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| Status |
Public on Feb 28, 2023 |
| Title |
Augmenting vaccine efficacy against delta variant with ‘Mycobacterium-w’ mediated modulation of NK-ADCC and TLR-MYD88 pathways |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Fifty healthcare workers (HCW) who had received Mycobacterium-w (Mw) and at least one dose of ChAdOx1 nCoV-19 vaccine subsequently (Mw+ChAdOx1 group) were monitored for symptomatic COVID-19, during a major outbreak with the delta variant of SARS-CoV-2 (April-June, 2021) in India, along with 201 HCW receiving both doses of the vaccine without Mw (ChAdOx1 group). Bulk RNA-Seq analysis was carried out on 4 subjects enrolled from each group.
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| Overall design |
Comparative gene expression analysis between 4 subjects from Mw + ChAdOx1 and ChAdOx1 group.
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| Contributor(s) |
Jaiswal SR, Saifullah A, Arunachalam J, Lakhchaura R, Tailor D, Mehta A, Bhagawati G, Aiyer H, Biswas S, Khamar B, Malhotra SV, Chakrabarti S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 28, 2022 |
| Last update date |
Feb 28, 2023 |
| Contact name |
Suparno Chakrabarti |
| Organization name |
Manashi Chakrabarti Foundation
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| Department |
Cellular Therapy and Immunology
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| Street address |
PGH Shah Road
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| City |
Kolkata |
| State/province |
West Bengal |
| ZIP/Postal code |
700032 |
| Country |
India |
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| Platforms (1) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA895436 |
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