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| Status |
Public on Sep 19, 2012 |
| Title |
Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large b-cell lymphoma and predict clinical outcome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression profiling was carried out for RNA extracted from Formalin-fixed, paraffin embedded (FFPE) biopsies for 172 patients with diffuse large b-cell lymphoma (DLBCL) using the Illumina DASL platform. Classification into GCB, ABC or Type-III subtypes was carried out revealing a significant relationship between subtype and survival.
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| |
|
| Overall design |
A retrospective study of 172 patients, 140 treated with R-CHOP, 32 not treated with curative intent
|
| |
|
| Contributor(s) |
Barrans SL, Care MA |
| Citation(s) |
22970711, 24875472 |
| |
| Submission date |
Oct 12, 2011 |
| Last update date |
May 14, 2015 |
| Contact name |
Matthew Anthony Care |
| E-mail(s) |
matthew.care@york.ac.uk
|
| Organization name |
The University of York
|
| Department |
Department of Biology
|
| Lab |
Bioscience Technology Facility, Data Science Hub
|
| Street address |
Wentworth Way
|
| City |
York |
| State/province |
North Yorkshire |
| ZIP/Postal code |
YO10 5DD |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL8432 |
Illumina HumanRef-8 WG-DASL v3.0 |
|
| Samples (249)
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| Relations |
| BioProject |
PRJNA146477 |
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