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| Status |
Public on Jan 11, 2023 |
| Title |
RNA-seq analysis of young adult daf-18(ok480) and control worms |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNA-seq analysis was used to identify the gene expression changes in male and hermaphroditie when daf-18 is lost. Based on these sequencing data, the genes that were up-regulated or down-regulated by at least 2 times (|log2 (folding change) | ≥ 1 and padj ≤ 0.05) were analyzed. The analysis of these differentially expressed genes' pathway and gene ontology (GO) enrichment shows that the influence of different genders after daf-18 deletion is enriched to some signal pathways, including longevity and protein degradation pathway in endoplasmic reticulum, etc.
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| Overall design |
The mRNA profile changes of each sex when daf-18 is lost, were generated by deep sequencing. Use Illumina Gallx
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| Contributor(s) |
Zheng S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 09, 2023 |
| Last update date |
Jan 11, 2023 |
| Contact name |
Shanqing Zheng |
| E-mail(s) |
zhengshanqing@henu.edu.cn
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| Phone |
+8637122892869
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| Organization name |
Henan university
|
| Street address |
1 Jinming Avenue North, Longting District, School of Basic Medical Sciences, Henan University
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| City |
Kaifeng |
| ZIP/Postal code |
475004 |
| Country |
China |
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| Platforms (1) |
| GPL13657 |
Illumina HiSeq 2000 (Caenorhabditis elegans) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA922122 |
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