|Public on Aug 22, 2013
|Gene expression in human breast cancer cell lines regulated by HIC1 gene
|Expression profiling by array
|This study aimed to further our understanding of the role that hypermethylatioted in cancer 1 (HIC1) plays in breast cancer progression. Microarrays were searched for some genes that had correlated expression with HIC1 mRNA. According to fold-change screening between restoring expression of HIC1 and its respective control cells in MDA-MB-231 cells, or HIC1 knockdown and its respective control cells in HBL100, both up-regulated and down-regulated genes were shown.
|The restoring expression HIC1 in MDA-MB-231 cells were respectively noted as MDAMB-231-HIC1 and the respective controls were noted as MDA-MB-231-GFP cells. HIC1 knockdown in HBL100 cells were noted as HBL100-shHIC1 and the respective control HBL100-shCtrl cell.
|Cheng G, Sun X, Wang J, Wang J
|Aug 21, 2013
|Last update date
|Apr 23, 2018
|Shanghai Jiao-Tong University School of Medicine
|227 South Chongqing Road
|Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version)
|Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)