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| Status |
Public on Jan 31, 2018 |
| Title |
The RFX transcription factor gene, daf-19, has dual funcitons in ciliated and non-ciliated neurons |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
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| Summary |
Cilia are required for many sensory and motility related functions and are involved in growing number of genetic disorders termed ciliopathies. DAF-19, RFX type transcription factor controls expression of many cilia structure and function related genes. To this end, transcriptional profiling of daf-19 mutants (which do not form cilia) and wild-type animals was performed using selectively staged larval stages where cilia mature and maintained, structurally as well as functionally.
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| Overall design |
We used microarray based expression analysis to detail expression control exerted by DAF-19 at various stages of life cycle
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| Contributor(s) |
De Stasio E, Phirke P, Swoboda P |
| Citation(s) |
29301909 |
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| Submission date |
Mar 10, 2017 |
| Last update date |
Jul 08, 2019 |
| Contact name |
Prasad Phirke |
| Organization name |
Karolinska Institutet
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| Street address |
Hälsovägen 7
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| City |
Huddinge |
| ZIP/Postal code |
14183 |
| Country |
Sweden |
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| Platforms (1) |
| GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
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| Samples (14)
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| GSM2532762 |
Stage L1, DAF(-), Biological rep 4 |
| GSM2532763 |
Stage L1, DAF(+), Biological rep 1 |
| GSM2532764 |
Stage L1, DAF(+), Biological rep 2 |
| GSM2532765 |
Stage L1, DAF(+), Biological rep 3 |
| GSM2532766 |
Stage L1, DAF(+), Biological rep 4 |
| GSM2532767 |
Young Adult, DAF(-), Biological rep 1 |
| GSM2532768 |
Young Adult, DAF(-), Biological rep 2 |
| GSM2532769 |
Young Adult, DAF(-), Biological rep 3 |
| GSM2532770 |
Young Adult, DAF(+), Biological rep 1 |
| GSM2532771 |
Young Adult, DAF(+), Biological rep 2 |
| GSM2532772 |
Young Adult, DAF(+), Biological rep 3 |
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| Relations |
| BioProject |
PRJNA378754 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE96068_RAW.tar |
29.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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