 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Dec 01, 2014 |
| Title |
TOX3 is Expressed in Mammary ER Positive Epithelial Cells and Regulates a Subset of ER Target Genes in a Ligand-Independent Manner in Luminal Breast Cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To assess how the TOX3 nuclear protein can modulate gene expression in luminal epithelial cells, MCF7 cells were transfected with a TOX3 expression vector or vector control. In both instances, GFP was coexpressed, allowing isolation of transfected cells by flow cytometry before transcriptome analysis. Experiments were carried out under estrogen depleted conditions, and cells isolated 48 hours after transfection.
|
| |
|
| Overall design |
Treatment vs. Control
|
| |
|
| Contributor(s) |
Seksenyan A, Kaye J, Kadavallore A, Walts AE, de la Torre B, Berel D, Strom SP, Aliahmad P, Funari V |
| Citation(s) |
25632947 |
| |
| Submission date |
May 21, 2014 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Wolf Wiedemeyer |
| Organization name |
Cedars-Sinai
|
| Department |
BMS
|
| Street address |
8700 Beverly Blvd.
|
| City |
Los Angeles |
| State/province |
California |
| ZIP/Postal code |
90048 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (4)
|
| GSM1395172 |
Empty Vector Control for transient transfection replicate 1 |
| GSM1395173 |
Empty Vector Control for transient transfection replicate 2 |
| GSM1395174 |
Experiment TOX3 transient transfection replicate 1 |
| GSM1395175 |
Experiment TOX3 transient transfection replicate 2 |
|
| Relations |
| BioProject |
PRJNA248263 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE57856_RAW.tar |
17.7 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...