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Series GSE30023 Query DataSets for GSE30023
Status Public on Jul 15, 2013
Title A comparative gene expression profiling of spondyloarthropathy and rheumatoid arthritis using oligonucleotide based microarrays
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Comparative gene expression profiling of mononuclear cells from synovial fluid samples of rheumatoid arthritis (RA) and
spondyloarthropathy (SpA) cases was performed. A total of 72 transcripts were found to be differentially expressed in RA compared
to SpA, with p-value threshold of 0.05 and using the Benjamini-Hochberg False Discovery rate multiple comparison corrections.
From the list, 57 transcripts were found to be upregulated in RA as compared to SpA and 15 downregulated by a fold
change cut-off of 1.5-fold.
Overall design The proposed study carried out mRNA expression profiling of mononuclear cells from synovial fluid samples of seven RA and five SpA cases. We have used 4X44K and 1X44K arrays from Agilent Technologies platform. Based on the RNA integrity, selected molecules were processed further using single-color microarray based gene expression. The raw data files obtained from this study were eventually analyzed with R package of the BioConductor suite.
Contributor(s) Pandey A
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Submission date Jun 16, 2011
Last update date Feb 22, 2018
Contact name Akhilesh Pandey
Phone 91 080 28416140
Organization name Institute of Bioinformatics
Street address UnitI, Discoverer building, ITPL
City Bangalore
State/province Karnataka
ZIP/Postal code 560 066
Country India
Platforms (2)
GPL1708 Agilent-012391 Whole Human Genome Oligo Microarray G4112A (Feature Number version)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (12)
GSM743016 Synovial fluid of Rheumatoid arthritis (RA) sample 1
GSM743017 Synovial fluid of Rheumatoid arthritis (RA) sample 2
GSM743018 Synovial fluid of Rheumatoid arthritis (RA) sample 3
BioProject PRJNA143705

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE30023_RAW.tar 84.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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