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Series GSE60745 Query DataSets for GSE60745
Status Public on Jul 23, 2015
Title 14-3-3ζ controls adipocyte progenitor cell cycle and differentiation via Gli3-dependent p27Kip expression
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary 14-3-3 proteins facilitate cytoplasmic-nuclear shuttling of transcription factors.Adipocyte differentiation requires the function of critical transcription factors to drive the development of a mature adipocyte. The aim of the study was to investigate if 14-3-3ζ is required for the adipogenic transcriptional program.
Overall design Examination of the transcriptome in siCon- and si14-3-3ζ-transfected 3T3-L1 cells undergoing differentiation at t=0, 24, and 48 hours.
Contributor(s) Lim GE, Johnson JD
Citation(s) 26220403
Submission date Aug 26, 2014
Last update date May 15, 2019
Contact name Gareth Lim
Organization name CRCHUM
Street address R08.482- 900 rue St Denis
City Montreal
State/province Quebec
ZIP/Postal code H2X 0A9
Country Canada
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (24)
GSM1486600 C1-siCon-t=0-rep1
GSM1486601 C2-siCon-t=241rep1
GSM1486602 C3-siCon-t=48-rep1
BioProject PRJNA259415
SRA SRP045772

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Supplementary file Size Download File type/resource
GSE60745_Lim_et_al.-si14-3-3z_adipogenic_transcriptome.xls.gz 2.0 Mb (ftp)(http) XLS
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