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    ST18 ST18 C2H2C-type zinc finger transcription factor [ Homo sapiens (human) ]

    Gene ID: 9705, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ST18provided by HGNC
    Official Full Name
    ST18 C2H2C-type zinc finger transcription factorprovided by HGNC
    Primary source
    HGNC:HGNC:18695
    See related
    Ensembl:ENSG00000147488 MIM:617155; AllianceGenome:HGNC:18695
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NZF3; NZF-3; ZNF387; ZC2H2C3; ZC2HC10
    Summary
    Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in brain (RPKM 3.7), stomach (RPKM 0.7) and 3 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ST18 in Genome Data Viewer
    Location:
    8q11.23
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (52110838..52409879, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (52486561..52785956, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (53023398..53322439, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27339 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27340 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27341 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:52837590-52838789 Neighboring gene PCMTD1 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19187 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27342 Neighboring gene uncharacterized LOC124901944 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27343 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:52959497-52959996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:53013330-53014276 Neighboring gene uncharacterized LOC124901945 Neighboring gene uncharacterized LOC101929341 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:53125987-53126195 Neighboring gene VISTA enhancer hs698 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_103338 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27344 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27345 Neighboring gene MPRA-validated peak7016 silencer Neighboring gene ribosomal protein L34 pseudogene 17 Neighboring gene ST18-FAM150A intergenic CAGE-defined low expression enhancer Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:53458378-53459577 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:53476246-53477222 Neighboring gene MPRA-validated peak7018 silencer Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr8:53512288-53512788 Neighboring gene ALK and LTK ligand 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:53541841-53542555 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:53566637-53567138 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:53567139-53567638 Neighboring gene RB1 inducible coiled-coil 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19188 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19189 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19190 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19191

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Population-specific association between a polymorphic variant in ST18, encoding a pro-apoptotic molecule, and pemphigus vulgaris. Sarig O, et al. J Invest Dermatol, 2012 Jul. PMID 22437316
    2. ST18 affects cell-cell adhesion in pemphigus vulgaris in a tumour necrosis factor-α-dependent fashion. Assaf S, et al. Br J Dermatol, 2021 Jun. PMID 33205400
    3. ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation. Radeva MY, et al. Front Immunol, 2019. PMID 31057535, Free PMC Article
    4. High-resolution melting analysis to screen the ST18 gene functional risk variant for pemphigus vulgaris: The occasion to open a debate on its usefulness in clinical setting. De Bonis M, et al. Exp Mol Pathol, 2019 Jun. PMID 30926339
    5. Lack of association between the single nucleotide polymorphism of ST18 and pemphigus in Chinese population. Yue Z, et al. J Dermatol, 2014 Apr. PMID 24612320

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. a Chinese population shows no remarkable association with the SNP rs2304365 in the region of ST18 and pemphigus, which suggests the relationship of ST18 and pemphigus may act in a population-specific manner
      Title: Lack of association between the single nucleotide polymorphism of ST18 and pemphigus in Chinese population.
    2. Up-regulation of ST18 in pemphigus vulgaris drives a self-amplifying p53-dependent pathomechanism resulting in decreased desmoglein 3 expression.
      Title: Up-regulation of ST18 in pemphigus vulgaris drives a self-amplifying p53-dependent pathomechanism resulting in decreased desmoglein 3 expression.
    3. Measurable Residual Disease Monitoring of SPAG6, ST18, PRAME, and XAGE1A Expression in Peripheral Blood May Detect Imminent Relapse in Childhood Acute Myeloid Leukemia.
      Title: Measurable Residual Disease Monitoring of SPAG6, ST18, PRAME, and XAGE1A Expression in Peripheral Blood May Detect Imminent Relapse in Childhood Acute Myeloid Leukemia.
    4. Genome-wide association study identifies susceptibility loci of brain atrophy to NFIA and ST18 in Alzheimer's disease.
      Title: Genome-wide association study identifies susceptibility loci of brain atrophy to NFIA and ST18 in Alzheimer's disease.
    5. ST18 affects cell-cell adhesion in pemphigus vulgaris in a tumour necrosis factor-alpha-dependent fashion.
      Title: ST18 affects cell-cell adhesion in pemphigus vulgaris in a tumour necrosis factor-α-dependent fashion.
    6. ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation.
      Title: ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation.
    7. The suppression of tumorigenicity 18 protein ST18 (ST18) -497-65050T>C polymorphisms (rs17315309) exhibit a very strong association in the pathogenesis of Pemphigus Vulgaris (PV) and could represent a new potential molecular target for the treatment of disease.
      Title: High-resolution melting analysis to screen the ST18 gene functional risk variant for pemphigus vulgaris: The occasion to open a debate on its usefulness in clinical setting.
    8. allele A in rs2304365 of ST18 may have a role in pemphigus in Iranian patients
      Title: The association between ST18 gene polymorphism and severe pemphigus disease among Iranian population.
    9. In this study, 2 of 8 (primary angle-closure glaucoma) PACG-associated loci were associated significantly with PACS status, the earliest stage in the angle-closure glaucoma disease course. The association of these PACG loci with PACS status suggests that these loci may confer susceptibility to a narrow angle configuration.
      Title: Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease.
    10. the present findings indicate that ST18 may play a direct role in Pemphigus vulgaris (PV) and consequently represents a potential target for the treatment of this disease.
      Title: Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene.
    Submit: New GeneRIF Correction See all GeneRIFs (17)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
    EBI GWAS Catalog

    Variation

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    See Variation Viewer (GRCh37.p13)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0535

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in interleukin-1-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in interleukin-6-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of cysteine-type endopeptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tumor necrosis factor-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-DNA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppression of tumorigenicity 18 protein
    Names
    ST18, C2H2C-type zinc finger
    neural zinc finger transcription factor 3
    suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
    suppression of tumorigenicity 18, zinc finger
    zinc finger protein 387

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001352826.2 → NP_001339755.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    2. NM_001352827.2 → NP_001339756.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    3. NM_001352828.2 → NP_001339757.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000514122.1, ENST00000699087.1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    4. NM_001352829.2 → NP_001339758.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    5. NM_001352830.2 → NP_001339759.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    6. NM_001352831.2 → NP_001339760.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000508476.1, ENST00000693301.1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    7. NM_001352832.2 → NP_001339761.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    8. NM_001352833.2 → NP_001339762.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    9. NM_001352834.2 → NP_001339763.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    10. NM_001352835.2 → NP_001339764.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    11. NM_001352836.2 → NP_001339765.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    12. NM_001352837.2 → NP_001339766.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000509475.1, ENST00000689386.1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    13. NM_001352838.2 → NP_001339767.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    14. NM_001352839.2 → NP_001339768.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    15. NM_001352840.2 → NP_001339769.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    16. NM_001352841.2 → NP_001339770.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (17) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    17. NM_001352842.2 → NP_001339771.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (18) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    18. NM_001352843.2 → NP_001339772.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (19) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    19. NM_001352844.2 → NP_001339773.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (20) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    20. NM_001352845.2 → NP_001339774.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (21) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    21. NM_001352846.2 → NP_001339775.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (22) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    22. NM_001352847.2 → NP_001339776.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (23) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    23. NM_001352848.2 → NP_001339777.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (24) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    24. NM_001352849.2 → NP_001339778.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (25) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    25. NM_001352850.2 → NP_001339779.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (26) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    26. NM_001352851.2 → NP_001339780.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (27) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    27. NM_001352852.2 → NP_001339781.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (28) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    28. NM_001352853.2 → NP_001339782.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (29) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    29. NM_001352854.2 → NP_001339783.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (30) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    30. NM_001352855.2 → NP_001339784.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (31) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    31. NM_001352856.2 → NP_001339785.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (32) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    32. NM_001352857.2 → NP_001339786.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (33) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    33. NM_001352858.2 → NP_001339787.1  suppression of tumorigenicity 18 protein isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (43) encodes isoform c. Variants 43-45 all encode isoform c.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:738 → 766
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:450 → 686
      MYT1; Myelin transcription factor 1
      cl25732
      Location:892 → 963
      SMC_N; RecF/RecN/SMC N terminal domain

    34. NM_001352859.2 → NP_001339788.1  suppression of tumorigenicity 18 protein isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (44) encodes isoform c. Variants 43-45 all encode isoform c.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:738 → 766
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:450 → 686
      MYT1; Myelin transcription factor 1
      cl25732
      Location:892 → 963
      SMC_N; RecF/RecN/SMC N terminal domain

    35. NM_001352860.2 → NP_001339789.1  suppression of tumorigenicity 18 protein isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (45) encodes isoform c. Variants 43-45 all encode isoform c.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:738 → 766
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:450 → 686
      MYT1; Myelin transcription factor 1
      cl25732
      Location:892 → 963
      SMC_N; RecF/RecN/SMC N terminal domain

    36. NM_001352861.2 → NP_001339790.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (34) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    37. NM_001352862.2 → NP_001339791.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (35) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    38. NM_001352863.2 → NP_001339792.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (36) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    39. NM_001352864.2 → NP_001339793.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (37) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    40. NM_001352865.2 → NP_001339794.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (38) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    41. NM_001352866.2 → NP_001339795.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (39) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    42. NM_001352867.2 → NP_001339796.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (40) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    43. NM_001352868.2 → NP_001339797.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (41) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    44. NM_001352869.2 → NP_001339798.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (42) encodes isoform b. Variants 46-51 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732 → 760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444 → 680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886 → 957
      SMC_N; RecF/RecN/SMC N terminal domain

    45. NM_001352870.2 → NP_001339799.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (46) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:685 → 713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839 → 910
      SMC_N; RecF/RecN/SMC N terminal domain

    46. NM_001352871.2 → NP_001339800.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (47) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:685 → 713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839 → 910
      SMC_N; RecF/RecN/SMC N terminal domain

    47. NM_001352872.2 → NP_001339801.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (48) encodes isoform d. Variants 34-42 all encode isoform d.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:685 → 713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839 → 910
      SMC_N; RecF/RecN/SMC N terminal domain

    48. NM_001352873.2 → NP_001339802.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (49) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:685 → 713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839 → 910
      SMC_N; RecF/RecN/SMC N terminal domain

    49. NM_001352874.2 → NP_001339803.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (50) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:685 → 713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839 → 910
      SMC_N; RecF/RecN/SMC N terminal domain

    50. NM_001352875.2 → NP_001339804.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (51) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:685 → 713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839 → 910
      SMC_N; RecF/RecN/SMC N terminal domain

    51. NM_001352876.2 → NP_001339805.1  suppression of tumorigenicity 18 protein isoform f

      Status: VALIDATED

      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:421 → 449
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:215 → 369
      MYT1; Myelin transcription factor 1
      cl25732
      Location:575 → 646
      SMC_N; RecF/RecN/SMC N terminal domain

    52. NM_001352877.2 → NP_001339806.1  suppression of tumorigenicity 18 protein isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (52) encodes isoform e. Variants 52 and 53 both encode isoform e.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:414 → 442
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:126 → 362
      MYT1; Myelin transcription factor 1
      cl25732
      Location:568 → 639
      SMC_N; RecF/RecN/SMC N terminal domain

    53. NM_001352878.2 → NP_001339807.1  suppression of tumorigenicity 18 protein isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (53) encodes isoform e. Variants 52 and 53 both encode isoform e.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:414 → 442
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:126 → 362
      MYT1; Myelin transcription factor 1
      cl25732
      Location:568 → 639
      SMC_N; RecF/RecN/SMC N terminal domain

    54. NM_001352879.1 → NP_001339808.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (55) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC103831

    55. NM_001352880.1 → NP_001339809.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (56) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC103831

    56. NM_001352881.1 → NP_001339810.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (57) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC021915, AC103831

    57. NM_001352882.1 → NP_001339811.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (58) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC103831

    58. NM_001352883.2 → NP_001339812.1  suppression of tumorigenicity 18 protein isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (59) encodes isoform h. Variants 59 and 60 both encode isoform h.
      Source sequence(s)
      AC103831
      Related
      ENST00000522102.5

    59. NM_001352884.2 → NP_001339813.1  suppression of tumorigenicity 18 protein isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (60) encodes isoform h. Variants 59 and 60 both encode isoform h.
      Source sequence(s)
      AC103831

    60. NM_014682.3 → NP_055497.1  suppression of tumorigenicity 18 protein isoform a

      See identical proteins and their annotated locations for NP_055497.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AB011107, BC117147, BQ639545, DA288225
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000276480.7, ENST00000276480.11
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    RNA

    1. NR_148195.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC021915, AC103831

    2. NR_148196.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC021915

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      52110838..52409879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047422485.1 → XP_047278441.1  suppression of tumorigenicity 18 protein isoform X2

    2. XM_047422486.1 → XP_047278442.1  suppression of tumorigenicity 18 protein isoform X2

    3. XM_047422487.1 → XP_047278443.1  suppression of tumorigenicity 18 protein isoform X2

    4. XM_024447349.2 → XP_024303117.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    5. XM_047422484.1 → XP_047278440.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1

    6. XM_017014058.2 → XP_016869547.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767 → 795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479 → 715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921 → 992
      SMC_N; RecF/RecN/SMC N terminal domain

    7. XM_024447350.2 → XP_024303118.1  suppression of tumorigenicity 18 protein isoform X3

      Conserved Domains (3) summary
      pfam01530
      Location:414 → 442
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:126 → 362
      MYT1; Myelin transcription factor 1
      cl25732
      Location:568 → 639
      SMC_N; RecF/RecN/SMC N terminal domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      52486561..52785956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054361604.1 → XP_054217579.1  suppression of tumorigenicity 18 protein isoform X2

    2. XM_054361605.1 → XP_054217580.1  suppression of tumorigenicity 18 protein isoform X2

    3. XM_054361606.1 → XP_054217581.1  suppression of tumorigenicity 18 protein isoform X2

    4. XM_054361602.1 → XP_054217577.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1

    5. XM_054361601.1 → XP_054217576.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1

    6. XM_054361603.1 → XP_054217578.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1

    7. XM_054361607.1 → XP_054217582.1  suppression of tumorigenicity 18 protein isoform X3

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O60284.1 GenPept UniProtKB/Swiss-Prot:O60284

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