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Series GSE89352 Query DataSets for GSE89352
Status Public on Sep 25, 2017
Title Phospholipase Cγ pathway-dependent mTOR signaling controls IL-7-mediated early B cell development
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We examined the global gene expression profile of PLCγ1/PLCγ2 double-deficient CLPsand B cell progenitors by RNA-seq analysis.
Overall design CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+) were sorted from PLCγ1-/-PLCγ2-/- and control mice, and subjected to RNA-seq analysis. 3 repricates of each population from each genotype.
Contributor(s) Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D
Citation(s) 29133930
Submission date Oct 31, 2016
Last update date Mar 25, 2019
Contact name Geoffrey Neale
Organization name St Jude Childrens Research Hospital
Department Hartwell Center
Street address 262 Danny Thomas Place
City Memphis
State/province TN
ZIP/Postal code 38105
Country USA
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (24)
GSM2366977 G1810_WT_CLP
GSM2366978 G1811_G1KO_CLP
GSM2366979 G1809_G2KO_CLP
BioProject PRJNA351862
SRA SRP092346

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE89352_RAW.tar 3.0 Mb (http)(custom) TAR (of TXT)
Raw data are available in SRA
Processed data provided as supplementary file

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