|
| Status |
Public on Nov 02, 2012 |
| Title |
Promoter context-specific positive and negative transcriptional regulation of Glucocorticoid Receptor target genes by coregulator G9a |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
A549 lung cancer cells were not infected (NI), transfected by plasmids containing shG9a (sequence targeting G9a gene) or shNS (non-specific sequence).
These cells were treated with dex to identify subsets of genes regulated by dex (hormone) and G9a (EHMT2)
|
| |
|
| Overall design |
Cells (NI/shNS/shG9a) were treated with 100nM dex for 24h and total RNA was extracted to identify differentially expressed genes
|
| |
|
| Contributor(s) |
Stallcup MR, Siegmund KD, Bittencourt D, Wu D, Jeong KW, Ianculescu I, Gerke DS |
| Citation(s) |
23151507 |
| Submission date |
Feb 21, 2012 |
| Last update date |
Mar 20, 2017 |
| Contact name |
Dai-Ying Wu |
| Organization name |
University of Southern California
|
| Department |
Biochemistry
|
| Lab |
Stallcup
|
| Street address |
1441 Eastlake Ave, NOR 6314
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90033 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6883 |
Illumina HumanRef-8 v3.0 expression beadchip |
|
| Samples (19)
|
|
| Relations |
| BioProject |
PRJNA152057 |
Less...
More...