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| Status |
Public on Sep 11, 2015 |
| Title |
Human embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest |
| Organism |
Homo sapiens |
| Experiment type |
SNP genotyping by SNP array
Genome variation profiling by SNP array
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| Summary |
Nuclear abnormalities are commonly found in human IVF embryos and are associated with DNA damage, aneuploidy, and decreased developmental potential.
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| Overall design |
Immunohistochemical, microscopic, and cytogenetic analysis of human IVF embryos at different developmental stages and morphologic grades.
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| Contributor(s) |
Kort DH, Chia G, Treff NR, Tanaka AJ, Vensand LB, Micucci S, Prosser R, Sauer MV, Egli D |
| Citation(s) |
26621855 |
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| Submission date |
Aug 18, 2015 |
| Last update date |
May 17, 2017 |
| Contact name |
Dieter Egli |
| Organization name |
Columbia University
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| Street address |
116th St & Broadway
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10027 |
| Country |
USA |
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| Platforms (1) |
| GPL3718 |
[Mapping250K_Nsp] Affymetrix Mapping 250K Nsp SNP Array |
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| Samples (72)
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| Relations |
| BioProject |
PRJNA295393 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE72150_RAW.tar |
2.0 Gb |
(http)(custom) |
TAR (of CEL, CHP, TXT) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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