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| Status |
Public on Aug 22, 2013 |
| Title |
Gene expression in human breast cancer cell lines regulated by HIC1 gene |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
This study aimed to further our understanding of the role that hypermethylatioted in cancer 1 (HIC1) plays in breast cancer progression. Microarrays were searched for some genes that had correlated expression with HIC1 mRNA. According to fold-change screening between restoring expression of HIC1 and its respective control cells in MDA-MB-231 cells, or HIC1 knockdown and its respective control cells in HBL100, both up-regulated and down-regulated genes were shown.
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| Overall design |
The restoring expression HIC1 in MDA-MB-231 cells were respectively noted as MDAMB-231-HIC1 and the respective controls were noted as MDA-MB-231-GFP cells. HIC1 knockdown in HBL100 cells were noted as HBL100-shHIC1 and the respective control HBL100-shCtrl cell.
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| Contributor(s) |
Cheng G, Sun X, Wang J, Wang J |
| Citation(s) |
24295734 |
| |
| Submission date |
Aug 21, 2013 |
| Last update date |
Apr 23, 2018 |
| Contact name |
Gang Xiao |
| E-mail(s) |
xiaogangyhm@163.com
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| Organization name |
Shanghai Jiao-Tong University School of Medicine
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| Street address |
227 South Chongqing Road
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| City |
Shanghai |
| ZIP/Postal code |
200025 |
| Country |
China |
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| Platforms (2) |
| GPL14550 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA215902 |
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