|
| Status |
Public on Nov 29, 2011 |
| Title |
The role of a novel CAR-induced gene TUBA8 in hepatocellular carcinoma cell lines |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The Tuba8 gene was identified as a CAR-regulated gene that was induced during phenobarbital (PB) promotion of liver tumor. TUBA8 was then over-expressed in heaptocarcinoma cells to determine the function of TUBA8.
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| |
|
| Overall design |
First, identify genes that are regulated by CAR and are induced during liver tumor development. Second, overexpressiong of an identified gene in transformed cells to detemine the biolgical function of the gene product. In this manuscript, the TUBA8 gene was examined.
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| |
|
| Contributor(s) |
Kamino H, Moore R, Negishi M |
| Citation(s) |
21872825 |
| |
| Submission date |
May 06, 2011 |
| Last update date |
Dec 06, 2012 |
| Contact name |
NIEHS Microarray Core |
| E-mail(s) |
microarray@niehs.nih.gov, liuliw@niehs.nih.gov
|
| Organization name |
NIEHS
|
| Department |
DIR
|
| Lab |
Microarray Core
|
| Street address |
111 T.W. Alexander Drive
|
| City |
RTP |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL891 |
Agilent-011978 Mouse Microarray G4121A (Feature Number version) |
|
| Samples (6)
|
| GSM720953 |
DEN-PB WT-39W vs. DEN-PB CAR-KO-39W |
| GSM720954 |
DEN-PB CAR-KO-39W vs. DEN-PB WT-39W |
| GSM720955 |
DEN-CAR-KO 39W vs. DEN-PB CAR-KO-39W |
| GSM720956 |
DEN-PB CAR-KO-39W vs. DEN-CAR-KO 39W |
| GSM720957 |
DEN-PB CAR-KO-39W vs. DEN-PB tumor-39W |
| GSM720958 |
DEN-PB tumor-39W vs. DEN-PB CAR-KO-39W |
|
| Relations |
| BioProject |
PRJNA140371 |
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