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Series GSE72396 Query DataSets for GSE72396
Status Public on Aug 27, 2015
Title Expression data from HaCaT cells stimulated by IL-22
Platform organisms Homo sapiens; synthetic construct
Sample organism Homo sapiens
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary Psoriasis is an inflammatory skin disease and the exact pathogenesis has not been fully illuminated yet. It has been demonstrated that interleukin-22 (IL-22) plays a significant role in the pathogenesis of psoriasis.
Our study aimed to explore the role of IL-22 and its target miRNAs in pathogenesis of psoriasis.
 
Overall design Differentially expressed miRNAs and mRNAs in HaCaT cells with IL-22 stimulation were analysed through miRNA and mRNA microarrays. qRT-PCR assay was conducted to validate microarrays results.
 
Contributor(s) Sun Q, Jiang M
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Aug 26, 2015
Last update date Mar 15, 2019
Contact name Meng Jiang
E-mail(s) 1037447134@qq.com
Phone 15066142801
Organization name Qilu hospital
Street address lixia street
City Jinan
State/province Shandong
ZIP/Postal code 250012
Country China
 
Platforms (2)
GPL16686 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version]
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (8)
GSM1861816 HaCaT-1 [miRNA]
GSM1861817 HaCaT-2 [miRNA]
GSM1861818 IL-22-1 [miRNA]
Relations
BioProject PRJNA293946

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE72396_RAW.tar 33.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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