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| Status |
Public on Jan 09, 2014 |
| Title |
The Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites (Affymetrix microarray analysis) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We have mapped transcriptional changes after depletion of the histone demethylases JMJD2C/GASC1/KDM4C and JMJD2A/KDM4A alone or in combination in the esophageal squamous carcinoma cell line, KYSE150. The KYSE150 cell line contains an amplification of the JMJD2C locus.
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| |
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| Overall design |
RNA was extracted from KYSE150 cells transfected with shRNAs targeting JMJD2C and/or JMJD2A. The experiment was performed in triplicates and expression levels analyzed using Affymetrix microarrays.
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| |
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| Contributor(s) |
Pedersen MT |
| Citation(s) |
24396064 |
| |
| Submission date |
Jan 08, 2014 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Marianne Terndrup Pedersen |
| E-mail(s) |
marianne.pedersen@bric.ku.dk
|
| Organization name |
BRIC
|
| Department |
University of Copenhagen
|
| Lab |
Kim B. Jensen
|
| Street address |
Ole Maaloes Vej 5
|
| City |
Copenhagen N |
| ZIP/Postal code |
2200 |
| Country |
Denmark |
| |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE28332 |
The Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites |
|
| Relations |
| BioProject |
PRJNA234003 |
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