|
| Status |
Public on May 25, 2016 |
| Title |
Premalignant lesions of the bronchial epithelium |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of hyperplastic, metaplastic, and dysplastic lesions of the bronchus in comparison with normal bronchial epithelium. The aim was to identify transcripts and cell signalling pathways associated with the development of isolated premalignant lesions and/or lesions combined with each other in the same bronchial epithelium.
|
| |
|
| Overall design |
Basal cell hyperplasia (n=4), squamous metaplasia (n=4), and dysplasia (n=1) vs. normal bronchial epithelial cells (n=1)
|
| |
|
| Contributor(s) |
Denisov EV, Gerashchenko TS, Yakushina VD, Skryabin NA, Sleptsov AA, Tashireva LA, Pankova OV, Perelmuter VM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 24, 2016 |
| Last update date |
Jan 09, 2018 |
| Contact name |
Aleksei A Sleptcov |
| E-mail(s) |
alexei.sleptcov@medgenetics.ru
|
| Phone |
+79131137848
|
| Organization name |
Research Institute of Medical Genetics
|
| Lab |
Population Genetics
|
| Street address |
10 Naberejnaya Ushaiki
|
| City |
Tomsk |
| State/province |
Tomskaya oblasty |
| ZIP/Postal code |
634050 |
| Country |
Russia |
| |
|
| Platforms (1) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
| Samples (10)
|
| GSM2176319 |
isolated basal cell hyperplasia_VO |
| GSM2176320 |
isolated basal cell hyperplasia_DI |
| GSM2176321 |
basal cell hyperplasia combined with squamous metaplasia_SR |
| GSM2176323 |
basal cell hyperplasia combined with squamous metaplasia_SM |
| GSM2176324 |
isolated squamous metaplasia_LI |
| GSM2176325 |
squamous metaplasia combined with basal cell hyperplasia_SR |
| GSM2176327 |
squamous metaplasia combined with basal cell hyperplasia_SM |
| GSM2176329 |
squamous metaplasia combined with dysplasia_GV |
| GSM2176332 |
dysplasia combined with squamous metaplasia_GV |
| GSM2176334 |
normal bronchial epithelium_GE |
|
| Relations |
| BioProject |
PRJNA322627 |
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