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| Status |
Public on Jun 12, 2010 |
| Title |
Caenorhabditis elegans infected with Staphylococcus aureus |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
|
| Summary |
Young adult fer-15;fem-1 Caenorhabditis elegans were infected with Staphylococcus aureus for 8 h to determine the transcriptional host response to Staphylococcus aureus. Analysis of differential gene expression in C. elegans young adults exposed to two different bacteria: E. coli strain OP50 (control), wild-type Staphylococcus aureus RN6390. Samples were analyzed at 8 hours after exposure to the different bacteria. These studies identified C. elegans genes induced by pathogen infection.
Keywords: response to pathogen infection, innate immunity, host-pathogen interactions
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| Overall design |
There are 6 samples total: 3 biological replicates of Staphylococcus aureus-infected animals, and 3 biological replicates of E. coli-fed controls. Three independent biological replicates were isolated for each treatment. All treatments were performed in parallel.
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| Contributor(s) |
Troemel ER, Irazoqui JE, Ausubel FM |
| Citation(s) |
20617181, 24882217 |
| |
| Submission date |
May 13, 2010 |
| Last update date |
Jul 06, 2016 |
| Contact name |
Javier E Irazoqui |
| E-mail(s) |
jirazoqui@partners.org
|
| Phone |
16176437063
|
| Fax |
16177243248
|
| Organization name |
Massachusetts General Hospital
|
| Department |
Pediatrics
|
| Lab |
Ausubel
|
| Street address |
55 Fruit St GRJ1416
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02114 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA127265 |
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