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| Status |
Public on Aug 12, 2014 |
| Title |
Gene Expression Profiles in Chronic Idiopathic Urticaria |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Lesions of chronic idiopathic urticaria (CIU) showed significant up-regulation of 506 genes and reduced expression of 51 genes.
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| Overall design |
We enrolled 8 patients with CIU and 6 healthy controls and obtained 4mm punch biopsies of active lesions and unaffected skin of patients with CIU and of skin from normal controls. Routine histologic evaluation was performed, RNA was isolated and gene expression data was determined using an Affymetrix Human Gene 1.0 ST Array (www.affymetrix.com). Due to technical reasons, the final evaluation included 6 samples of lesional skin, 7 samples of non-lesional skin and 5 samples of normal skin.
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| Contributor(s) |
Dreskin SC |
| Citation(s) |
26302730 |
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| Submission date |
Apr 29, 2014 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Stephen C Dreskin |
| E-mail(s) |
stephen.dreskin@ucdenver.edu
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| Phone |
303 724-7190
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| Organization name |
University of Colorado Denver
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| Department |
Division of Allergy and Clinical Immunology, Department of Medicine
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| Lab |
Dreskin Lab
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| Street address |
12700 E 19th Ave
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| City |
Aurora |
| State/province |
CO |
| ZIP/Postal code |
80045 |
| Country |
USA |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (18)
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| GSM1376740 |
Patient 2, control tissue |
| GSM1376741 |
Patient 3, lesion tissue |
| GSM1376742 |
Patient 3, control tissue |
| GSM1376743 |
Patient 4, lesion tissue |
| GSM1376744 |
Patient 4, control tissue |
| GSM1376745 |
Patient 6, lesion tissue |
| GSM1376746 |
Patient 6, control tissue |
| GSM1376747 |
Patient 7, lesion tissue |
| GSM1376748 |
Patient 7, control tissue |
| GSM1376749 |
Patient 8, control tissue |
| GSM1376750 |
Normal 11, control tissue |
| GSM1376751 |
Normal 12, control tissue |
| GSM1376752 |
Normal 13, control tissue |
| GSM1376753 |
Normal 14, control tissue |
| GSM1376754 |
Normal 15, control tissue |
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| Relations |
| BioProject |
PRJNA245834 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE57178_RAW.tar |
74.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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