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Series GSE216811 Query DataSets for GSE216811
Status Public on Feb 28, 2023
Title Augmenting vaccine efficacy against delta variant with ‘Mycobacterium-w’ mediated modulation of NK-ADCC and TLR-MYD88 pathways
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Fifty healthcare workers (HCW) who had received Mycobacterium-w (Mw) and at least one dose of ChAdOx1 nCoV-19 vaccine subsequently (Mw+ChAdOx1 group) were monitored for symptomatic COVID-19, during a major outbreak with the delta variant of SARS-CoV-2 (April-June, 2021) in India, along with 201 HCW receiving both doses of the vaccine without Mw (ChAdOx1 group). Bulk RNA-Seq analysis was carried out on 4 subjects enrolled from each group.
 
Overall design Comparative gene expression analysis between 4 subjects from Mw + ChAdOx1 and ChAdOx1 group.
 
Contributor(s) Jaiswal SR, Saifullah A, Arunachalam J, Lakhchaura R, Tailor D, Mehta A, Bhagawati G, Aiyer H, Biswas S, Khamar B, Malhotra SV, Chakrabarti S
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Submission date Oct 28, 2022
Last update date Feb 28, 2023
Contact name Suparno Chakrabarti
Organization name Manashi Chakrabarti Foundation
Department Cellular Therapy and Immunology
Street address PGH Shah Road
City Kolkata
State/province West Bengal
ZIP/Postal code 700032
Country India
 
Platforms (1)
GPL24106 MinION (Homo sapiens)
Samples (8)
GSM6693243 Cs1
GSM6693244 Cs2
GSM6693245 Cs3
Relations
BioProject PRJNA895436

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE216811_Mw_Cs_DEGs.xlsx 525.4 Kb (ftp)(http) XLSX
GSE216811_Mw_Cs_Raw_reads.xlsx 704.2 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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