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Series GSE50061 Query DataSets for GSE50061
Status Public on Aug 22, 2013
Title Gene expression in human breast cancer cell lines regulated by HIC1 gene
Organism Homo sapiens
Experiment type Expression profiling by array
Summary This study aimed to further our understanding of the role that hypermethylatioted in cancer 1 (HIC1) plays in breast cancer progression. Microarrays were searched for some genes that had correlated expression with HIC1 mRNA. According to fold-change screening between restoring expression of HIC1 and its respective control cells in MDA-MB-231 cells, or HIC1 knockdown and its respective control cells in HBL100, both up-regulated and down-regulated genes were shown.
Overall design The restoring expression HIC1 in MDA-MB-231 cells were respectively noted as MDAMB-231-HIC1 and the respective controls were noted as MDA-MB-231-GFP cells. HIC1 knockdown in HBL100 cells were noted as HBL100-shHIC1 and the respective control HBL100-shCtrl cell.
Contributor(s) Cheng G, Sun X, Wang J, Wang J
Citation(s) 24295734
Submission date Aug 21, 2013
Last update date Apr 23, 2018
Contact name Gang Xiao
Organization name Shanghai Jiao-Tong University School of Medicine
Street address 227 South Chongqing Road
City Shanghai
ZIP/Postal code 200025
Country China
Platforms (2)
GPL14550 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (4)
GSM1213411 MDA-MB-231_GFP_sample
GSM1213412 MDA-MB-231_HIC1_sample
GSM1213413 HBL100_shCtrl_sample
BioProject PRJNA215902

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50061_RAW.tar 39.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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