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| Status |
Public on Sep 25, 2017 |
| Title |
Phospholipase Cγ pathway-dependent mTOR signaling controls IL-7-mediated early B cell development |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We examined the global gene expression profile of PLCγ1/PLCγ2 double-deficient CLPsand B cell progenitors by RNA-seq analysis.
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| |
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| Overall design |
CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+) were sorted from PLCγ1-/-PLCγ2-/- and control mice, and subjected to RNA-seq analysis. 3 repricates of each population from each genotype.
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| |
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| Contributor(s) |
Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D |
| Citation(s) |
29133930 |
| |
| Submission date |
Oct 31, 2016 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Geoffrey Neale |
| E-mail(s) |
geoffrey.neale@stjude.org
|
| Organization name |
St Jude Childrens Research Hospital
|
| Department |
Hartwell Center
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA351862 |
| SRA |
SRP092346 |
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