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Warty dyskeratoma

MedGen UID:
137717
Concept ID:
C0334063
Disease or Syndrome
Synonyms: Follicular Dyskeratoma; Follicular dyskeratoma; follicular dyskeratoma; Isolated Follicular Keratosis; isolated follicular keratosis; Isolated keratosis follicularis; Warty Dyskeratoma; warty dyskeratoma
SNOMED CT: Warty dyskeratoma (22524002); Isolated keratosis follicularis (22524002); Warty dyskeratoma (254676008)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
Monarch Initiative: MONDO:0019077
Orphanet: ORPHA69745

Definition

A rare, benign, epidermal disease characterized by a solitary, asymptomatic, verrucous, skin-coloured to red-brown papule or nodule, which contains a central pore and keratotic plug, occuring most frequently on the scalp, face and neck (rarely, in the mouth, under the nail plate or on the mons pubis). Occasionally, lesions may be multiple and/or pruritic. Histologically, a well-circumscribed, cup-shaped, keratin-filled invagination, with prominent acantholytic dyskeratosis, suprabasilar clefts and villi projecting into the clefts, is observed. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWarty dyskeratoma
Follow this link to review classifications for Warty dyskeratoma in Orphanet.

Recent clinical studies

Etiology

Allon I, Buchner A
J Oral Pathol Med 2012 Mar;41(3):261-7. Epub 2011 Sep 21 doi: 10.1111/j.1600-0714.2011.01082.x. PMID: 21936875
Bergua P, Puig L, Fernández-Figueras MT, Baselga E, Alomar A
Pediatr Dermatol 2003 May-Jun;20(3):262-5. doi: 10.1046/j.1525-1470.2003.20316.x. PMID: 12787279
Leider AS, Eversole LR
Oral Surg Oral Med Oral Pathol 1984 Jul;58(1):64-70. doi: 10.1016/0030-4220(84)90366-9. PMID: 6589580
Duray PH, Merino MJ, Axiotis C
Int J Gynecol Pathol 1983;2(3):286-93. doi: 10.1097/00004347-198303000-00006. PMID: 6642851
Panja RK
J Cutan Pathol 1977 Sep;4(4):194-200. doi: 10.1111/j.1600-0560.1977.tb00908.x. PMID: 591661

Diagnosis

Lee JH, Uh JA, Kim JH, Lee SK, Kim MS, Lee UH
Indian J Pathol Microbiol 2023 Jul-Sep;66(3):659-660. doi: 10.4103/ijpm.ijpm_230_21. PMID: 37530365
Allon I, Buchner A
J Oral Pathol Med 2012 Mar;41(3):261-7. Epub 2011 Sep 21 doi: 10.1111/j.1600-0714.2011.01082.x. PMID: 21936875
Walsh SN, Hurt MA, Santa Cruz DJ
Am J Surg Pathol 2007 Dec;31(12):1897-901. doi: 10.1097/PAS.0b013e31806910c7. PMID: 18043046
Brownstein MH
J Cutan Pathol 1985 Jun-Aug;12(3-4):172-88. doi: 10.1111/j.1600-0560.1985.tb01620.x. PMID: 3160731
Anneroth A, Isacsson G
Acta Derm Venereol 1975;55(3):227-32. PMID: 50698

Therapy

Abramovits W, Abdelmalek N
J Am Acad Dermatol 2002 Feb;46(2 Suppl Case Reports):S4. doi: 10.1067/mjd.2002.104963. PMID: 11807455

Prognosis

Allon I, Buchner A
J Oral Pathol Med 2012 Mar;41(3):261-7. Epub 2011 Sep 21 doi: 10.1111/j.1600-0714.2011.01082.x. PMID: 21936875
Koç M, Kavala M, Kocatürk E, Mete O, Can B, Zindanci I, Aktas S
Dermatol Online J 2009 Feb 15;15(2):8. PMID: 19336025
Bergua P, Puig L, Fernández-Figueras MT, Baselga E, Alomar A
Pediatr Dermatol 2003 May-Jun;20(3):262-5. doi: 10.1046/j.1525-1470.2003.20316.x. PMID: 12787279
Duray PH, Merino MJ, Axiotis C
Int J Gynecol Pathol 1983;2(3):286-93. doi: 10.1097/00004347-198303000-00006. PMID: 6642851
Panja RK
J Cutan Pathol 1977 Sep;4(4):194-200. doi: 10.1111/j.1600-0560.1977.tb00908.x. PMID: 591661

Clinical prediction guides

Cohen PR
Am J Clin Dermatol 2011 Aug 1;12(4):217-31. doi: 10.2165/11586910-000000000-00000. PMID: 21668031
Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L
J Am Acad Dermatol 2002 Sep;47(3):423-8. doi: 10.1067/mjd.2002.122756. PMID: 12196754
Penneys NS
Br J Dermatol 1996 Oct;135(4):592-4. PMID: 8915152
Cooper PH
J Cutan Pathol 1989 Apr;16(2):81-4. doi: 10.1111/j.1600-0560.1989.tb00015.x. PMID: 2760291

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