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Acinetobacter infectious disease

MedGen UID:
1299
Concept ID:
C0001139
Disease or Syndrome
Synonyms: Acinetobacter Infection; Acinetobacter Infections; Infection, Acinetobacter; Infection, Mimae; Infections, Acinetobacter; Infections, Mimae; Mimae Infection; Mimae Infections
SNOMED CT: Acinetobacter infection (840588006); Infection caused by Acinetobacter (840588006)
 
HPO: HP:0032250
Monarch Initiative: MONDO:0006635

Definition

An infection by Acinetobacter baumannii, a Gram-negative bacillus that is aerobic, pleomorphic and non-motile. An opportunistic pathogen, A. baumannii has a high incidence among immunocompromised individuals, particularly those who have experienced a prolonged (over 90 d) hospital stay. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcinetobacter infectious disease

Professional guidelines

PubMed

Cantón R, Ruiz-Garbajosa P
Rev Esp Quimioter 2023 Nov;36 Suppl 1(Suppl 1):46-51. Epub 2023 Nov 24 doi: 10.37201/req/s01.11.2023. PMID: 37997871Free PMC Article
Sy CL, Chen PY, Cheng CW, Huang LJ, Wang CH, Chang TH, Chang YC, Chang CJ, Hii IM, Hsu YL, Hu YL, Hung PL, Kuo CY, Lin PC, Liu PY, Lo CL, Lo SH, Ting PJ, Tseng CF, Wang HW, Yang CH, Lee SS, Chen YS, Liu YC, Wang FD
J Microbiol Immunol Infect 2022 Jun;55(3):359-386. Epub 2022 Mar 16 doi: 10.1016/j.jmii.2022.02.001. PMID: 35370082
Paul M, Carrara E, Retamar P, Tängdén T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodríguez-Baño J
Clin Microbiol Infect 2022 Apr;28(4):521-547. Epub 2021 Dec 16 doi: 10.1016/j.cmi.2021.11.025. PMID: 34923128

Recent clinical studies

Etiology

Kaye KS, Shorr AF, Wunderink RG, Du B, Poirier GE, Rana K, Miller A, Lewis D, O'Donnell J, Chen L, Reinhart H, Srinivasan S, Isaacs R, Altarac D
Lancet Infect Dis 2023 Sep;23(9):1072-1084. Epub 2023 May 11 doi: 10.1016/S1473-3099(23)00184-6. PMID: 37182534
Sy CL, Chen PY, Cheng CW, Huang LJ, Wang CH, Chang TH, Chang YC, Chang CJ, Hii IM, Hsu YL, Hu YL, Hung PL, Kuo CY, Lin PC, Liu PY, Lo CL, Lo SH, Ting PJ, Tseng CF, Wang HW, Yang CH, Lee SS, Chen YS, Liu YC, Wang FD
J Microbiol Immunol Infect 2022 Jun;55(3):359-386. Epub 2022 Mar 16 doi: 10.1016/j.jmii.2022.02.001. PMID: 35370082
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Paul M, Carrara E, Retamar P, Tängdén T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodríguez-Baño J
Clin Microbiol Infect 2022 Apr;28(4):521-547. Epub 2021 Dec 16 doi: 10.1016/j.cmi.2021.11.025. PMID: 34923128
Bassetti M, Echols R, Matsunaga Y, Ariyasu M, Doi Y, Ferrer R, Lodise TP, Naas T, Niki Y, Paterson DL, Portsmouth S, Torre-Cisneros J, Toyoizumi K, Wunderink RG, Nagata TD
Lancet Infect Dis 2021 Feb;21(2):226-240. Epub 2020 Oct 12 doi: 10.1016/S1473-3099(20)30796-9. PMID: 33058795

Diagnosis

Russell NJ, Stöhr W, Plakkal N, Cook A, Berkley JA, Adhisivam B, Agarwal R, Ahmed NU, Balasegaram M, Ballot D, Bekker A, Berezin EN, Bilardi D, Boonkasidecha S, Carvalheiro CG, Chami N, Chaurasia S, Chiurchiu S, Colas VRF, Cousens S, Cressey TR, de Assis ACD, Dien TM, Ding Y, Dung NT, Dong H, Dramowski A, Ds M, Dudeja A, Feng J, Glupczynski Y, Goel S, Goossens H, Hao DTH, Khan MI, Huertas TM, Islam MS, Jarovsky D, Khavessian N, Khorana M, Kontou A, Kostyanev T, Laoyookhon P, Lochindarat S, Larsson M, Luca M, Malhotra-Kumar S, Mondal N, Mundhra N, Musoke P, Mussi-Pinhata MM, Nanavati R, Nakwa F, Nangia S, Nankunda J, Nardone A, Nyaoke B, Obiero CW, Owor M, Ping W, Preedisripipat K, Qazi S, Qi L, Ramdin T, Riddell A, Romani L, Roysuwan P, Saggers R, Roilides E, Saha SK, Sarafidis K, Tusubira V, Thomas R, Velaphi S, Vilken T, Wang X, Wang Y, Yang Y, Zunjie L, Ellis S, Bielicki JA, Walker AS, Heath PT, Sharland M
PLoS Med 2023 Jun;20(6):e1004179. Epub 2023 Jun 8 doi: 10.1371/journal.pmed.1004179. PMID: 37289666Free PMC Article
Pintado V, Ruiz-Garbajosa P, Aguilera-Alonso D, Baquero-Artigao F, Bou G, Cantón R, Grau S, Gutiérrez-Gutiérrez B, Larrosa N, Machuca I, Martínez Martínez L, Montero MM, Morte-Romea E, Oliver A, Paño-Pardo JR, Sorlí L
Enferm Infecc Microbiol Clin (Engl Ed) 2023 Jun-Jul;41(6):360-370. Epub 2022 Dec 13 doi: 10.1016/j.eimce.2022.06.014. PMID: 36522272
Fu P, Xu H, Jing C, Deng J, Wang H, Hua C, Chen Y, Chen X, Zhang T, Zhang H, Chen Y, Yang J, Lin A, Wang S, Cao Q, Wang X, Deng H, Cao S, Hao J, Gao W, Huang Y, Yu H, Wang C
Microbiol Spectr 2021 Dec 22;9(3):e0028321. Epub 2021 Nov 3 doi: 10.1128/Spectrum.00283-21. PMID: 34730410Free PMC Article
Alonso-Aguilar NM, Juarez-Enriquez SR, Castro-Escarpulli G, Rivera G, Bocanegra-Garcia V, Guo X, Luna-Herrera J, Aguilera-Arreola MG
Clin Lab 2017 Feb 1;63(2):207-218. doi: 10.7754/Clin.Lab.2016.151119. PMID: 28182358
Branski LK, Al-Mousawi A, Rivero H, Jeschke MG, Sanford AP, Herndon DN
Surg Infect (Larchmt) 2009 Oct;10(5):389-97. doi: 10.1089/sur.2009.024. PMID: 19810827Free PMC Article

Therapy

Cantón R, Ruiz-Garbajosa P
Rev Esp Quimioter 2023 Nov;36 Suppl 1(Suppl 1):46-51. Epub 2023 Nov 24 doi: 10.37201/req/s01.11.2023. PMID: 37997871Free PMC Article
Kaye KS, Shorr AF, Wunderink RG, Du B, Poirier GE, Rana K, Miller A, Lewis D, O'Donnell J, Chen L, Reinhart H, Srinivasan S, Isaacs R, Altarac D
Lancet Infect Dis 2023 Sep;23(9):1072-1084. Epub 2023 May 11 doi: 10.1016/S1473-3099(23)00184-6. PMID: 37182534
Sy CL, Chen PY, Cheng CW, Huang LJ, Wang CH, Chang TH, Chang YC, Chang CJ, Hii IM, Hsu YL, Hu YL, Hung PL, Kuo CY, Lin PC, Liu PY, Lo CL, Lo SH, Ting PJ, Tseng CF, Wang HW, Yang CH, Lee SS, Chen YS, Liu YC, Wang FD
J Microbiol Immunol Infect 2022 Jun;55(3):359-386. Epub 2022 Mar 16 doi: 10.1016/j.jmii.2022.02.001. PMID: 35370082
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Paul M, Carrara E, Retamar P, Tängdén T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodríguez-Baño J
Clin Microbiol Infect 2022 Apr;28(4):521-547. Epub 2021 Dec 16 doi: 10.1016/j.cmi.2021.11.025. PMID: 34923128

Prognosis

Bassat Q, Blau DM, Ogbuanu IU, Samura S, Kaluma E, Bassey IA, Sow S, Keita AM, Tapia MD, Mehta A, Kotloff KL, Rahman A, Islam KM, Alam M, El Arifeen S, Gurley ES, Baillie V, Mutevedzi P, Mahtab S, Thwala BN, Tippett Barr BA, Onyango D, Akelo V, Rogena E, Onyango P, Omore R, Mandomando I, Ajanovic S, Varo R, Sitoe A, Duran-Frigola M, Assefa N, Scott JAG, Madrid L, Tesfaye T, Dessie Y, Madewell ZJ, Breiman RF, Whitney CG, Madhi SA; Child Health and Mortality Prevention Surveillance (CHAMPS) Network
JAMA Netw Open 2023 Jul 3;6(7):e2322494. doi: 10.1001/jamanetworkopen.2023.22494. PMID: 37494044Free PMC Article
European Antimicrobial Resistance Collaborators
Lancet Public Health 2022 Nov;7(11):e897-e913. Epub 2022 Oct 14 doi: 10.1016/S2468-2667(22)00225-0. PMID: 36244350Free PMC Article
Mende K, Akers KS, Tyner SD, Bennett JW, Simons MP, Blyth DM, Li P, Stewart L, Tribble DR
Mil Med 2022 May 4;187(Suppl 2):42-51. doi: 10.1093/milmed/usab131. PMID: 35512375Free PMC Article
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Kadri SS, Adjemian J, Lai YL, Spaulding AB, Ricotta E, Prevots DR, Palmore TN, Rhee C, Klompas M, Dekker JP, Powers JH 3rd, Suffredini AF, Hooper DC, Fridkin S, Danner RL; National Institutes of Health Antimicrobial Resistance Outcomes Research Initiative (NIH–ARORI)
Clin Infect Dis 2018 Nov 28;67(12):1803-1814. doi: 10.1093/cid/ciy378. PMID: 30052813Free PMC Article

Clinical prediction guides

Wang M, Ge L, Chen L, Komarow L, Hanson B, Reyes J, Cober E, Alenazi T, Zong Z, Xie Q, Liu Z, Li L, Yu Y, Gao H, Kanj SS, Figueroa J, Herc E, Cordova E, Weston G, Ananth Tambyah P, Garcia-Diaz J, Kaye KS, Dhar S, Munita JM, Salata RA, Vilchez S, Stryjewski ME, Villegas Botero MV, Iovleva A, Evans SR, Baum K, Hill C, Kreiswirth BN, Patel R, Paterson DL, Arias CA, Bonomo RA, Chambers HF, Fowler VG Jr, Satlin MJ, van Duin D, Doi Y; Multi-Drug Resistant Organism Network Investigators
Clin Infect Dis 2024 Feb 17;78(2):248-258. doi: 10.1093/cid/ciad556. PMID: 37738153Free PMC Article
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Paul M, Carrara E, Retamar P, Tängdén T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodríguez-Baño J
Clin Microbiol Infect 2022 Apr;28(4):521-547. Epub 2021 Dec 16 doi: 10.1016/j.cmi.2021.11.025. PMID: 34923128
Wunderink RG, Matsunaga Y, Ariyasu M, Clevenbergh P, Echols R, Kaye KS, Kollef M, Menon A, Pogue JM, Shorr AF, Timsit JF, Zeitlinger M, Nagata TD
Lancet Infect Dis 2021 Feb;21(2):213-225. Epub 2020 Oct 12 doi: 10.1016/S1473-3099(20)30731-3. PMID: 33058798
Tacconelli E, Carrara E, Savoldi A, Harbarth S, Mendelson M, Monnet DL, Pulcini C, Kahlmeter G, Kluytmans J, Carmeli Y, Ouellette M, Outterson K, Patel J, Cavaleri M, Cox EM, Houchens CR, Grayson ML, Hansen P, Singh N, Theuretzbacher U, Magrini N; WHO Pathogens Priority List Working Group
Lancet Infect Dis 2018 Mar;18(3):318-327. Epub 2017 Dec 21 doi: 10.1016/S1473-3099(17)30753-3. PMID: 29276051

Recent systematic reviews

Allel K, Stone J, Undurraga EA, Day L, Moore CE, Lin L, Furuya-Kanamori L, Yakob L
PLoS Med 2023 Jun;20(6):e1004199. Epub 2023 Jun 22 doi: 10.1371/journal.pmed.1004199. PMID: 37347726Free PMC Article
Antimicrobial Resistance Collaborators
Lancet 2022 Feb 12;399(10325):629-655. Epub 2022 Jan 19 doi: 10.1016/S0140-6736(21)02724-0. PMID: 35065702Free PMC Article
Ayobami O, Brinkwirth S, Eckmanns T, Markwart R
Emerg Microbes Infect 2022 Dec;11(1):443-451. doi: 10.1080/22221751.2022.2030196. PMID: 35034585Free PMC Article
Paul M, Carrara E, Retamar P, Tängdén T, Bitterman R, Bonomo RA, de Waele J, Daikos GL, Akova M, Harbarth S, Pulcini C, Garnacho-Montero J, Seme K, Tumbarello M, Lindemann PC, Gandra S, Yu Y, Bassetti M, Mouton JW, Tacconelli E, Rodríguez-Baño J
Clin Microbiol Infect 2022 Apr;28(4):521-547. Epub 2021 Dec 16 doi: 10.1016/j.cmi.2021.11.025. PMID: 34923128
Tacconelli E, Cataldo MA, Dancer SJ, De Angelis G, Falcone M, Frank U, Kahlmeter G, Pan A, Petrosillo N, Rodríguez-Baño J, Singh N, Venditti M, Yokoe DS, Cookson B; European Society of Clinical Microbiology
Clin Microbiol Infect 2014 Jan;20 Suppl 1:1-55. doi: 10.1111/1469-0691.12427. PMID: 24329732

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