|
| Status |
Public on Mar 21, 2023 |
| Title |
Human alveolar hydrogels promote morphological and transcriptional differentiation in iPSC-derived alveolar type 2 epithelial cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the role of alveolar extracellular matrix (aECM) hydrogels on iPSC-derived alveolar type 2 epithelial cell (iAT2) morphological and transcriptional differentiation
|
| |
|
| Overall design |
We analyzed RNA collected from iAT2s grown in two different densities of aECM hydrogels (8mg/mL and 30mg/mL) compared to Matrigel at Day 4 and Day 8
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| |
|
| Contributor(s) |
Hoffman ET, Uriarte JJ, Uhl FE, Eckstrom K, Tanneberger AE, Becker C, Moulin C, Asarian L, Ikonomou L, Kotton DN, Weiss DJ |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 16, 2023 |
| Last update date |
Mar 21, 2023 |
| Contact name |
Korin Eckstrom |
| E-mail(s) |
korin.eckstrom@med.uvm.edu
|
| Organization name |
University of Vermont
|
| Street address |
89 Beaumont Ave
|
| City |
Burlington |
| State/province |
VT |
| ZIP/Postal code |
05405 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
|
| Samples (18)
|
| GSM7102499 |
iPSC-derived AT2 cells; Matrigel; Day 4 M4A |
| GSM7102500 |
iPSC-derived AT2 cells; Matrigel; Day 4 M4B |
| GSM7102501 |
iPSC-derived AT2 cells; Matrigel; Day 4 M4C |
| GSM7102502 |
iPSC-derived AT2 cells; Matrigel; Day 8 M8A |
| GSM7102503 |
iPSC-derived AT2 cells; Matrigel; Day 8 M8B |
| GSM7102504 |
iPSC-derived AT2 cells; Matrigel; Day 8 M8C |
| GSM7102505 |
iPSC-derived AT2 cells; 8mg/mL aECM hydrogels; Day 4 84A |
| GSM7102506 |
iPSC-derived AT2 cells; 8mg/mL aECM hydrogels; Day 4 84B |
| GSM7102507 |
iPSC-derived AT2 cells; 8mg/mL aECM hydrogels; Day 4 84C |
| GSM7102508 |
iPSC-derived AT2 cells; 8mg/mL aECM hydrogels; Day 8 88A |
| GSM7102509 |
iPSC-derived AT2 cells; 8mg/mL aECM hydrogels; Day 8 88B |
| GSM7102510 |
iPSC-derived AT2 cells; 8mg/mL aECM hydrogels; Day 8 88C |
| GSM7102511 |
iPSC-derived AT2 cells; 30mg/mL aECM hydrogels; Day 4 34A |
| GSM7102512 |
iPSC-derived AT2 cells; 30mg/mL aECM hydrogels; Day 4 34B |
| GSM7102513 |
iPSC-derived AT2 cells; 30mg/mL aECM hydrogels; Day 4 34C |
| GSM7102514 |
iPSC-derived AT2 cells; 30mg/mL aECM hydrogels; Day 8 38A |
| GSM7102515 |
iPSC-derived AT2 cells; 30mg/mL aECM hydrogels; Day 8 38B |
| GSM7102516 |
iPSC-derived AT2 cells; 30mg/mL aECM hydrogels; Day 8 38C |
|
| Relations |
| BioProject |
PRJNA945479 |
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