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Series GSE64415 Query DataSets for GSE64415
Status Public on May 21, 2015
Title Gene expression data from ependymal tumor samples
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Ependymal tumors across age groups have been classified and graded solely by histopathology. It is, however, commonly accepted that this classification scheme has limited clinical utility based on its lack of reproducibility in predicting patient outcome. We aimed at establishing a reliable molecular classification using DNA methylation fingerprints and gene expression data of the tumors on a large cohort of 500 tumors. Nine robust molecular subgroups, three in each anatomic compartment of the central nervous system (CNS), were identified.
Overall design Total RNA from 209 ependymal tumor samples were hybridised to the Affymetrix HG U133 Plus 2.0 microarrays.
Contributor(s) Pajtler K, Witt H, Sill M, Korshunov A, Kool M, Pfister SM
Citation(s) 25965575, 29909548, 31043743
Submission date Dec 22, 2014
Last update date Jul 30, 2019
Contact name Marcel Kool
Organization name German Cancer Research Center DKFZ
Department Pediatric Neurooncology
Street address Im Neuenheimer Feld 280
City Heidelberg
ZIP/Postal code 69120
Country Germany
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (209)
GSM1570843 1ep1
GSM1570844 1ep11
GSM1570845 1ep12
BioProject PRJNA270979

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64415_RAW.tar 935.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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