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Series GSE25229 Query DataSets for GSE25229
Status Public on Nov 01, 2012
Title Genome-wide analysis of unbalanced chromosomal changes in colorectal carcinoma
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Genome variation profiling by genome tiling array
Summary Colorectal carcinoma (CRC) is often characterized by chromosomal instability (CIN) which has been associated with a poor prognosis. Disease-related de novo methylation often causes gene repression that may complement chromosomal losses or mutations. To compare CpG island methylation and chromosomal abnormalities in colorectal cancer, we determineded unbalanced chromosomal changes by aCGH of CRCs that were also profiled for aberrant de novo DNA methylation at 23,000 CpG islands of the human genome (Gebhard et al. 2010; and unpublished data).

This SuperSeries is composed of the SubSeries listed below.
Overall design Refer to individual Series.
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Submission date Nov 09, 2010
Last update date Jan 17, 2013
Contact name Michael Rehli
Organization name University Hospital Regensburg
Department Internal Med III
Street address F.-J.-Strauss-Allee 11
City Regensburg
ZIP/Postal code 93042
Country Germany
Platforms (2)
GPL8544 Human CpG Island Microarray 244K (Agilent-014791) with extended custom annotation
GPL10123 Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version)
Samples (36)
GSM436520 Colorectal carcinoma CRC01 [MCIp]
GSM436521 Colorectal carcinoma CRC02 [MCIp]
GSM436522 Colorectal carcinoma CRC03 [MCIp]
This SuperSeries is composed of the following SubSeries:
GSE25221 CpG island methylation in colorectal cancer
GSE25228 Chromosomal abnormalities in colorectal cancer
BioProject PRJNA134471

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE25229_RAW.tar 2.1 Gb (http)(custom) TAR (of TXT)

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