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| Status |
Public on Dec 24, 2013 |
| Title |
Gene expression profiles in isolated proximal tubules and whole kidneys of rats after cisplatin-administration |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
To clarify the effects of cisplatin (cis-diamminedichloroplatinum II, CDDP) on the gene expression profiles in renal proximal tubules, microarray analyses were carried out using total RNA samples isolated from microdissected proximal tubules and whole kidneys. The molecular events underlying acute kidney injury (AKI) in the proximal tubules of rats with cisplatin-induced nephrotoxicity were successfully clarified with 17,000 transcripts.
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| Overall design |
Renal proximal tubules were isolated under microscopy, and transcriptome data were collected with Rat Genome Survey Microarray® (Applied Biosystems)
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| Contributor(s) |
Masuda S, Nishihara K |
| Citation missing |
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| Submission date |
Apr 10, 2012 |
| Last update date |
Dec 25, 2013 |
| Contact name |
Satohiro Masuda |
| E-mail(s) |
masuda@kuhp.kyoto-u.ac.jp
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| Phone |
+81-75-751-3586
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| Fax |
+81-75-751-3586
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| Organization name |
Kyoto University Hospital
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| Department |
Pharmacy
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| Lab |
Masuda
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| Street address |
Shogoin
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| City |
Kyoto |
| ZIP/Postal code |
606-8507 |
| Country |
Japan |
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| Platforms (1) |
| GPL2996 |
ABI Rat Genome Survey Microarray |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA158411 |
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