|
| Status |
Public on Feb 20, 2015 |
| Title |
Activin A and BMP4 Modulation of Wnt/β-catenin Signaling Directs Fate Specification of Mesoderm Derivatives from Human Embryonic Stem Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the derivation of 2 different methods of generating cardiac myocytes from human ESCs. The traditional route is via cardiac progenitor cells and the second, new approach is through re-directing hemogenic endothelium into the cardiac lineage using inhibition of Wnt/b-catenin signaling
|
| |
|
| Overall design |
Examination of 2 different cardiac populations using RNA-seq
|
| |
|
| Contributor(s) |
Palpant NJ, Murry CE |
| Citation missing |
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| |
| Submission date |
Feb 22, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Chuck Murry |
| E-mail(s) |
murry@u.washington.edu
|
| Phone |
(206) 616-8684
|
| Organization name |
University of Washington
|
| Department |
Institute for Stem Cell and Regenerative Medicine, Center for Cardiovascular Biology
|
| Street address |
850 Republican St., Box 358050
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA239168 |
| SRA |
SRP038767 |
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