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Series GSE45737 Query DataSets for GSE45737
Status Public on Apr 04, 2013
Title Determination of the serum miRNA expression profile in human moyamoya disease (MMD)
Organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Moyamoya disease (MMD) is a cerebrovascular disease characterized by progressive stenosis of the intracranial internal carotid arteries and their proximal branches. However, the etiology of this rare disease remains widely unknown. Serum microRNA (miRNA) profiles have been screened to identify novel biomarkers for disease diagnosis and prognosis. Here, we identified important serum miRNAs that might play important roles in contributing to MMD pathogenesis through microarray analysis.
Overall design 10 MMD patients and 10 controls were consecutively recruited at Shanghai Changhai Hospital. Five-ml venous blood was collected from each participant and separated into serum and cellular fractions. We pooled serum samples from 10 MMD patients and 10 controls. Agilent Human 8 x 60K miRNA Array was performed on the two pooled samples.
Contributor(s) Dai D
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Submission date Apr 03, 2013
Last update date Apr 06, 2013
Contact name Dongwei Dai
Organization name Changhai Hospital
Street address 168 Changhai Road
City Shanghai
ZIP/Postal code 200433
Country China
Platforms (1)
GPL15159 Agilent-031181 Unrestricted_Human_miRNA_V16.0_Microarray 030840 (Probe Name version)
Samples (2)
GSM1113425 Serum_MMD_pooled, rep1
GSM1113426 Serum_control_pooled, rep1
BioProject PRJNA196151

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45737_RAW.tar 10.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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