(4):362-373. doi: 10.1016/j.clindermatol.2013.01.003. PMID: 23806153
Shukla CJ, Shabbir M, Feneley MR, Withey S, Muneer A, Minhas S
Clin Oncol (R Coll Radiol) 2010 Nov;22(9):747-54. Epub 2010 Aug 25 doi: 10.1016/j.clon.2010.07.010. PMID: 20800458

Clinical prediction guides

Lee HJ, Lim EJ, Woo SJQ, Aslim EJ, Ng LG, Gan VHL
Clin Transplant 2024 Jul;38(7):e15415. doi: 10.1111/ctr.15415. PMID: 39049619
Cook EE, Harrison BT, Hirsch MS
Histopathology 2023 Jul;83(1):104-108. Epub 2023 Mar 27 doi: 10.1111/his.14908. PMID: 36971374
Du X, Yin X, Zhou N, Zhang G, Shi H, Cao S
J Cutan Pathol 2010 Jun;37(6):683-6. Epub 2009 Jul 14 doi: 10.1111/j.1600-0560.2009.01336.x. PMID: 19615013
Wright JL, Morgan TM, Lin DW
Urology 2008 Nov;72(5):1139-43. Epub 2008 Sep 16 doi: 10.1016/j.urology.2008.06.043. PMID: 18799208
Harris M
Histopathology 1982 Mar;6(2):197-210. doi: 10.1111/j.1365-2559.1982.tb02715.x. PMID: 7076139

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