GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE54576 Query DataSets for GSE54576
Status Public on May 20, 2015
Title An analysis of genomic structural alteration in three human ES cell lines.
Organism Homo sapiens
Experiment type SNP genotyping by SNP array
Summary To elucidate frequencies of genomic structural alterations, we performed an analysis using a SNP genotyping array (Illumina HumanCytoSNP-12 v2.1 DNA Analysis BeadChip Kit) for three human ES cell lines, namely, SEES-1, SEES-2, and SEES-3. Samples were collected after 4 to 60 passages to detect structural mutations occurred during the cell cultivation processes. Our results suggested a higher genomic stability of the ES cells compared to some well-known normal cell lines.
Overall design Several samples were collected after 4 to 60 passages and subjected to the SNP genotyping array. We searched for structural mutations occurred during the culture of the ES cells.
Contributor(s) Akutsu H, Nakabayashi K, Okamura K, Hata K, Umezawa A
Citation(s) 24970375
Submission date Jan 30, 2014
Last update date Dec 18, 2017
Contact name Akihiro Umezawa
Phone 81-3-5494-7047
Organization name National Center for Child Health and Development
Department Center for Regenerative Medicine
Street address 2-10-1 Okura
City Setagaya-ku
State/province Tokyo
ZIP/Postal code 157-8535
Country Japan
Platforms (1)
GPL13829 Illumina HumanCytoSNP-12 v2.1 BeadChip
Samples (11)
GSM1319241 SEES1 at passage 4
GSM1319242 SEES1 at passage 10
GSM1319243 SEES1 at passage 25
BioProject PRJNA237441

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE54576_raw_signal_intensities.txt.gz 43.3 Mb (ftp)(http) TXT
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap