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Series GSE35476 Query DataSets for GSE35476
Status Public on Aug 31, 2012
Title Array CGH analysis of human colorectal tumors
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary The concept of the CpG island methylator phenotype (CIMP) in colorectal cancers (CRCs) is widely accepted, though the timing of its occurrence and its interaction with other genetic defects early during carcinogenesis remains largely unknown. Our aim was to uncover the molecular evolution of CIMP CRCs through integrative analysis of endoscopic, histological and molecular signatures in precancerous and malignant colorectal lesions.
Overall design A total of 84 endoscopically obtained human colorectal tumor was analyzed using Agilent CGH microarray. Copy number aberration was compared with clinicopathological features and DNA methylation status.
Contributor(s) Yamamoto E, Suzuki H
Citation(s) 22995252
Submission date Feb 01, 2012
Last update date Dec 06, 2012
Contact name Eiichiro Yamamoto
Phone +81-11-611-2111
Organization name Sapporo medical university
Street address South-1, West-16, Chuo-ku
City Sapporo
ZIP/Postal code 060-8543
Country Japan
Platforms (1)
GPL10123 Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version)
Samples (84)
GSM869119 Human Colon Tumor Tissue 1
GSM869120 Human Colon Tumor Tissue 2
GSM869121 Human Colon Tumor Tissue 3
This SubSeries is part of SuperSeries:
GSE35534 Genome-wide copy number aberrations and methylation profiles in human colorectal lesions
BioProject PRJNA156117

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE35476_RAW.tar 2.3 Gb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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