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| Status |
Public on Jul 17, 2024 |
| Title |
Epigallocatechin Gallate modulates microglia phenotype |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We have identified Epigallocatechin Gallate (EGCG) as a potent modulator of microglia function. Our aim was to determine whether EGCG affects the transcriptome of microglia and identify genes and gene sets that may underly the effects of EGCG on microglia function.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for primary murine (CD1) microglia treated with 1uM EGCG or equivalent DMSO control for 24 hours in serum free media. 2 indendent biological replicates were included for both treatment conditions.
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| Contributor(s) |
Regan P, Sero J, Williams RJ |
| Citation(s) |
38095777 |
| |
| Submission date |
Jul 13, 2022 |
| Last update date |
Jul 17, 2024 |
| Contact name |
Robert J Williams |
| E-mail(s) |
rjw38@bath.ac.uk
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| Organization name |
University of Bath
|
| Street address |
University Of Bath, The Avenue, Claverton Down
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| City |
Bath |
| ZIP/Postal code |
BA2 7AY |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA858466 |
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