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| Status |
Public on Apr 04, 2013 |
| Title |
Determination of the serum miRNA expression profile in human moyamoya disease (MMD) |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Moyamoya disease (MMD) is a cerebrovascular disease characterized by progressive stenosis of the intracranial internal carotid arteries and their proximal branches. However, the etiology of this rare disease remains widely unknown. Serum microRNA (miRNA) profiles have been screened to identify novel biomarkers for disease diagnosis and prognosis. Here, we identified important serum miRNAs that might play important roles in contributing to MMD pathogenesis through microarray analysis.
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| Overall design |
10 MMD patients and 10 controls were consecutively recruited at Shanghai Changhai Hospital. Five-ml venous blood was collected from each participant and separated into serum and cellular fractions. We pooled serum samples from 10 MMD patients and 10 controls. Agilent Human 8 x 60K miRNA Array was performed on the two pooled samples.
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| Contributor(s) |
Dai D |
| Citation missing |
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| Submission date |
Apr 03, 2013 |
| Last update date |
Apr 06, 2013 |
| Contact name |
Dongwei Dai |
| E-mail(s) |
lsykxy@126.com
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| Organization name |
Changhai Hospital
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| Street address |
168 Changhai Road
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| City |
Shanghai |
| ZIP/Postal code |
200433 |
| Country |
China |
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| Platforms (1) |
| GPL15159 |
Agilent-031181 Unrestricted_Human_miRNA_V16.0_Microarray 030840 (Probe Name version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA196151 |
