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Series GSE62030 Query DataSets for GSE62030
Status Public on Oct 08, 2015
Title Integrated ordination of miRNA and mRNA expression profiles [miRNA]
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Several studies have shown that negative and positive miRNA-mRNA correlations are symmetrically distributed. While negative correlations are consistent with a faster degradation of miRNA targets, the presence of positive correlations suggests bidirectional interactions between the two classes of molecules. However, a comprehensive study of miRNA and mRNA correlations is lacking. A homogeneous map of miRNA and mRNA relationships was obtained by multidimensional scaling (MDS) applied to a single matrix including both heterologous (miRNA-mRNA) and homologous (miRNA-miRNA and mRNA-mRNA) correlations.
 
Overall design Liver samples were obtained from 4 patients with HBV-associated acute liver failure (ALF), 10 liver donors and 7 subjects who underwent hepatic resection for liver angioma.
 
Contributor(s) Diaz G, Zamboni F, Tice A, Farci P
Citation(s) 26459852
Submission date Oct 03, 2014
Last update date May 02, 2017
Contact name Giacomo Diaz
E-mail(s) gdiaz@unica.it
Organization name University of Cagliari
Department Dept Biomedical Sciences
Street address Via Porcell 4
City Cagliari
ZIP/Postal code 09124
Country Italy
 
Platforms (1)
GPL14613 [miRNA-2] Affymetrix Multispecies miRNA-2 Array
Samples (30)
GSM1518722 patient 219 with ALF - whole liver tissue miRNA - miRNA-ALF-219-1
GSM1518723 patient 219 with ALF - whole liver tissue miRNA - miRNA-ALF-219-2
GSM1518724 patient 219 with ALF - whole liver tissue miRNA - miRNA-ALF-219-3
This SubSeries is part of SuperSeries:
GSE62037 Integrated ordination of miRNA and mRNA expression profiles
Relations
BioProject PRJNA263012

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE62030_RAW.tar 19.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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